What can a cancer researcher teach us when he suddenly finds himself sitting in the patient chair?
Larry Coffer spent more than 20 years at MD Anderson Cancer Center supporting ovarian and breast cancer research, helping teams develop treatments and improve outcomes for patients. Long before his own diagnosis, cancer shaped his life through his stepfather’s battle with colon cancer. That experience inspired a career dedicated to helping others. Then, while training for a marathon, a routine physical revealed a rare cancer called extramedullary plasmacytoma. What began as a standard checkup quickly became a life-changing journey.
Larry shares what it was like to move from researcher to patient, receive treatment at the institution where he built his career, and navigate the uncertainty that comes with a rare diagnosis. He opens up about the emotional toll of cancer, the importance of leaning on friends, family, faith, and community, and how running helped him process the experience. He also discusses his work as a stem cell donor and advocate, helping others understand the life-saving impact of bone marrow and stem cell donation.
Larry’s story is a reminder that a diagnosis does not define who you are. With support, purpose, and hope, it is possible to keep moving forward one step at a time.
Highlights:
· How a routine health screening uncovered a rare cancer with no warning signs
· What changes when a cancer researcher becomes a cancer patient
· Why support systems matter even for the people who seem strongest
· How running, faith, and community can help during treatment and recovery
· What stem cell donation really involves and why more donors are urgently needed
Mentioned Resources:
CanCare- www.cancare.org
Larry’s Marathon Fundraiser for CanCare - https://fundraisers.hakuapp.com/larry-coffer
About the Guest:
Larry Coffer is a plasma cell cancer survivor, cancer researcher, stem cell donor, and marathon runner. For more than 20 years, he has led groundbreaking research at MD Anderson Cancer Center focused on ovarian and breast cancer. Then a routine physical before a marathon changed everything. Larry completed 20 rounds of radiation and rang the bell in January 2026. His running community has a special connection to CanCare, a full circle moment. Larry shares what happens when the science becomes personal, and what he found on the other side.
Love the podcast? You’ll be moved by the book. The Hope in the Face of Cancer book shares inspiring, real stories from survivors, caregivers, and healthcare heroes. Raw, uplifting, and full of heart—for anyone seeking hope and connection. Get your copy: cancare.org/hopebook.
About Our Host:
Darcie Champagne Wells is the President and CEO of CanCare, Inc., a nonprofit dedicated to providing support to the cancer community by pairing cancer patients with survivors. Since joining in November 2020 as the third President & CEO, Darcie has driven significant growth, increasing one-to-one support matches by 45% and healthcare referrals by 66%. In 2022, she initiated the Impact Acceleration Initiative to further expand support for cancer patients and caregivers. Her leadership has earned her recognition as a “Most Admired CEO” and “Woman Who Means Business” by the Houston Business Journal, and national “Fundraiser of the Year” by RAISE. Darcie holds a BS in Business Administration from Louisiana State University and an MBA from the University of Houston.
https://www.cancare.org/
https://www.facebook.com/CanCareInc
https://www.instagram.com/cancare_inc
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📖 Enjoy the podcast? You’ll love the book.
Check out our book, Hope in the Face of Cancer—a powerful collection of real stories from survivors, caregivers, and healthcare heroes. It’s uplifting, raw, and full of heart. Get your copy at cancare.org/hopebook.
