For nearly two decades, HRT carried a shadow. After the early interpretation of the Women’s Health Initiative study in the 1990s, the message across medicine was clear: hormones were dangerous.
Millions of women were left in a “hormone desert,” navigating menopause with little more than advice to just grin and bear it.
But recently, the initiative was reassessed, and the data tells a far more nuanced story.
HRT may play an important role in improving symptoms and supporting cognitive and mental health during midlife. The problem is: the mindset around HRT may now be swinging just as dramatically in the opposite direction.
Scroll through social media, and you might believe every woman should be on HRT.
Brain fog, mood swings, poor sleep, weight changes, and hormones are increasingly framed as the universal solution.
But menopause isn’t a single experience, and hormone therapy isn’t a single intervention. Some women benefit enormously from it, while others may not need it at all.
So how should women and their physicians approach hormone therapy? What do we know about HRT and its effects on mental health?
In this episode, I’m joined by the physician president of Obstetrics and Gynecology Associates and menopause-society certified practitioner, Dr. Krista Olsen.
We explore how the medical understanding of HRT has evolved and what the evidence actually says about mood, cognition, and mental health during menopause.
Things You’ll Learn In This Episode
From common treatment to medical taboo
The Women’s Health Initiative reshaped women’s medicine almost overnight. How did its interpretation leave an entire generation of women navigating menopause without support?
HRT isn’t a one-size-fits-all solution
Hormone therapy is increasingly being framed as a universal solution for midlife women. When everyone is told they should be on HRT, what important clinical questions risk getting overlooked?
Hormone depletion vs. hormone fluctuation
Many of the most disruptive symptoms of perimenopause come from dramatic hormonal swings, not simply low estrogen. How does that distinction change how clinicians approach treatment?
Symptom-based care matters more than hormone levels
In an era of hormone testing kits and online wellness protocols, many women are being told to “optimize” their hormones. But what happens when treatment focuses on numbers instead of lived experience?
About the Guest
Dr. Krista Olsen is the Physician President for Obstetrics and Gynecology Associates and a Board Member of i-Health. She is also a Menopause Society Certified Practitioner in 2024. After majoring in Biology with a secondary concentration in Scandinavian Studies at St.Olaf College in Northfield, Minnesota, Dr. Olsen attended the University of North Dakota School of Medicine in Grand Forks, North Dakota. She completed her OBGYN residency at the University of Minnesota in Minneapolis, Minnesota. She is certified by the American Board of Obstetrics and Gynecology and the American Institute for Ultrasound in Medicine. Dr. Olsen is also a certified physician coach working with physicians across the country on weight loss and goal setting, as well as bringing these skills into the clinic setting with her patients. To learn more, go to https://obgynpa.com/.
About Your Host
Hosted by Dr. Deepa Grandon, MD, MBA, a triple board-certified physician with over 23 years of experience working as a Physician Consultant for influential organizations worldwide. Dr. Grandon is the founder of Transformational Life Consulting (TLC) and an outspoken faith-based leader in evidence-based lifestyle medicine.
Disclaimer
TLC is presenting this podcast solely for information sharing. It is not medical advice or intended to replace the judgment of a licensed physician. TLC is not responsible for any claims related to procedures, professionals, products, or methods discussed in the podcast, and it does not approve or endorse any products, professionals, services, or methods referenced.
Work With Me
Learn More About My Soon-to-Launch Telemedicine Platform
Exciting news. My virtual medical platform is launching soon! If you’re looking for personalized, evidence-based care in allergy, immunology, and lifestyle medicine, stay tuned.
Visit drdeepa-tlc.org and click on “Learn More” to join the waitlist and be the first to receive updates about services, membership options, and launch details.
Precision care. Personalized guidance. Wherever you are.
Devotionals
Want to receive a devotional every week from Dr. Deepa? Devotionals are dedicated to providing you with a moment of reflection, inspiration, and spiritual growth each week, delivered right to your inbox. Visit drdeepa-tlc.org to subscribe for free.
Trauma Courses CTA
Ready to deepen your understanding of trauma and kick-start your healing journey? Explore a range of online and onsite courses designed to equip you with practical and affordable tools. From counselors, ministry leaders, and educators to couples, parents, and individuals seeking help for themselves, there’s a powerful course for everyone. Browse all the courses now to start your journey.
