When God asks Cain, "Where is your brother?" Cain responds in an arrogant manner and basically tells God, "If you're God, you should already know!"

Then God responds, “Listen; your brother's blood is crying out to me from the ground! And now you are cursed from the ground, which has opened its mouth to receive your brother's blood from your hand. When you till the ground, it will no longer yield to you its strength; you will be a fugitive and a wanderer on the earth." (Gen. 4:10-12) 

And he said what hast thou done?

I know what thou hast done; thou hast slain thy brother, thine own, thine only brother, a holy, righteous, and good man, who never gave thee any offence, or any just occasion for shedding his innocent blood. This God spoke because He said as knew what Cain had done. God was still trying to impress his mind with a sense of the evil, and to bring him to a confession of it, before the sentence was passed, that it might appear to all to be just, and of which there was full proof and evidence, as follows: the voice of thy brother's blood crieth unto me from the ground!

Society continued to degrade into depravity. So much so, that Cain's descendent, Lamech, committed murder as well. He tried to pass it off as if he was innocent.

Bottom line, when God cursed the ground, it was on the ground, not on Adam. But when Cain committed his sin, it brought a curse on HIM.

What could the godly line of Seth—narrowed eventually to only Noah and his family—do against a culture so depraved that God would eventually decide to utterly destroy it?

That's what we will be studying as we move forward.

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