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Methylation: A Primer to My Interview With Dr. Albert Mensah
11th February 2022 • Root of the Cause Radio • Root of the Cause Radio
00:00:00 00:16:00

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Today I’m doing a solo episode covering key concepts I discuss in my upcoming interview with one of the leading experts on methylation today, Dr. Albert Mensah. Dr. Mensah was in the game many years prior to the word methylation even becoming part of the functional medicine vernacular. He mentored under Dr. William Walsh, who started doing groundbreaking work on methylation in the mental health sphere decades before MTHFR became a trendy buzz term and years before methylation was at all talked about outside of academic circles. Dr. Mensah is part of this lineage of the great pioneers in the field of methylation research, and as such, you’ll see that his knowledge in this area knows no bounds. With that said, I felt that doing a solo episode to provide some background information and a better understanding of some of the advanced concepts we discuss would be of value. Look for my three-part interview series with Dr. Mensah, which will be released in the coming weeks. 

2:16 - Selective serotonin re-uptake inhibitor SSRI physiology 101

6:04 - How homocystein is biochemically made

7:30 - Methionine converting to S-adenosyl-L-methione (SAM)

8:03 - SAM converting to SAH

9:02 - The SAM to SAH ratio

9:55 - The methylation misconceptions of folate 

12:14 - Selective serotonin reuptake enhancers 

13:02 - gene polymorphism (SNP) 101

13:41 - Glycine in the context of methylation

Methylation Pathway Visual Aid 

SSRI 101 Visual Aid


Email ROTC@rootofthecause.net with questions or requests for future episodes.

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