In recent years, American health care has become acutely aware of the importance of well-being for its workers. To address the mental stresses of health care, Chicago’s Northwestern Medicine established the Scholars of Wellness program, focusing on understanding what well-being actually means, and how it can be woven into organizational culture. In this discussion, Gaurava Agarwal, M.D., vice president and chief wellness executive at Northwestern Medicine and director of faculty wellness at Northwestern University, and Samantha Saggese, physician assistant of nephrology and hypertension at Northwestern Memorial Hospital, explain the difference the Scholars of Wellness program is making, and how it could be adopted for the benefit of hospitals and health systems across the nation.