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Episode 12 - Far UVC with Professor Kirk Atkinson PhD
Episode 1229th April 2022 • COVID19 The Answers • Dr Funmi Okunola
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Professor Kirk Atkinson talks about Far UVC and its ability to kill the SARS-CoV-2 virus and other pathogens.

Learn more: https://kojalamedical.com/covid19theanswers/

Scientific Research Links:

“Far-UVC light (222 nm) efficiently and safely inactivates airborne human coronaviruses” - https://www.nature.com/articles/s41598-020-67211-2?mc_cid=98d0b3d652&mc_eid=c7429e3ec7#change-history

“Predicting airborne coronavirus inactivation by far-UVC in populated rooms using a high-fidelity coupled radiation-CFD model” - https://www.nature.com/articles/s41598-020-76597-y

“Improved estimates of 222 nm far-UVC susceptibility for aerosolized human coronavirus via a validated high-fidelity coupled radiation-CFD code” - https://www.nature.com/articles/s41598-021-99204-0

Professor David J Brenner, Columbia University - http://www.columbia.edu/~djb3/Far%20UVC.html

“Inactivation Rates for Airborne Human Coronavirus by Low Doses of 222 nm Far-UVC Radiation” - https://www.mdpi.com/1999-4915/14/4/684

“Extreme Exposure to Filtered Far-UVC: A Case Study” - https://onlinelibrary.wiley.com/doi/full/10.1111/php.13385

Transcripts

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Kojala Medical presents COVID-19, The  Answers. The show that delivers the

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scientific evidence-based knowledge that can  safely return us all to our pre-COVID lives.

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My name is Dr. Funmi Okunola  and I'll be hosting the show.

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Every week you can listen to me  interview a highly respected professional

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about the science that can reduce your risk  of becoming infected with this Coronavirus.

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Hello and welcome to COVID-19 The  Answers Episode 12 – Far UVC. I’d

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like to welcome Professor Kirk Atkinson PhD.

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Professor Atkinson is an Associate  Professor & Associate Industrial Research

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Chair of Energy Systems and Nuclear Science  at Ontario Tech University in Canada.

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Dr Atkinson graduated from the University of  London with a BSc in Theoretical Physics in 1999,

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an MSc in Astrophysics in 2001, and an  MRes in Image and X-ray Physics in 2002.

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He then joined the Ministry of Defence  as Senior Lecturer in Nuclear Science in

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the Nuclear Department, the UK’s only  dedicated Nuclear Engineering School.

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He became Technical Lead for Reactor  Physics and High Performance Computing

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and for Radiation Physics and Criticality.  Since 2014, in collaboration with Rolls-Royce,

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he led a multi-million dollar technical effort  to develop a high-throughput Gamma Emission

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Tomography system (EGRET) for imaging and  characterisation of spent nuclear fuel.

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He joined the Faculty of Energy Systems and  Nuclear Science at Ontario Tech University

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as an Associate Professor in January 2019 and  began collaborating with research into Far UVC

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with Professor David Brenner’s  team at Columbia University

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Welcome. Hi. So Kirk, could you tell the audience  what led you into the world of far UVC technology?

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I had a background for my PhD  work in in Radiation Biology

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and I found myself a little bit stuck moving my  family, from funnily enough, from the UK to Canada

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and I was trying to leverage  my my skills and experience

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with that background and my background in  nuclear engineering and modeling and simulation

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and I sort of stumbled across the work that  David Brenner had been doing, who I knew from

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before at Columbia University and I noticed that  whilst they were doing some really good stuff

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in the experimental side the widespread  application how it would work in practice

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in the in the environment in a building  wasn't really well worked out at all

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so they've concentrated much more on  the laboratory studies in the science of

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how it does the killing rather than how it would  work in practice and so with some colleagues from

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the UK we decided to do some some simulation work  to try and figure this this kind of thing out

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and it's been quite influential I think in terms  of the findings that we've that we've found

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and we've actually been able to help the Brenner  group interpret some of their their work and

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actually found that far UVC is even better than  we thought it was gonna be. Oh that's fantastic!

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So electromagnetic radiation is a term used to

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describe all the different kind of energies  released into space by stars such as the sun

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the energy travels at the speed of light  and is in the form of waves and photons

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when you wake up and see the light from the sun  tune your radio watch tv send a text message or

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warm warm food in a microwave oven you are using  electromagnetic energy you depend on this energy

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every hour of every day without it the world  you know could not exist in the electromagnetic

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spectrum there are all types of electromagnetic  radiation with various frequencies and wavelengths

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the most well known are radio waves microwaves  infrared visible light ultraviolet and x-rays

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the electromagnetic waves in each of these  bands have different characteristics such

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as how they are produced how they interact  with matter and their practical applications

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today we will be discussing ultraviolet light  or UV light and far UVC light in particular

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as it relates to the preventative measures  for Covid this technology is widely unknown

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and safety of use will be a major concern  to educate medical and non-medical people

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UV light has different properties and uses in  industry in everyday life as well as pandemic

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management and risk mitigation so Kirk before  we dive into this technology and its application

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for COVID risk mitigation. Let's begin with  a very basic understanding of the technology.

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Can you briefly describe the three different  types of UV light and their uses UV A B and C?

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Sure, so UV light exists at shorter wavelengths  than visible light. So most of us maybe in school,

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did a little bit of physics and somewhere  along the line the acronym Richard Of York

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Gave Battle In Vain or ROY G BIV came up and  so you're going all the way from the red,

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the R, to the V, the violet. The violet is around  about 400 nanometers when you go a little bit

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too short, too shorter wavelength from there,  so below 400 maybe to as low as 315 nanometers.

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That's in the ultraviolet range and that's the  ultraviolet A range. So that's what we call UVA

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and that's the wavelength of light that we're  familiar with. It's what causes people to tan

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when they go in the sun. It's what causes skin  to age. If you don't moisturize and take care

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of your skin properly. So what you're using a bug  zapper. Now if you go to shorter wavelengths go a

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little bit shorter we hit the UVB range, so that's  between about 315 nanometers and 280 nanometers

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and that maybe less useful in some regards.  It can be responsible for causing melanoma in

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terms of skin cancer. It's one of the ones that we  know about a lot, so one of the reasons we should

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wear sunblock when we're in the sun, or protect  ourselves but it causes fluorescence. Okay. So you

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can use it in fluorescent applications go a little  bit shorter wavelength still below 280 nanometers

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and you enter the UVC range now that UVC range  pretty much exists between about 200 and 280

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nanometers there are bands of UV light that  exist at shorter wavelengths than that,

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what we would call the VUV and the EUV range  and they have specific properties as well,

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but if we focus on that 218 nanometers down  to 200 nanometers range, where we have UVC

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the most common kind of wavelength that  we know about around about 254 nanometers

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and that's used in sterilization purposes when  we go towards the far, towards the very short

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wavelength end that's where we hit what we call  far UVC. It's at the far end of the UVC range,

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it's always existed and it's it's really within  the range 230 nanometers down to about 200

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with the common ones being between 222 and 207  nanometers and that's really been an underutilized

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wavelength range. Right, and just to clarify  for the non-scientific audience. So UVB when

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you talk about fluorescence, you mean in  lighting, so for example nightclub lighting

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and that blue lighting you see that we sometimes  see in shots that kills bugs that's what

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UVBis used, well no that's not what UVB is used  for, it tends to the fluorescence. I mean in the

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sense here is more to do with particular kinds of  scientific applications you can get fluorescence

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at all different kind of wavelengths whether  it's UVA through to x-ray through to whatever

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all all fluorescence really is the  light that becomes emitted through

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the excitation of electrons in an atom so  if you go back to school, now many of us

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would have probably done chemistry class  maybe physics class and they would have

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remembered that the atom is kind of like has  a blob in the middle that's the nucleus where

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we've got some protons and stuff going on and  then orbiting around that and they the word,

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the important word here is orbiting are electrons  and those electrons can live in different shells

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so when we cause an electron to be to be  promoted from a lower shell to a higher shell

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it doesn't necessarily like to live at that higher  shell state so what it does is it relaxes back

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down and gives off light in the process and that's  fluorescence right okay and then UVC when you

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said it's used in kind of sterilizing properties  that's practically speaking that's things like our

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operating theaters they use UVC you know at night  don't they to sterilize them when nobody's around

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so that's one of its uses too is that right, so  UVC more recently has has been used so traditional

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UVC more recently has been used in the in the  operating room emergency room kind of context

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out of hours but for the longest time it's been  used in other contexts too many of us in here

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in here in canada and in maybe in the US and  other places might take water from from a well

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or has fairly unclean water from in the mains and  so they want to sterilize it now you can go down

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many hardware stores certainly here in Canada and  you can buy UV apparatus that will illuminate the

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water and kill the bugs that are in it you can  put the same kind of thing into HVAC systems,

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so the idea that it's been used for germicidal  purposes to kill germs has actually been around

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for about a hundred years and it's really, really  well established. Thank you and yes, Professor

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Jimenez talked about it a couple of weeks ago. Germicidal UV. What's

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the difference between conventional germicidal use  UVC lighting and far UVC lighting? Okay, so it's

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fundamentally down to wavelength, so germicidal  UV is pretty much what we would call 254 nanometer

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UVC, and that wavelength is what is one of the two  principal wavelengths that comes out of mercury

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gas discharge lamps which is the fundamental  traditional way of of making UV light

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has two particular wavelengths and one of them  gets absorbed in the in the glass so it doesn't

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make its way out but the 254 nanometer does so it  comes out of the bulb and there's there's a range

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of different types of bulb that you can have that  employ this technology some are very long some

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are small, you can you can find them in Canadian  Tire, I have one I bought one a while back myself

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the far UVC it is made at lower intensity in these  kind of lamps so it does exist there and if you

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could filter out all of the other wavelengths  that you don't want, you could use it, but it's

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not necessarily the most efficient way and what  the kind of revolution in this kind of field was

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was the use of plasma based light sources and  eczema lamps predominantly. And these eczema

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lamps, they use particular kind of diatomic  molecules that you can excite. Just like I

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talked about earlier with the electrons being  jumping up to a higher level and when they relax,

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they relax at particular wavelengths. One  of which is to around about 222 nanometers.

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Now that's not the only wavelength that comes out,  so you have to use a filter, a specific filter

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to filter out the components that you don't want,  but these new kind of lamps. They allowed greater

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intensities of this kind of two to two band made  the process of the filtering less troublesome so

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it's really only down to wavelength and the  big thing with far UVC is that it's safer

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than the conventional UVC. Do you want  to talk about that? Sure, sure. So

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if it kind of relates to the history of this  actually, so let's, if we went back some amount

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of years ten years, or so maybe a decade. It  was recognized and Brenner's group at Columbia

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University was was one of the pioneering  groups in this area it was recognized that

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far UVC wavelengths will

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penetrate less deeply into tissue which  is the fundamental bit that makes UVC

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light dangerous to us normally, so they came  along and they figured out if they took this lamp

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and they took this a particular kind of  filter and they brought it together they

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could make systems that could be used  to to cure pathogens to kill microbes

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now the way this kind of works is talking about  fluorescence I'm talking about electron movements,

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what happens is every time that radiation hits  material the atoms and molecules in that material

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their electrons get affected  by the energy that's coming in

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now they can get knocked out they can get promoted  to higher orbits where from where from they relax

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now UV a light actually penetrates really  deeply, this is kind of counterintuitive because

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as you go into shorter to shorter wavelengths  the frequency goes up and the energy goes up

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normally in life we think about things like  x-rays. X-rays are higher energy photons and we we

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largely think about them as being damaging and you  go to the hospital and you see the radiation sign

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on the door and you know you're not to go in there  because it can hurt you if it's not used properly.

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So this is where it's kind of counter-intuitive  in that UV-A has lower energy, but penetrates

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tissue more deeply. Thankfully it doesn't have  the energy to cause damage to DNA UVB does, which

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is why people get melanoma, UVC does, it goes  less far in but still hits cells that are living

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UV far UVC on the other hand is so energetic,  it interacts much more readily with atoms

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and molecules in the dead skin layers that we  have or the tear layer that we have on our eye

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and all the energy gets absorbed  before it hits anything that's living

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anything where we've got dna that could be hurt  and that's really the fundamental advantage

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about far UVC light is that whilst it's got  more energy and can cause damage it can't

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make it to those parts of us where we  could be harmed and I like to think about

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interactions a bit like if you went into a bar,  and you're trying to make your, it's a busy night

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and you come in the door and you're trying  to go to the bar, so you can buy a drink,

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or a coffee if you don't drink, if there's lots  of people in your way. You can have lots of

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interactions before you make it to the bar,

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if there's less people in the bar, you get  to the bar quicker and this is fundamentally

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what's happening with the difference between the  different types of light. So whilst it's carrying

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damaging energy, it has so many more interactions  on the way to the bar, the energy gets lost,

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so that's why it's so powerful right so we get  this unique property whereby it can kill germs

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unlike conventional UV light, it won't cause  cancers because it doesn't interact with DNA

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and living cells and it won't give us cataracts.  So we can have a light that shines directly on us,

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killing the coronavirus in the aerosols and you  know live happily without the dangers of cancer

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or cataracts. Absolutely and this is really  where a huge amount of work has now been done

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so prior to the pandemic there are a number of  groups obviously the Brenner group being one the

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Dundees and Andrews group in the UK group in  Japan. I think Kobe University and some others

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they were all already doing work on this? So  they were looking at they were exposing skin

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on in mice for instance and the eyes on mice  and they were seeing what the effects were

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and obviously since the pandemic this is has  taken off massively with many more groups

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joining the field and they all see the same  thing, you can put very large intensities of

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far UVC light on the skin and not get any damage  none at all and it's been repeated over and over

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and that's really reassuring that you know  that experimentation has been repeated and

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you there is a scientific consensus there so how  was far UVC discovered? So I kind of touched on

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that a moment ago when I sort of suggested that  around about a decade ago it was noted that

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these kind of wavelengths wouldn't be  able to penetrate as deeply through cells,

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through tissue and therefore not be able  to cause harm and so bringing together

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the technology that had evolved in the lamp space  eczema lamps and the like along with the right kind

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of filters allowed it to be exploited clearly  it's always existed because it's part of the

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electromagnetic spectrum it comes out of all UV  lamps and almost certainly is produced in the sun

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and it's produced all over it's just never been  able to be exploited because the technology wasn't

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really there to do it but once the technology was  there you can see the applications of it and that

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and that's where we find ourselves now okay so  in what scenarios and environments do you think

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far UVC would be most effective in the prevention  of Covid-19. Okay so I went to a conference last

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week. It was the first conference I've been to  in two years and a large number of people started

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the conference wearing masks, and they were trying  to be mindful of the fact that we know that Covid

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is carried in the air and they will be talking  to a lot of people but they realized that when

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they went into the reception hall and people had  had some canapes and a glass of wine and he had

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this big space with hundreds of people and pretty  poor airflow having a mask on was kind of moot,

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all the mask was doing was acting as a little  bit of a filter about what's going in and out

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the airflow in the room from the HVAC systems was  clearly insufficient to pull the air in and out.

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If we had had a technology like far UVC  illuminating all of that air while we were

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in there, the concentrations of SARS-CoV-2 or any  other airborne pathogen would be being reduced as

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the far UVC photons get absorbed in the bugs  in the air and cause them to be damaged and

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if they're damaged they then don't work properly,  and they can't infect you so the spaces where it's

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very useful is spaces where air flow is very,  very bad, so when you're outside in the world

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you have lots of air around you. The wind blows,  you know, other things there's lots of space, you

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dilute any of the kind of concentrations of virus  that people might breathe out so your risk level

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goes really far down, and that's good we like that  we know that if you go into a space and you have

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really good ventilation it works, you can pull  a lot of the a lot of the bugs out of the air,

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by exchanging the air you could run it through  a filter but the problem with all of those is

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they need to take the air somewhere else, and  whenever you can't do that or can't can't do that

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very well you're going to get it to build up so I  rode the via rail train from where I where I live

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to Ottawa for this conference and I was pretty  uninspired by the ventilation on the train,

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you can't open the windows, the windows are  sealed, it wasn't obvious that there was an

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aircon that was working properly there were  a ton of people in there eating a drinking

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so that's a terrible environment to have  circulation of aerosol in the air so having

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far UVC lights in in the in the ceiling  of the of the railroad car would be

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probably a good idea, similarly the classroom, I  have a lot of discussions with colleagues about

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whether we should have masking still in schools  or not and I try and make the point that a mask

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is just a filter however good the filter is  still only a filter, so if the filter is 50

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efficient, all that does is double the time before  you get the same concentration as you would have

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got anyway. If there's an infectious concentration  in the air, you sit in the room long enough

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it doesn't matter that you're wearing a mask,  now there are ways to get that out of the room

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but a lot of schools have put those kind of air  purifier devices at the front of the classroom,

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and so it pulls the air from the  back of the room to the front

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past the heads of all the kids it's kind of a  bit of a not well thought through problem here

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and it only is when it gets there does it do  with the cleaning so you're actually spreading

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the stuff around which you don't necessarily  want if you had them in the in the ceiling again

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you could kill some of the concentration of  the bugs in the air of all the bugs in the air

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doesn't really matter which and this has been  proven too whilst we sort of were the pioneers

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of of the modeling and simulation side  of this that my my colleagues and I

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the a group in the uk along with Columbia  University is very recently last month published

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published a good paper where they they have  actually done some room-sized chamber experiments

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and they found that far UVC can knock out  bacteria in the air down to two percent of the

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concentration a stable two percent on a constant  release in about five minutes that's that's

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equivalent to 184 air changes per hour for that  room and that's using standard UV limits as well

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fantastic performance yes that is that's amazing  because I mean the best HVAC system will give air

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changes of around six to nine I think from memory  and Professor Jimenez, so that's amazing, so

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and again I think it highlights that you  need some form of expertise or some form of

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regulated set up to help schools

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assess their environment and work out which  technologies to use I guess in tandem to provide

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the best risk reduction measure methods in terms  of removing the coronavirus, for sure I mean,

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I' m obviously pro far UVC, I think it's a very  good technique but like some other like so many

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other things in life it's not the only solution  and it's not like ‘oh you should only use far

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UVC rather than something else’ all measures are  needed, like everything in life. There is some

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context where it will work better that experiment  that I just spoke about was a very specific setup,

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but make that more complicated by having people  moving through the space you have obstructions

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so that the airflow is stalled, the room layout  is different everything then changes, so when

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people say that this technique or the other  technique will give this amount of performance

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yes it could under a certain specific set of  circumstances and this is where implementation

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is really the key thing it's understanding how  the interplay between aerosol HVAC or other

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ventilation other measures that we have in space  be it illumination be it masks be it whatever

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how they all work together because  sometimes they work against each other

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and also you've highlighted another property  whereby, the introduction of far UVC would

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have wide ranging properties for example. If you recent research paper has shown that it's killing bacteria to that degree.

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And will help to prevent other germs that might be floating around

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and also possibly other viruses and bacteria that  might cause future pandemics, so it's not something

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that would just help us with this pandemic  it would help us, it would have far-reaching,

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wide-ranging properties. For sure, I mean if  we think back two years, nobody expected Covid

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to happen or to be what it's what it's been, it  caught everybody a little bit up by surprise,

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the west in the western world especially  governments that had pandemic plans in in pro that

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or that that had worked on and published before  they they didn't seem to follow them properly one

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minute they're saying it's not not an airborne  virus next minute it is by that point everybody

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has already moved moved around they weren't  wearing masks and it's spread everywhere,

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would we be where we are now had we  had some kind of defense in place

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in January of 2020 and I don't know the answer,  maybe we would have been in a different space but

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you could envisage that if you had something like  far UVC that sits there passively in open spaces

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in public indoor spaces predominantly in  in in transit situations you would suppress

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a lot of infections across the board whatever they  are be they new or old, and if we suppress them,

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a bit like the masks do, if we suppress them less  people catch them if less people catch them we're

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able to handle it better and put other mitigations  in place so I think about things like far UVC

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as not so much something for Covid now but for

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Covid 3.0 that comes along later, or some other  pandemic that we haven't thought about yet,

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I think it's really important for 3.0 or future  pandemics whatever they may be, but I think it's

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also important for Covid, because Covid just has a  propensity to cause such a huge amount of chronic

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disease when you're looking at long Covid  figures, up to 30% of people that catch Covid

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are going to end up with long Covid if they're  unvaccinated, and that best research preliminary

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research is showing that vaccination will reduce  that by 50% but 15% is still a very high number and

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then we're also seeing organ damage possible organ  damage with people that are even asymptomatic now

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Professor banerjee in a previous episode talked  about research that he'd done to show that so I

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think, this is the whole point of this program we  need bits of risk reduction technology whether it

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be vaccination whether it be for UVC, whether it  be air filtration and ventilation all working in

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tandem to keep us safe, and so that we can get back  to normal life safely I think that's what we need

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I think you're right and I find it kind of bizarre, that Western governments, European

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governments, governments in other countries spend  so much money on things like defense, which I

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think is necessary, but we don't seem to do the  same thing in defense for health. Yes and this

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is when we see the economic cost that when we get  it wrong, like for Covid, the economic costs of that

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if we had done something and invested some  money early and been more cautious before

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and more prepared, I think is the better word,  I think things would look very different so,

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so if moving forward for continuing because  it doesn't look like it's going to go anywhere

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unfortunately at least not in the near term and  whatever comes next I think building in engineered

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passive solutions is really the best way to bring  people back to a normality of life that they want,

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whilst not losing the advantages of

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some of the more visible protective measures  that have been used in the past two years

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yeah, yes, so we could, there still might  be instances where we need to use masks

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but that would be reduced if we had far  UVC technology and air filtration, people

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were adequately vaccinated, all of that working  in tandem. Is that what you mean? That's exactly

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what I mean. I mean having far UVC there  for the vast majority of people might mean that

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people don't have to wear masks frequently and  those people that do, are the ones that have have

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more significant concerns, but the people that that  sit there now and are worried about their neighbor

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who's maybe not being as cautious as them they  can get some reassurance that far UVC is picking

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up the slack let's put it that way and I   think that make it will make everybody safer,

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Yeah, and I think you actually bring to mind an  important point because if you take like

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kids under the age of two, it's really difficult to  get them to keep a mask on and elderly people that

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suffer from dementia, or people with learning  difficulties. Very difficult to keep masks on

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them. So if we had far UVC lighting in those  environments it would really reduce their risk

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and the risk of those around them. Yes absolutely  it's it's a tool that's so useful in many

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contexts right okay you've answered a lot of my  questions which is fantastic so one that sprung

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to mind is what is the speed and distance that far  UVC would work for example how far would I need to

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sit from an infected person say if we were in a  restaurant and I had a friend who was contagious

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with SARS-CoV-2 and I didn't know it and we had  like a far UVC light shining on us from above,

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illuminating the restaurant so how close would  I need to be or far would I need to be from that

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infected person with the far UVC light shining  on us for me not to be infected by their aerosols?

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That is a hugely complicated question to  ask, because there is no one answer and

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and that's where the reality of how technologies  interplay with the real world, exhibit themselves.

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So right now most of the lamps are working to  the current threshold limit values that

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exist and that is 23 millijoules, per centimeter  squared of of energy in an eight hour period

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so you can pretty much do the math on that  and work out that you're just shy of about

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three millijoules per centimeter squared  so that's that's energy so we're spreading

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energy over a small area, and that that is what  the limit sort of tells us at that at those

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limits if you're sitting opposite somebody in a  restaurant and the airflow isn't in your favor

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all far UVC would do is reduce the concentration  that you get. So think of it a bit like a mask,

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now if you were closer to the lamp, you would  get more intensity. You might go above the

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guidance level but then you would kill more, more  quickly, if you were further away you'd kill less,

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If you're in a shadow, and the lamps above you  and you accidentally cause a shadow to be there

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the light can't hit it. So it's only as it's only  as effective as the amount of light it can see,

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and this is where real world implementations  are a problem, because if you think about

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HVAC systems they circulate air very  commonly, they circulate air around a room,

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so they might move the air closer to the  lamp and then blow it back around again

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and then it blows in your face. If it's got less  concentration of virus there that's a good thing

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for you, but I don't think that anybody can say  that you can kill all of the bugs that are coming

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out of a friend's mouth if you're sitting  there at a table at a restaurant and I don't

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think we ever can, and that then creates  its own question about risk now some

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companies have have considered whether  having much higher intensity

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far UVC sources in between people, almost like  a curtain if you like, could be a much

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higher power and because you're not in this, in  that illumination field you would kill more bugs

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and I think that could work too and that would  reduce it again a bit more still. But the idea

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that we can reduce it to zero I think is highly unlikely but you could reduce it to sub

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threshold infection levels or comparable levels to  what you'd get outside which is pretty much what

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the experiments in the UK's recently found so it's  a bit like what we've been talking about earlier

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we need this I call it 360 degree risk reduction  pandemic mitigation and other people have called

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it kind of a swiss cheese thing layer thing so you  need bits of everything so if you're sitting in

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that restaurant you want to know that you want  to educate that population to get vaccinated

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because that reduces your risk absolutely you  want an air filter or air ventilation a well

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ventilated environment because that would remove  more you want people to test before they come

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if you say that person who I'm sitting next to or  other people in the room might have gone to a big

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football match or an indoor concert you'd want to  encourage them to test themselves before they put

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themselves back into an indoor environment with  others, that would reduce the risk and then you've

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got far UVC lighting which will reduce the risk  down further so it's that whole layered effect

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of risk reduction that we need to educate the  population about so that they get on board with

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doing it so they can get back to some form of safe  normal life that's more or less what you're saying

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really absolutely I mean I think about cars, when  you drive your car hey you wear a seat belt so if

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you do get in a crash you don't go through the  windshield, you make sure that your brakes work

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so that you can stop if someone walks out in front  of you so you don't hit them, you make sure that

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that you can see through the  windshield, so you're not driving blind.

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You don't drink and drive. All of these things all  work together to improve the safety for all of us,

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both the person that's in the car and the person  that is on the street, and take any of those out

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of there and you increase risk so the important  thing is to understand how the risks work with

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each other the interesting one that you that  you mentioned was far UVC and ventilation,

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so this is a really key part of the equation  is if you get the ventilation profile

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wrong. You reduce the effectiveness of  the far UVC rather than increase it, so

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I actually think that in areas where airflow  can't be removed in a good way quickly,

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in a meaningful way quickly, something like far  UVC is a really good thing to put in place.

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So I have a colleague she does a huge  amount of advocacy for long-term care

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and many of the long-term care buildings are are  kind of old and don't have good ventilation so if

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you're thinking about some of those spaces they're  perfect candidates for things like far UVC because

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they would just sit there passively and that air  that's circulating naturally through the room

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would be somewhat sterilized and  that's the kind of thing where where

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where we really need to have to think,  but it's like everything whenever you install

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something if you get some electrical work  done, you make sure that the electrician

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tests the installation before you go and start  switching things on so it's safe, so I think the

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same is true when you install far UVC. The mistake  would be just to run down the store, get a lamp,

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stick it on the ceiling and assume it's going to  work the way you think it is. That's the same with

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everything. That's such an excellent analogy  you gave. The car and excellent examples there

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with long-term care and where far UVC could be so  useful. I think for me this this whole series is

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important so that the public can be educated and  demand the technology and then we need Government

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setups really nationally and internationally  where people are trained we have trained engineers

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trained that can go around and educate people on  how to facilitate these setups correctly I think

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there needs to be a whole organizational network  to put this technology in place in my opinion,

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I mean I could say it now  if you go back some many decades

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you find much more common reference to  something called public health engineering,

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and that doesn't seem to be something that we  spend as much time thinking about these days.

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We think about public health and we think about  engineering but those two things intersecting,

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I think is where the next 20 years needs to be. It  needs to happen now in my opinion. I mean, I' m not

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saying that not saying that. What I'm saying is  you know, it's something that we should be doing. Yes!

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And the field needs to establish itself so that  we understand that okay you can reduce infection

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by changing the way people walk, so rather than  have them snake next to each other so they're

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cross pathing all the time make them go around  a different slightly different way and that then

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changes the dynamics of the situation and the same  is true with far UVC you know, I think Professor

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you Kirk and Jose Jimenez have really pointed  out that we need science and then scientists and

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engineers to be more involved with Public Health  because how the virus and and other pathogens such

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as bacteria act in the environment is really your  domain, the physics of the environment and how

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things like aerosols light etc interacts is your  expertise and and as medics how the bacteria and

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viruses work within our body is our expertise. So  the medics have done fantastic jobs, but it's only

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half the solution to us living safely. I think  you've really highlighted that today, for sure

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okay so we're running out of time and there's a  couple of important questions I wanted to ask so

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currently far UVC bulbs are expensive  partly because there isn't a demand due

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to the lack of knowledge about the technology  and partly because there isn't an LED equivalent

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when do you foresee an LED version of the bulb  being made available so that they can mass

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so they can be mass produced  for say our homes for example so

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first thing is if we roll back a year or two  the lamps are what then were significantly

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more expensive than they are now so there  are a lot more vendors on the market a lot

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more people playing in this game I think we're  still not getting the message out well enough

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as to the fact that they could be useful, and  I think in some people's minds they've they've

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they've already moved on, and so they're not  investing the same kind of considerations they

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were before they feel they've got their solutions  and that's that and I think that's flawed

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but I think we're much more in a zone  now where we're in the comparable to

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water sterilization cost range so that is still  expensive relative to your standard kind of

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energy efficient light bulb that you that  you're sticking to your fitting at home

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and I'd say we're still some ways away from  that the LED thing is interesting it's easier

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to make LEDs for longer wavelengths and this  is fundamentally where it becomes a technology

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problem and it might well be that you can make  far UVC LEDs and there are people that do work

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on this already, but their efficiency and their  intensity, their output, isn't necessarily very high.

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So I think if you really wanted to  speed things up you want somebody with  sufficient

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money to scale the technology that already  exists, so that it's cheaper and can be

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mass produced more quickly and whilst there are  big companies involved, what you need is you

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need you need an Elon Musk or somebody like  that to come out and pump up a lot of money

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to make it, so and then it will take off, and  then the market will do the rest because none

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of this stuff is very hard to do. It's just that  it will scale to demand, so demand has increased

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competitors exist prices come down already  price will continue to come down you know

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if we if we went back and think thought about how  much cell phones cost when they first come out

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and now think about that you can buy them in  almost disposable, that that cost can really

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change quite rapidly so I think it's less about  waiting for the leds although the LED is a kind

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of neat solution and they will come in time I  think it's more about getting the message out

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there to the people that can influence purchasing  power and then the market will do the rest.

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That's an excellent answer, Kirk. Thank you for  that.

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You talked in the beginning about how the research  you and your team did enhance the research that

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Professor Brenner did, in Colombia. Could you talk  a little bit about that what you've done? Sure,

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so in 2018 and then in 2020 the group in Colombia  made some experiments with a benchtop chamber

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this is before they managed to get access to  the one in the UK which I spoke about earlier

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and this benchtop chamber had sort  of an inlet and an outlet and blew

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some some air through it that had been seeded with  coronavirus it was a different human coronavirus

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but it's very much representative and the way  this this system was set up it had a kind of

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window and a lamp on the outside and some  structures and various things were happening

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and they made a rough approximation about this  is the size of the chamber this is the speed of

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the air and then when they they looked at their  results at the end for the amount of illumination

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and the reduction in the infectiousness of of  the virus that was in the air so how many virions

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have been killed effectively? They made in the sum  they made an estimation of what the susceptibility

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of the coronavirus was to far UVC but it  neglected a lot of things, because when you blow

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through for a tube you get drag at the sides so  that means it slows things down, so if any virus

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that's near the edges is staying in the light  longer and actually the virus that's in the middle

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being blown through the middle moves the quickest  so stays in the light comparatively less time

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and then there's shielding effects and distance  effects that they hadn't really accounted for so

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we were able to help them with that and actually  showed that their susceptibility was about half of

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what it really was, and that was the key finding and we've had a couple of papers

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out with them on on that topic specifically so it  shows that actually for coronavirus you know human

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coronaviruses far UVC is exceptionally useful  and coronavirus is very sensitive now you'll

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you'll remember I talked about the fact that  the far UVC couldn't make it through the skin,

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because these viruses and these other pathogens  float around in the air they're so small.

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Those far UVC photons light rays  they're able to get absorbed by them and

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fundamentally that's what this thing  does and the susceptibility is really a measure of

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how well far UVC or any other light how good  it is at killing that particular pathogen

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for particular energy in particular the amount of  time or area great well we're practically out of

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time and I just want to thank you, Kirk, for your  contributions today. I really wanted to inform the

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audience of this amazing technology that has  a scope to change all our lives and help us to

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live safely with this coronavirus and you have  really facilitated that. Thanks to you and your

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colleagues for all the marvelous work that you're  doing to keep us safe. That's no problem,

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You're welcome, I mean, I think there are lots of  people across the world doing lots of great stuff

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and we actually talk to each other which  is a good thing, because that communication

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is really a key thing sharing  the results will mean that we're quicker

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to respond to threats. Very much. I think the most  successful aspects of the pandemic has been the

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collaboration and the openness of science that's been facilitated.

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Thanks for listening to this week's episode of  COVID-19 The Answers. If you enjoyed the episode

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please SUBSCRIBE, RATE and REVIEW and do visit  our website kojalamedical.com/COVID19theAnswers

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