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Lambert-Eaton Myasthenic Syndrome in Small Cell Lung Cancer — An Interview with Prof Ticiana Leal
Episode 521st September 2026 • Lung Cancer Update • Dr. Neil Love
00:00:00 00:54:35

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Featuring an interview with Prof Ticiana Leal, including the following topics:

  • Pathophysiology and clinical signs and symptoms (0:00)
  • Screening and/or diagnostic approaches (5:45)
  • Potential impact of available therapies for small cell lung cancer (SCLC) on paraneoplastic syndromes (7:36)
  • Key clinical trial data for amifampridine and practicalities of its administration (14:05)
  • Building awareness among patients, caregivers and the oncology community (22:37)
  • Role of pyridostigmine in managing Lambert-Eaton myasthenic syndrome (LEMS); potential integration of EMG (electromyography) into monitoring (25:35)
  • Case: A man in his early 70s who receives a diagnosis of limited-stage SCLC (LS-SCLC) with LEMS and undergoes treatment (27:41)
  • Case: A woman in her late 70s already diagnosed with LS-SCLC who is subsequently evaluated and treated for LEMS (37:55)
  • Current research and potential developments in the treatment of SCLC (48:32)

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