Known as the American Ripper, the first and most prolific serial killer, and the architect of the Hotel of Horrors, Hotel Hell, The Killing Castle, The Murder Mansion, and many others, H.H. Holmes was a murderous deviant doctor with a sick drive for blood. Or was he just a white collar criminal who's cunning breadcrumbs finally caught up to him? And what about his connection to Jack The Ripper?

Listen as the Ladies of Scarlet discuss Dr. H.H. Holmes and his half decade of destruction during Chicago's boom in the late 18th Century.

Sources: America Ripper from The History Channel

Wikipedia

New England Historical Society

Murderpedia

All That's Interesting

H.H. Holmes America's First Serial Killer Documentary