There's a particular kind of exhaustion that comes from trying everything, therapy, medication, every piece of advice, and still not finding relief. This episode of The Healing Mindset speaks directly to that exhaustion. Host Nazish talks with Dr. Aubrey Verdun, a double board-certified anesthesiologist and founder of Freedom Ketamine Treatment Centers, about ketamine therapy for treatment-resistant depression and PTSD, and what the safety and process actually look like under proper medical care.
Dr. Verdun addresses the stigma around ketamine directly, explains how it works differently from traditional antidepressants, and walks through what a supervised treatment series actually involves, including the ongoing therapy support that makes it more durable. This conversation offers grounded, medically informed hope for people who feel like they've run out of options.
About the Guest:
Dr. Aubrey Verdun is a double board-certified anesthesiologist and pain management physician with over 20 years of experience. He is the founder and medical director of Freedom Ketamine Treatment Centers, a practice offering evidence-based ketamine infusion therapy for treatment-resistant depression, PTSD, and related conditions.
Key Takeaways:
- Ketamine, when administered by trained medical professionals in a clinical setting, has a strong safety profile, distinct from its reputation tied to unregulated recreational use.
- Ketamine works through a different pathway than traditional antidepressants, targeting glutamate transmission rather than serotonin or norepinephrine reuptake, which is part of why it can help when other treatments haven't.
- A typical treatment series involves multiple infusions over several weeks, followed by occasional maintenance sessions, rather than a single one-time fix.
- Pairing ketamine treatment with ongoing talk therapy tends to produce more durable results than the infusions alone.
- If a full series is recommended, completing it matters. Stopping partway through, similar to not finishing a course of antibiotics, may limit how effective the treatment can be.
Connect With the Guest:
Website: https://www.freedomketaminecenters.com
Episode Chapters:
[00:00] Welcome to The Healing Mindset — meeting Dr. Aubrey Verdun (approx.)
[03:00] Common misconceptions about ketamine and where they come from (approx.)
[08:00] Why ketamine works through a different pathway than traditional antidepressants (approx.)
[14:00] What it looks like when someone first considers this treatment (approx.)
[19:00] Walking through an actual infusion session (approx.)
[24:00] Why pairing treatment with therapy matters for lasting results (approx.)
[28:00] What to do if progress feels uncertain partway through (approx.)
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