On this episode, Dr. Lupoi chats with the esteemed board-certified neurologist, psychopharmacology researcher, and author Dr. Ethan Russo. Discussion points include the endocannabinoid system (ECS) and our bodies seeming almost mechanized to utilize cannabinoids, whether a medical doctor can properly treat us without knowledge on the ECS, Dr. Russo's travels to South America in search of ethnobotanical plants, and a candid discourse on synthetic cannabinoids like delta-8-THC, THCP, and HHC.