The International Lymphatic Disease and Lymphedema Patient Registry & Biorepository plays a crucial role in advancing lipedema research and raising awareness about the condition. Overseen by the LE&RN Board of Directors and the Institutional Review Board of Stanford University, led by Dr. Stanley Rockson, the registry aims to expand our understanding of lipedema. Participation, particularly from women with lipedema, is essential to enhance the knowledge base surrounding this disease.