Tune in to our podcast for an in-depth discussion on immunotherapeutic strategies for Acute Myeloid Leukemia (AML). In this episode, we feature Dr Sarah Tettamanti, a senior scientist at the Fondazione Tettamanti Research Centre in Italy, who shares her expertise on CAR T-cell therapy for AML.

With host Dr Sarah de Vlieger, they examine the progress and challenges in treating AML with CAR T-cells, the balance between treatment efficacy and safety, and the potential of combining CAR T-cells with other immunotherapies.

The episode also covers the complexities of the tumor microenvironment in AML, antigen selection for targeted therapy, and the design of smarter CAR T-cells. Sarah discusses the future of CAR T-cell therapy, including fourth-generation CAR T-cells and the role of natural killer cells in AML treatment.

Host: Dr Sarah de Vlieger

Guest: Dr Sarah Tettamanti

This episode is part of a series recorded at the joint EHA-EBMT 6th European CAR T-cell meeting in Valencia in February 2024, more podcasts will be available in the future. Stay tuned!

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