The Nitric Oxide Truth: Why Your Supplements (and Toothpaste) Might Be Working Against You

Biochemist Dr. Nathan Bryan has spent 30 years researching nitric oxide (NO) — a molecule he calls the earliest event in the onset of every chronic disease.

But despite all the supplements, powders, gummies, and health claims surrounding nitric oxide, much of what people are being sold isn't backed by the science.

In this episode, we sort the real science from the Instagram-ad noise and explore what nitric oxide actually does, how your body makes it, and the everyday habits that may be shutting down your body's own production.

In this episode we cover:

• What nitric oxide actually does and why loss of NO production may come before chronic disease, not after
• Why many arginine and beet supplements don't work the way people think they do — including the surprising gummy trick that can completely inactivate active ingredients
• The everyday habits that may be shutting down your body's own nitric oxide production, from oral health products to medications and other lifestyle factors
• Hydroxyapatite, what it is, and why Dr. Bryan uses it in his fluoride-free toothpaste — along with the surprising connection between your mouth, inflammation, and heart health
• Why sunlight, vitamin D, and nitric oxide are connected — and why you can't necessarily out-supplement the sun
• A simple nasal-breathing practice that can support nitric oxide production for free
• How topical nitric oxide helped heal a wound doctors had called “unhealable”

Dr. Nathan Bryan is a biochemist and one of the world's leading researchers on nitric oxide. His work explores the role nitric oxide plays in cardiovascular health, mitochondrial function, aging, and chronic disease.

Find Dr. Nathan Bryan at N101.com.

His book, The Secret of Nitric Oxide: Bringing the Science to Life, is also available now.

Instagram: @drnathansbryan

X: @DrNitric