On today's Cannabis Boomer's Journal of News and Reviews in Cannabis Science, Dr. Alex Terrazas PhD gives his take on the latest findings in cannabis research.
But first. here is The Cannabis Boomer's top cannabis news story.
[0:0:18.69] The Cannabis Boomer, Alex Terrazas, PhD
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Two new European studies have found that cannabis-based treatments can effectively alleviate chronic low back pain, outperforming both placebo and opioid painkillers. The studies showed a cannabis oil blend containing THC, CBD, and other compounds reduced pain by around 30% compared to 20% for placebo. Importantly, the cannabis treatment had fewer side effects than opioids. While the cannabis product tested is not yet available in the U.S., the findings provide strong evidence that cannabis-based therapies could be a safer alternative to opioids for chronic pain management. However, experts caution that cannabis is not a panacea, and more research is needed. The lack of FDA-approved cannabis medications in the U.S. remains a barrier, frustrating patients seeking effective, non-opioid pain relief options.[0:1:22.82]] Grace And now the Cannabis Boomer reviews recent cannabis science publications.
[0:1:28.31] The Cannabis Boomer, Alex Terrazas, PhD
First up is The Acute Cardiovascular Response to Dynamic Exercise and Recovery Following Cannabis Use by Cheung and colleagues. This study examined the cardiovascular effects of cannabis use, both during and after exercise, to elucidate the combined effects of these two factors. The key findings were that smoking THC-predominant cannabis elevated post-exercise pulse pressure, and reduced septal isovolumic contraction time, indicating altered systolic function, but did not affect blood pressure or cardiac function during exercise. Methods used (brief): Within-subject design, participants inhaled cannabis with high THC (smoked or vaporized) or high CBD (vaporized), and cardiovascular measures were assessed at rest, during 20-minutes of maximal exercise, and during recovery.The findings demonstrate the nuanced effects of combining cannabis use and exercise on cardiovascular physiology, which is important for understanding the potential risks and considerations for individuals engaging in both activities. Methodological shortcomings (brief): The study had a relatively small sample size (n=14 for some measures, n=22 for others), and did not include a placebo condition, which could have provided more insight into the specific effects of cannabis.
The next article today is The Current State of Unapproved Cannabidiol Product Use in Children by Cowell and others. This review article discusses the current state of unapproved CBD product use in children, including its pharmacology, legal and regulatory factors, usage patterns, efficacy data, safety concerns, and recommendations for clinicians, public health officials, and researchers. Key findings: CBD has therapeutic benefit for the treatment of seizures associated with various epilepsy syndromes in children, but data are lacking related to the use of CBD for other indications in pediatric patients; despite this, the use of CBD products as a complementary treatment for various conditions in children continues to increase. This is a review article that summarizes the current literature on the use of CBD in children and adolescents. It is imperative that those involved in the care of children and adolescents are well informed with current information related to CBD use in pediatrics, and recommendations are provided to effectively manage the use of unapproved CBD products in the pediatric population.
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