Artwork for podcast Becoming Natural
Why Spit is Surprisingly Helpful: Saliva Actually Supports a Healthy Body
Episode 85 • 6th October 2026 • Becoming Natural • Penelope Sampler
00:00:00 00:42:09

Share Episode

Shownotes

The benefits of saliva are easy to miss—until you know how many jobs saliva actually has!

Read the full episode + resources: https://becomingnatural.com/benefits-of-saliva/

In this episode, we look at how saliva helps you taste, chew, swallow, and begin digestion, while also buffering acids, supporting enamel remineralization, and helping regulate the oral microbiome.

We follow the surprising nitrate-to-nitrite pathway that connects bacteria on your tongue with nitric oxide and blood-vessel function. We also look at persistent dry mouth, why medications and mouth breathing matter, and when it deserves more attention.

And we explore the unusual Gospel passages where Jesus used saliva in healing and what people in the ancient world understood about it. By the end, you may never think of spit as “just spit” again.

In This Episode You'll Learn:

• How saliva supports enamel and helps buffer acids in the mouth

• How bacteria on the tongue help convert nitrate to nitrite as part of the nitric-oxide pathway • Why medications, mouth breathing, and other factors can contribute to persistent dry mouth

• Why saliva appears in several Gospel healing accounts and how people in the ancient world understood it

Keep Listening Fluoride Skeptics: Hidden Truth Makes for a Safe and Healthy Life https://becomingnatural.com/fluoride-health-concerns/

This episode is educational and not medical advice. If dry mouth sticks around, or it started after a medication change, bring that to a dentist or the prescriber.

Transcripts

Speaker:

Moms have been using one very questionable cleaning product for generations.

Speaker:

No bottle. No spray. Usually applied directly with your hands.

Speaker:

And now I have questions. Is it really a cleaner? Does it eradicate 99

Speaker:

9% of germs? Or is there actually more biology happening there than we know

Speaker:

Is this cleaner Becoming Natural approved?

Speaker:

We’re about to find out.

Speaker:

Before we get into today’s episode, I wanted to take a few extra minutes and

Speaker:

fill you in on what Becoming Natural is becoming—and, with that, where I’ve been

Speaker:

If you listen regularly, you’ve probably noticed I’ve missed a few episodes over the summer

Speaker:

Becoming Natural is very much alive. In fact, behind the scenes, I

Speaker:

ve probably been working on it more than ever. Around the clock

Speaker:

actually

Speaker:

This summer, I decided to build an entire operating system for the podcast—something that could

Speaker:

help me manage research, summaries, the future website, downloads, analytics, SEO, and all the other things

Speaker:

I didn’t even know existed when I started. I just knew that I loved researching

Speaker:

and writing, but the time it took for the admin tasks was time I could not

Speaker:

sustain over time

Speaker:

I just want to read and write.

Speaker:

Apparently, at this stage of my life, I have also become someone who builds

Speaker:

operating systems and talks about code. Which is

Speaker:

comical

Side note:

I actually took a computer science class in high school. For

Side note:

my final project, I built a little matchmaking program in DOS. Ten questions for

Side note:

the boys, ten for the girls, compare the answers, and voilà—a match

Side note:

My teacher, who was very smart but clearly lacked

Side note:

vision for my future empire, made fun of the

Side note:

project

Side note:

I could have invented Match.com, my friends.

Side note:

he apparently thought I was just a silly girl making boys and girls match up on a computer

Side note:

Missed opportunity, sir. Sure wish I could tell him now.

Side note:

Anyway…

Side note:

Building all of this has been fascinating, but the learning curve has been massive. I actually

Side note:

I have built things, lost things, recovered things, rebuilt them better, celebrated way too

Side note:

late at night because I finally figured something out…and then occasionally woke up

Side note:

the next morning to discover that part of my beautiful little puzzle had disappeared

Side note:

again

Side note:

Some days it has felt like a roller coaster.

Side note:

And the perfectionist in me has had a hard time moving forward when I

Side note:

know the pieces behind an episode aren’t working the way I want them

Side note:

to

Side note:

There has been something

Side note:

underneath all of that

Side note:

though

Side note:

When I started this podcast, I thought a lot of my purpose would be

Side note:

talking about Crohn’s disease, my healing, and what I learned through that experience

Side note:

That was what I knew.

Side note:

And I am still incredibly passionate about helping people walking through Crohn’s and chronic illness

Side note:

But I’ve realized my story is bigger than Crohn’s.

Side note:

The more I study, the more fascinated I become with how our bodies were designed

Side note:

how our ancestors used what was available to them to care for their bodies, what

Side note:

Scripture teaches us about stewardship, and how connected our physical, emotional, and spiritual health really

Side note:

are

Side note:

I’ll start researching an episode thinking I’m going to learn about something, and before

Side note:

long I’m sitting there with my mouth wide open amazed by what I’m learning

Side note:

myself

Side note:

The human body is incredible, and apparently this podcast is taking me somewhere I didn't expect to go

Side note:

The connection between our bodies and the earth is real—not in some mystical sense, but in

Side note:

the very practical reality that the same God who created us also created the world we live

Side note:

in

Side note:

Our bodies respond to light and darkness. They depend

Side note:

on minerals. They interact with plants, food, microbes, seasons

Side note:

sleep, movement, stress, and the environment around us every

Side note:

single day

Side note:

I keep finding myself amazed by those connections.

Side note:

I am learning right alongside you.

Side note:

Lately I've been thinking a lot about why I'm doing this

Side note:

in the first place—and what really belongs under Becoming Natural

Side note:

This has become my checkpoint:

Side note:

Becoming Natural follows the tension between what we’ve been told, what ancient people observed

Side note:

what modern science can actually explain, and what the body has been showing us all

Side note:

along

Side note:

We look for the surprising connections between physiology, nature, everyday exposures, traditional wisdom, and

Side note:

Scripture—the kind of connections that make you stop and say, “I had no

Side note:

idea

Side note:

Because the closer I look at the body and the world around us, the more intricate the design becomes

Side note:

That has become the thread I come back to every episode.

Side note:

Does this help us understand the body better?

Side note:

Does it make us look more carefully at something we’ve accepted without much thought

Side note:

Does it connect what people observed long ago with something science can now help explain

Side note:

And does it leave room for me to ask what Scripture has to say without trying to force Scripture into a science lesson

Side note:

If it does, it probably belongs here.

Side note:

A few years ago, after what I called my “year of no”—a year

Side note:

when I desperately needed to simplify my life and find some sanity again—I

Side note:

went live on Facebook and announced that I was entering my “year of yes

Side note:

Mostly to hold myself accountable. But I remember very clearly sitting in my

Side note:

car on a rainy day in the McDonalds parking lot making my declaration

Side note:

I said I was going to say yes to doing hard things and accept hard things if I believed that was what God was asking me to do

Side note:

The discerning part alone can be hard.

Side note:

I also highly recommend being very specific when you make statements like that to the Lord

Side note:

My husband and I had done something similar years earlier after hearing a sermon about growing your faith

Side note:

We actually prayed for challenges that would grow us.

Side note:

I know.

Side note:

Bold choice.

Side note:

What followed included severe health struggles, sepsis, enormous

Side note:

life changes, and eventually my husband leaving his

Side note:

job and our family moving to another state

Side note:

So…be careful what you pray for.

Side note:

But our faith grew.

Side note:

Our marriage grew.

Side note:

And we learned something through those years that has stayed with us

Side note:

even when we had absolutely no idea what was happening, God had

Side note:

us

Side note:

We had prayed for growth. I don't think either of us pictured it arriving quite like that

Side note:

Years later, when this podcast unexpectedly came into my life, I knew saying yes meant sharing more openly about

Side note:

my faith, my healing, and some of the things our family had witnessed that I can only describe as

Side note:

miracles

Side note:

I even talked with my husband about the possibility that doing that might bring some spiritual resistance with it

Side note:

Again.

Side note:

He was still in.

Side note:

He’s always in.

Side note:

I just like to run the big God matters past him before I dive in headfirst.

Side note:

What I didn't expect was how much growth would come with saying yes to this podcast.

Side note:

Since Becoming Natural began, our family has walked through challenge after challenge

Side note:

Nothing I need to unpack here today, but enough little things piling up

Side note:

that eventually you realize you’re not dealing with one paper cut anymore

Side note:

It’s more like a thousand of them, and at some point you start noticing a pattern.

Side note:

Growth by strength against resistance. Seems to be my life motto, actually.

Side note:

Through all of that, I kept coming back to something I wrote in my journal years ago when

Side note:

I was very sick, raising three little boys, and sometimes just trying to make it through the day

Side note:

I wrote

Side note:

Lord, use me and my words for Your purposes.

Side note:

Let my experiences help grow someone’s faith so my pain is not for nothing.

Side note:

Let my experience help someone trust You.

Side note:

Let me be a vessel.

Side note:

Let this be Yours.

Side note:

I read that prayer very differently now than I did when I wrote it.

Side note:

I have the privilege of hindsight now.

Side note:

Back then, I was in the thick of it.

Side note:

I was begging for healing while at the same time asking God to use what I was walking through for His purposes

Side note:

I don’t think I fully understood what I was asking.

Side note:

So yes, that is a big part of where I've been this summer.

Side note:

been creating, learning how to build things I never thought I would be

Side note:

building, designing the website that has been living in my head, and occasionally

Side note:

playing spiritual whack-a-mole—which, truth be told, has not always happened

Side note:

without tears

Side note:

And I’ve been reading a lot of Scripture.

Side note:

Partly because you are trusting me with some pretty big subjects.

Side note:

If I’m going to talk about the body, healing, history, natural living, faith, and what Scripture

Side note:

says about how we live and care for ourselves, I feel a responsibility to keep learning too

Side note:

I don’t want to repeat something just because it sounds good.

Side note:

I want to know where it came from and whether it’s true.

Side note:

When it comes to science, I want to understand the research well enough to explain it

Side note:

When it comes to history, I want to know what actually happened instead of repeating a story that has been passed around the internet a thousand times

Side note:

And when I bring Scripture into an episode, I want to be in the Word myself. I

Side note:

don’t want to grab a verse because it happens to fit what I already decided I wanted to say

Side note:

I've learned some pretty amazing things this summer, and God has not disappointed.

Side note:

I’m still here.

Side note:

Becoming Natural isn’t slowing down.

Side note:

I'm actually trying to build a stronger foundation underneath if the Lord's will is to do so and it grows and does

Side note:

something bigger. It can support that growth without me trying to hold everything all by myself with my hands. I just want

Side note:

to be faithful with the part that God has put in front of me and let him decide what comes after that

Side note:

And after that explanation of where I've been and what I've been doing all summer, today we are going to talk about

Side note:

spit

Side note:

Are you ready?

Side note:

Today we're talking about saliva.

Side note:

And I know. Very sophisticated.

Side note:

Stay with me, because I kept finding things that made me stop and say, 'Wait—saliva does that too

Side note:

I originally started looking into saliva because of dry mouth. That seemed straightforward enough. What causes it? Why

Side note:

do some people suddenly develop it? Are medications involved? Does menopause matter? Is it actually because we're dehydrated

Side note:

all the time, like every wellness article on earth seems to suggest? is our water actually truly hydrating

Side note:

us

Side note:

Dry mouth ended up being my way into a much more interesting question:

Side note:

What is saliva actually doing when everything is working the way it should?

Side note:

Because if you think saliva is basically water that keeps the inside of your mouth damp, you're missing most of the story

Side note:

It is mostly water by volume, yes. But mixed into that water

Side note:

are electrolytes, calcium, phosphate, bicarbonate, mucus-like proteins called mucins, digestive enzymes

Side note:

antibodies and several different antimicrobial systems. Whole saliva also picks up cells

Side note:

microorganisms and other material from the mouth as it moves around in

Side note:

there

Side note:

So we're dealing with a lot more than mouth water.

Side note:

Before we buy anything to protect our teeth, moisten our mouth, help digestion, or

Side note:

manage bacteria, our own physiology is already doing a surprising amount of that work

Side note:

That doesn't make toothpaste, dentistry, or medicine unnecessary. It just means there

Side note:

is already a system at work before we add anything to it

Side note:

The body is doing a lot more in the background than we usually give it credit for.

Side note:

Saliva is one small example of that.

Side note:

And when we say saliva comes from salivary glands, we're not talking about one little spit

Side note:

gland somewhere in your cheek. You have three major pairs: the parotid glands up around the

Side note:

cheeks near your ears, the submandibular glands tucked underneath the jaw, and the sublingual glands under

Side note:

the tongue. Then there are hundreds of much smaller salivary glands scattered through the tissues of

Side note:

the mouth

Side note:

They don't all contribute exactly the same kind of secretion, either. Some saliva is more

Side note:

watery; some is more mucus-rich. And the amount changes constantly depending on whether you're

Side note:

resting, chewing, tasting food, sleeping, nervous, or even just thinking about something you're about to

Side note:

eat

Side note:

Even 'my saliva' makes it sound more uniform than it really is. Your nervous system and salivary glands

Side note:

are changing it all day long. And your food doesn't even have to be in your mouth yet

Side note:

Think about biting into a lemon and you can literally make your mouth water. The thought, smell, sight

Side note:

or expectation of food can send nerve signals that turn up salivary secretion. That's part of what's called

Side note:

the cephalic-phase response—your body beginning some of the work of digestion before you've taken the first

Side note:

bite. 'Mouthwatering' is actually pretty literal

Side note:

Also, while we're giving spit a little more respect, humans have found all kinds of uses for it. Spitballs. Spit

Side note:

shining shoes. Sealing envelopes. Wetting thread to get it through a needle. The mom-thumb face wipe, which children everywhere

Side note:

have endured at one time or another. And now we mail tubes of saliva off to laboratories to test our

Side note:

DNA

Side note:

But there is one use of spit I did not see

coming:

Jesus uses spit in three different healing accounts in the

coming:

Gospels

coming:

In Mark 7, Jesus takes a man who is deaf and has difficulty speaking away from the crowd

coming:

He puts His fingers into the man's ears, spits, touches his tongue, looks toward heaven and says, 'Be

coming:

opened

coming:

In Mark 8, Jesus spits on a blind man's eyes and lays His hands on him.

coming:

And in John 9, Jesus does something even stranger. He spits on the ground, makes mud

coming:

with the saliva, puts it on the eyes of a man who has been blind since

coming:

birth, and tells him to wash in the pool of Siloam. The man comes back seeing

coming:

So what was the spit doing there?

coming:

Scripture never says, 'Saliva itself was the medicine.' And clearly Jesus did not need it

coming:

He heals people elsewhere with a word, with a touch, and even from a distance

coming:

But I'm also not convinced the detail is meaningless.

coming:

People in the ancient world really did use saliva medicinally. Pliny the Elder, writing in

coming:

the first century, recorded beliefs about saliva being used for conditions including problems of the

coming:

eyes. Later Jewish writings also describe saliva being applied around the eyes for therapeutic purposes

coming:

So the people watching Jesus would not necessarily have reacted to saliva exactly the way

coming:

we do

coming:

John 9 may be the most fascinating of all.

coming:

Jesus doesn't simply use saliva. He spits into the dirt and makes clay.

coming:

Early Christians noticed something there that I had never really considered: an echo of creation. Genesis

coming:

tells us that God formed man from the dust of the ground. And here is Jesus

coming:

working with earth again as He restores something that had been missing since this man's birth

coming:

John never comes right out and says, 'This is a reference to Genesis,' so I wouldn't turn that into doctrine. But Irenaeus was making

coming:

that connection in the second century. He specifically connected Jesus making clay in John 9 with God forming man from the earth in Genesis

coming:

Three times the Gospel writers deliberately leave spit in the

coming:

story. And every time, Jesus could have healed another way

coming:

Side note, I kept wondering why there is so much mention of using saliva on the eyes…enough to record in

coming:

the Bible and the Shabbat as history. As I dug a little deeper, Eye disease was much more common in the

coming:

ancient world, so remedies for the eyes were part of ordinary life in a way that feels foreign to us now

coming:

Later Jewish writings even mention using early-morning saliva (before you eat) on the eyes because it was believed to be

coming:

especially strong medicinally. We can't say exactly which eye conditions they were treating or that they understood the biology, but it

coming:

does help explain why saliva around the eyes would not have sounded nearly as bizarre then as it does to us

coming:

today

coming:

And there's another interesting angle to saliva. Humans aren't the only creatures whose saliva

coming:

contains compounds involved in protection and repair. Watch a dog or cat get a

coming:

small injury and one of its first instincts is often to lick it. Part

coming:

of that is mechanical cleaning, and saliva itself is biologically active. Research on saliva

coming:

has identified antimicrobial compounds and proteins involved in wound repair, and canine saliva has

coming:

shown antibacterial activity in laboratory research. That doesn't make wound licking automatically helpful - mouths

coming:

also carry microbes, and licking can irritate or contaminate a wound - but the biology

coming:

is still fascinating

coming:

So saliva isn't just waste across mammals. It has real protective biology behind it.

coming:

That makes those Gospel details even more interesting to me. I still wouldn't say Jesus used

coming:

saliva because He needed its medicinal properties—clearly He didn't. But Scripture puts saliva right in

coming:

the middle of these physical healing stories more than once, and I can't help but notice

coming:

that

coming:

It's fascinating. And we never really get a clear answer for why He chose to use it.

coming:

out of ancient history and back into your kitchen. Think about eating something

coming:

really ordinary. A piece of bread. A cracker. A bite of baked potato

coming:

Before that food gets anywhere near your stomach, your brain and salivary glands are already getting involved

coming:

Seeing food, smelling food, tasting it and then chewing all stimulate salivary secretion. Saliva mixes into

coming:

what you're chewing and helps turn it into a soft, cohesive mass that you can actually

coming:

swallow without scraping a dry wad of food down your esophagus. Seeing, smelling, tasting, chewing—even

coming:

thinking about food—can activate brain circuits that eventually converge on salivation centers in the brainstem

coming:

Those centers then send autonomic nerve signals to the salivary glands and tell them to get

coming:

to work

coming:

This is basically the physiology behind Pavlov’s dogs. We remember the

coming:

bell and the drooling, but what Pavlov was really showing was that

coming:

the brain can start preparing the digestive system before food even arrives

coming:

There is a real term for that little chewed-up package: a bolus.

coming:

Which is not a particularly appetizing word, but there you go.

coming:

Saliva also dissolves compounds from food so they can interact with your taste receptors. We tend to think our

coming:

tongue just “tastes” food on contact, but those flavor molecules need a watery environment to reach many of those

coming:

receptors

coming:

So without enough saliva, food can literally taste different.

coming:

Then there is digestion.

coming:

One of the main enzymes in saliva is salivary amylase—AM-uh-lace—which starts breaking down starch

coming:

Your stomach did not receive the opening shift.

coming:

Digestion was already underway while you were chewing.

coming:

I used to picture digestion as food reaching the stomach and then the real work beginning. It starts much earlier than that

coming:

Think about what has already happened before you swallow:

coming:

Your brain anticipates food. Saliva increases. You chew. Food is

coming:

physically broken apart. Saliva moistens it. Taste compounds dissolve. Amylase

coming:

gets access to starch. You form that bolus. You swallow

coming:

The digestive tract is coordinating long before you hear your stomach growl.

coming:

There's also an enzyme that we talk about called lingual lipase. All it is is it

coming:

breaks down fat. Lipase is like lipid, L-I-P. And really, it's just to identify

coming:

that there's different kinds of ingredients in saliva that break down different things in our mouth

coming:

Everything has a responsibility and a purpose that is very intentional. Saliva has a large job

coming:

Then I wondered what that whole process looks like when you don't have enough saliva

coming:

Food is still being chewed, of course, but it’s harder to turn it into

coming:

that soft, cohesive bolus your mouth is trying to make. Dry foods can stick. Swallowing

coming:

can become harder and less comfortable. Taste can change because food molecules aren’t dissolving

coming:

as well. You lose some of that early starch digestion from amylase. And if someone

coming:

already has swallowing problems, less lubrication can make the whole process even more difficult and

coming:

may increase the risk of food going the wrong way. Or aspirate. We think of swallowing

coming:

as something we just do. But saliva is part of what makes that possible without

coming:

us having to think about it

coming:

So saliva isn't just making eating more comfortable. It is helping get

coming:

that bite ready for the next phase before it ever reaches the

coming:

stomach

coming:

Your teeth are not just sitting there waiting for the toothbrush

coming:

This was another part I had seriously underestimated.

coming:

Your teeth spend the entire day in a changing chemical environment.

coming:

Every time you eat certain carbohydrates, bacteria in dental plaque can metabolize them

coming:

and produce acids. That lowers the pH around the tooth making it more

coming:

acidic

coming:

When the environment becomes acidic enough, minerals

coming:

can leave the enamel. That's called demineralization

coming:

And the mineral loss isn't always a one-way trip.

coming:

When conditions improve, minerals can move back into early weakened areas of enamel. Saliva

coming:

contributes calcium and phosphate to that process, while bicarbonate and other buffering systems help

coming:

neutralize acids and bring the oral environment back toward a safer pH. The National

coming:

Institute of Dental and Craniofacial Research notes that early mineral loss can be reversed

coming:

before an actual cavity forms, with minerals from saliva and fluoride helping repair early

coming:

enamel damage

coming:

I knew saliva helped protect teeth. I just didn't realize how much was happening all day long

coming:

Your enamel is constantly sitting in this back-and-forth mineral environment.

coming:

Eat.

coming:

Acid rises.

coming:

Mineral can be lost.

coming:

Saliva dilutes and clears some of those acids, buffering increases, pH

coming:

begins to recover, and calcium and phosphate are available for remineralization

coming:

That doesn't mean saliva grows back a tooth after you've developed a cavity. Once

coming:

enamel has structurally broken down and there's a hole, we're in a different situation

coming:

But before that point, your mouth is constantly working to maintain the mineral environment around your teeth

coming:

How much saliva you're making changes that chemistry too.

coming:

When your salivary glands are stimulated—for example, when you're chewing—saliva generally contains

coming:

more bicarbonate. That gives it greater acid-buffering capacity than very low-flow resting

coming:

saliva. If your mouth remains too acidic, you increase your likelihood for cavities. So

coming:

now I understand why my dad said they didn’t use toothpaste at his

coming:

house…{gasp}. He brushed with baking soda and salt. Salt to mineralize and baking

coming:

soda to neutralize and if I don’t say…..my dad has never had

coming:

a cavity

coming:

So even your saliva isn't chemically identical from one hour to the next.

coming:

I had basically pictured it as a little water fountain in the mouth that helped us swallow

coming:

It is much more responsive than that.

coming:

Once you know what saliva normally does, dry mouth starts to look like more than an annoyance

coming:

When saliva really is low, you start losing some of the protection we've been talking about. Food can become harder to

coming:

chew and swallow. Taste can change. Cavities and oral infections become more likely because acids aren't being cleared and buffered as

coming:

efficiently

coming:

One of the biggest causes today is medication. Antihistamines, some antidepressants, blood-pressure medications, bladder

coming:

medications and quite a few others can reduce saliva. Taking several medications can compound the

coming:

problem

coming:

And dry mouth itself isn't automatically 'just aging.' We see more of

coming:

it with age partly because medications and health conditions become more common

coming:

Dehydration can contribute. Mouth breathing can dry the tissues. Salivary flow drops while we sleep

coming:

Even stress can change it—that cotton-mouth feeling when you're nervous is real autonomic

coming:

physiology

coming:

Then there are conditions like Sjögren's and damage from head-and

coming:

neck radiation where the salivary glands themselves may not be functioning normally

coming:

So if dry mouth sticks around—especially with new cavities, trouble swallowing, or dry eyes

coming:

it's worth bringing up with your dentist or healthcare provider instead of just reaching for

coming:

another

coming:

If the glands still work, chewing is one of the simplest ways

coming:

to stimulate them. That's why gum can help some people with dry

coming:

mouth

coming:

If you're actually dehydrated, correct that. If the dryness started after a medication change, bring that timeline to the

coming:

If the glands are damaged or significantly impaired, though, gum isn't going to fix that. Sometimes

coming:

the better tools are saliva substitutes, extra dental protection, and treating whatever is causing the problem

coming:

This is where spit starts getting even more interesting.

coming:

Saliva contains components involved in immune defense, including

coming:

Those names are a mouthful, so let me translate what they're actually doing.

coming:

Secretory IgA is an antibody found across mucosal surfaces—places like the mouth

coming:

respiratory tract and digestive tract. In saliva, it can bind to microorganisms and

coming:

other antigens and help interfere with their ability to attach and interact with

coming:

tissues

coming:

Lysozyme is an enzyme that can damage the cell walls of certain bacteria.

coming:

Lactoferrin can bind iron. Since microorganisms need iron too, controlling

coming:

its availability is one way the body can influence microbial

coming:

growth

coming:

And salivary peroxidase systems participate in chemical reactions that

coming:

can inhibit certain microbes and help manage potentially damaging

coming:

compounds

coming:

A healthy mouth isn't supposed to be sterile.

coming:

There are large, complex microbial communities living on the tongue, teeth, gums

coming:

and other oral surfaces. Some organisms can contribute to cavities or gum

coming:

disease under certain conditions. Others perform functions that may be useful to

coming:

us

coming:

Saliva helps influence that whole environment. It washes material away, gives some microbes

coming:

places to attach, limits others, and carries immune factors that affect how microbes

coming:

behave

coming:

So 'saliva kills germs' is way too simple.

coming:

The mouth has its own ecosystem, just like

coming:

the gut—and, of course, the two are

coming:

connected

coming:

At this point saliva had already earned more respect than I expected to give it.

coming:

Then I hit the part that really changed the way I thought about the mouth.

coming:

For a long time, a lot of oral-health marketing has basically taught us that bacteria equal bad and stronger killing equals cleaner

coming:

Dental plaque and harmful organisms absolutely matter, and there are times an antiseptic mouthwash

coming:

is useful. But 'stronger killing is always better' turns out to be too simple

coming:

But we now know some oral bacteria are performing

coming:

chemistry that we humans cannot perform efficiently on our

coming:

own

coming:

Because this next piece takes us from spit all the way to blood pressure.

coming:

The beet, the tongue bacteria and the blood vessel

coming:

Let’s say you eat spinach. Or arugula. Or beets.

coming:

Those foods can contain a good amount of nitrate.

coming:

Your digestive tract absorbs that nitrate and it enters your bloodstream.

coming:

So far, nothing strange.

coming:

Then your salivary glands do something I still can't get over.

coming:

They pull some of that nitrate back out of your blood and concentrate it

coming:

into your saliva. Research suggests the glands can take up roughly a quarter of

coming:

the nitrate circulating in the blood and concentrate it many times higher in saliva

coming:

Your body has already absorbed that nitrate—and then it sends some of it back to your mouth

coming:

Why?

coming:

Because certain bacteria living on your tongue can do something with nitrate that our own cells don’t do very efficiently

coming:

They convert nitrate into nitrite.

coming:

Then you swallow that nitrite-containing saliva.

coming:

Now the pathway shifts again.

coming:

Some of that nitrite can be converted into nitric oxide—first in places like the

coming:

acidic stomach and later in blood and tissues, especially under conditions where oxygen is lower

coming:

Nitric oxide is a signaling molecule.

coming:

One of its important jobs is telling the smooth muscle in the walls of blood vessels to relax

coming:

When that muscle relaxes, the vessel widens a little.

coming:

That means blood can move through more easily, which is one

coming:

of the ways nitric oxide helps regulate blood flow and blood

coming:

pressure

coming:

just to be clear, your saliva isn't traveling down to your heart and opening a blood vessel

coming:

Its role happens earlier in the chain.

coming:

Saliva is part of the recycling and processing step that makes the rest possible.

coming:

The salivary glands take nitrate from the blood and put it back into the mouth.

coming:

Your oral bacteria convert it into nitrite.

coming:

You swallow it.

coming:

Then that nitrite becomes available for nitric-oxide production elsewhere in the body

coming:

That whole process is called the enterosalivary nitrate–nitrite–nitric oxide pathway

coming:

The name sounds complicated. The actual idea is much easier.

coming:

Picture it this way:

coming:

You eat a beet.

coming:

The nitrate is absorbed into your blood.

coming:

Your salivary glands pull some of it back out.

coming:

They send it into your mouth.

coming:

Bacteria on your tongue change it into nitrite.

coming:

You swallow it again.

coming:

And farther downstream, that nitrite can help your body make nitric oxide, which

coming:

helps blood vessels relax and supports normal blood flow and blood-pressure regulation

coming:

That recycling is the part I can't get over.

coming:

Your body had already absorbed the nitrate.

coming:

Instead of leaving the nitrate in circulation, the body routes some of it back through the

coming:

mouth because bacteria on the tongue can perform a chemical step we don't do very efficiently

coming:

ourselves

coming:

So the mouth isn't only the entrance to digestion.

coming:

In this pathway, it becomes one stop in a loop that involves the

coming:

gut, blood, salivary glands, tongue bacteria, and then the body again after you

coming:

swallow

coming:

That's why saliva gets some credit here. Spit isn't opening blood vessels, but this salivary

coming:

recycling step helps dietary nitrate move through the pathway that can eventually support nitric-oxide

coming:

production

coming:

If I drew that pathway while trying to invent the human body from scratch, somebody would look at my flowchart and say

coming:

The oral bacteria are doing a real piece of the work here

coming:

converting nitrate to nitrite so the pathway can keep moving after you

coming:

swallow

coming:

That blows my mind. The body had already absorbed the nitrate, then routed some of it back to the mouth because another step could happen there. That feels incredibly intentional to me

coming:

The more I learn about things like this, the harder it is to picture our organs as separate little departments doing their own jobs

coming:

We have the liver, we have the pancreas, we have the kidneys, we have all these organs, but

coming:

then we have all of these other interconnected cycles and processes that are going on all around us

coming:

that there is no way that we could orchestrate any of this all by ourselves. Every piece is

coming:

affecting another. And some of the work is actually being done by organisms that live within us, not

coming:

just the organ

coming:

And somehow spit is right in the middle of it.

coming:

That's a lot going on in something we barely think about.

coming:

And in this case, it can start with a beet. Or spinach. Or arugula.

coming:

Which brings us right back to mouthwash. If tongue bacteria are part of this pathway

coming:

researchers naturally started asking what happens when we repeatedly knock down broad groups of oral

coming:

bacteria

coming:

In studies using strong antiseptic mouthwashes—particularly chlorhexidine—researchers have

coming:

seen nitrate-to-nitrite conversion drop. Some studies have also

coming:

seen small increases in blood pressure while that pathway was

coming:

disrupted

coming:

That does not mean mouthwash causes high blood pressure. The studies are relatively small

coming:

different rinses behave differently, and there are absolutely times when an antimicrobial rinse is

coming:

useful

coming:

But it does make the old idea of 'kill as many mouth bacteria as possible' look a little too simple

coming:

Some of those bacteria are doing jobs we may actually need.

coming:

And that takes me straight back to all those products that promised to make us

coming:

99.9% bacteria-free. Maybe the more useful question is not, 'How much bacteria

coming:

can I kill?' Maybe it's, 'Which bacteria are here, and what are they doing

coming:

I started with spit and expected an episode about moisture. Instead I found a fluid

coming:

that helps us taste dinner, swallow it, start digesting starch, buffer acids, protect enamel, participate

coming:

in immune defense, shape the microbial environment in the mouth and—this still gets me

coming:

help recycle dietary nitrate through tongue bacteria into a pathway involved in blood flow and

coming:

blood-pressure regulation

coming:

Then there was the history. People in the ancient world used saliva medicinally. Later Jewish writings describe early-morning saliva

coming:

being used around the eyes. And the Gospels include spit in three different healing accounts. We still don't know exactly

coming:

why

coming:

Meanwhile, most of us mainly notice it when the dental hygienist asks us to close our lips around the suction tube

coming:

One thing I want Becoming Natural to keep asking is what the body is already doing before we decide we need to add something

coming:

Natural health can turn into a never-ending list of things to buy, take, eat, avoid, or fix

coming:

I don't want to miss the systems that are already working while we're busy looking for the next

coming:

thing

coming:

I already get annoyed remembering my supplements every day. Praise the Lord I don't also have to tell my

coming:

salivary glands when to turn on, remind my enamel to grab minerals, or ask my tongue bacteria to process

coming:

nitrate

coming:

Most of that is happening without me thinking about it at all.

coming:

And saliva gave me a pretty good example of just how much that can include.

coming:

Between toothbrushings, your mouth is already doing a lot of its own maintenance.

coming:

There is so much science there. When I see how much protection, repair, communication, and preparation is

coming:

built into something this ordinary, I have a hard time taking the design of the body for

coming:

granted

coming:

I mean, we're talking about spit—and there is this much coordination built into it.

coming:

That makes me appreciate the body God created a little differently.

coming:

But I do think we can forget how much it is already trying to do for us—and how some of

coming:

our habits, exposures, or treatments can either support those systems or make their job harder. So tonight when you're brushing your

coming:

teeth

coming:

maybe give spit just a tiny bit more respect. If you enjoyed this episode, or you know someone who

coming:

would get a kick out of realizing how much work spit is doing all day, send it their way

coming:

And if this kind of digging into the body, history, and the way God designed us is

coming:

your kind of thing, make sure you're following the show so you don't miss the next one

Links

Video

More from YouTube