The benefits of saliva are easy to miss—until you know how many jobs saliva actually has!
Read the full episode + resources: https://becomingnatural.com/benefits-of-saliva/
In this episode, we look at how saliva helps you taste, chew, swallow, and begin digestion, while also buffering acids, supporting enamel remineralization, and helping regulate the oral microbiome.
We follow the surprising nitrate-to-nitrite pathway that connects bacteria on your tongue with nitric oxide and blood-vessel function. We also look at persistent dry mouth, why medications and mouth breathing matter, and when it deserves more attention.
And we explore the unusual Gospel passages where Jesus used saliva in healing and what people in the ancient world understood about it. By the end, you may never think of spit as “just spit” again.
In This Episode You'll Learn:
• How saliva supports enamel and helps buffer acids in the mouth
• How bacteria on the tongue help convert nitrate to nitrite as part of the nitric-oxide pathway • Why medications, mouth breathing, and other factors can contribute to persistent dry mouth
• Why saliva appears in several Gospel healing accounts and how people in the ancient world understood it
Keep Listening Fluoride Skeptics: Hidden Truth Makes for a Safe and Healthy Life https://becomingnatural.com/fluoride-health-concerns/
This episode is educational and not medical advice. If dry mouth sticks around, or it started after a medication change, bring that to a dentist or the prescriber.
Moms have been using one very questionable cleaning product for generations.
Speaker:No bottle. No spray. Usually applied directly with your hands.
Speaker:And now I have questions. Is it really a cleaner? Does it eradicate 99
Speaker:9% of germs? Or is there actually more biology happening there than we know
Speaker:Is this cleaner Becoming Natural approved?
Speaker:We’re about to find out.
Speaker:Before we get into today’s episode, I wanted to take a few extra minutes and
Speaker:fill you in on what Becoming Natural is becoming—and, with that, where I’ve been
Speaker:If you listen regularly, you’ve probably noticed I’ve missed a few episodes over the summer
Speaker:Becoming Natural is very much alive. In fact, behind the scenes, I
Speaker:ve probably been working on it more than ever. Around the clock
Speaker:actually
Speaker:This summer, I decided to build an entire operating system for the podcast—something that could
Speaker:help me manage research, summaries, the future website, downloads, analytics, SEO, and all the other things
Speaker:I didn’t even know existed when I started. I just knew that I loved researching
Speaker:and writing, but the time it took for the admin tasks was time I could not
Speaker:sustain over time
Speaker:I just want to read and write.
Speaker:Apparently, at this stage of my life, I have also become someone who builds
Speaker:operating systems and talks about code. Which is
Speaker:comical
Side note:I actually took a computer science class in high school. For
Side note:my final project, I built a little matchmaking program in DOS. Ten questions for
Side note:the boys, ten for the girls, compare the answers, and voilà—a match
Side note:My teacher, who was very smart but clearly lacked
Side note:vision for my future empire, made fun of the
Side note:project
Side note:I could have invented Match.com, my friends.
Side note:he apparently thought I was just a silly girl making boys and girls match up on a computer
Side note:Missed opportunity, sir. Sure wish I could tell him now.
Side note:Anyway…
Side note:Building all of this has been fascinating, but the learning curve has been massive. I actually
Side note:I have built things, lost things, recovered things, rebuilt them better, celebrated way too
Side note:late at night because I finally figured something out…and then occasionally woke up
Side note:the next morning to discover that part of my beautiful little puzzle had disappeared
Side note:again
Side note:Some days it has felt like a roller coaster.
Side note:And the perfectionist in me has had a hard time moving forward when I
Side note:know the pieces behind an episode aren’t working the way I want them
Side note:to
Side note:There has been something
Side note:underneath all of that
Side note:though
Side note:When I started this podcast, I thought a lot of my purpose would be
Side note:talking about Crohn’s disease, my healing, and what I learned through that experience
Side note:That was what I knew.
Side note:And I am still incredibly passionate about helping people walking through Crohn’s and chronic illness
Side note:But I’ve realized my story is bigger than Crohn’s.
Side note:The more I study, the more fascinated I become with how our bodies were designed
Side note:how our ancestors used what was available to them to care for their bodies, what
Side note:Scripture teaches us about stewardship, and how connected our physical, emotional, and spiritual health really
Side note:are
Side note:I’ll start researching an episode thinking I’m going to learn about something, and before
Side note:long I’m sitting there with my mouth wide open amazed by what I’m learning
Side note:myself
Side note:The human body is incredible, and apparently this podcast is taking me somewhere I didn't expect to go
Side note:The connection between our bodies and the earth is real—not in some mystical sense, but in
Side note:the very practical reality that the same God who created us also created the world we live
Side note:in
Side note:Our bodies respond to light and darkness. They depend
Side note:on minerals. They interact with plants, food, microbes, seasons
Side note:sleep, movement, stress, and the environment around us every
Side note:single day
Side note:I keep finding myself amazed by those connections.
Side note:I am learning right alongside you.
Side note:Lately I've been thinking a lot about why I'm doing this
Side note:in the first place—and what really belongs under Becoming Natural
Side note:This has become my checkpoint:
Side note:Becoming Natural follows the tension between what we’ve been told, what ancient people observed
Side note:what modern science can actually explain, and what the body has been showing us all
Side note:along
Side note:We look for the surprising connections between physiology, nature, everyday exposures, traditional wisdom, and
Side note:Scripture—the kind of connections that make you stop and say, “I had no
Side note:idea
Side note:Because the closer I look at the body and the world around us, the more intricate the design becomes
Side note:That has become the thread I come back to every episode.
Side note:Does this help us understand the body better?
Side note:Does it make us look more carefully at something we’ve accepted without much thought
Side note:Does it connect what people observed long ago with something science can now help explain
Side note:And does it leave room for me to ask what Scripture has to say without trying to force Scripture into a science lesson
Side note:If it does, it probably belongs here.
Side note:A few years ago, after what I called my “year of no”—a year
Side note:when I desperately needed to simplify my life and find some sanity again—I
Side note:went live on Facebook and announced that I was entering my “year of yes
Side note:Mostly to hold myself accountable. But I remember very clearly sitting in my
Side note:car on a rainy day in the McDonalds parking lot making my declaration
Side note:I said I was going to say yes to doing hard things and accept hard things if I believed that was what God was asking me to do
Side note:The discerning part alone can be hard.
Side note:I also highly recommend being very specific when you make statements like that to the Lord
Side note:My husband and I had done something similar years earlier after hearing a sermon about growing your faith
Side note:We actually prayed for challenges that would grow us.
Side note:I know.
Side note:Bold choice.
Side note:What followed included severe health struggles, sepsis, enormous
Side note:life changes, and eventually my husband leaving his
Side note:job and our family moving to another state
Side note:So…be careful what you pray for.
Side note:But our faith grew.
Side note:Our marriage grew.
Side note:And we learned something through those years that has stayed with us
Side note:even when we had absolutely no idea what was happening, God had
Side note:us
Side note:We had prayed for growth. I don't think either of us pictured it arriving quite like that
Side note:Years later, when this podcast unexpectedly came into my life, I knew saying yes meant sharing more openly about
Side note:my faith, my healing, and some of the things our family had witnessed that I can only describe as
Side note:miracles
Side note:I even talked with my husband about the possibility that doing that might bring some spiritual resistance with it
Side note:Again.
Side note:He was still in.
Side note:He’s always in.
Side note:I just like to run the big God matters past him before I dive in headfirst.
Side note:What I didn't expect was how much growth would come with saying yes to this podcast.
Side note:Since Becoming Natural began, our family has walked through challenge after challenge
Side note:Nothing I need to unpack here today, but enough little things piling up
Side note:that eventually you realize you’re not dealing with one paper cut anymore
Side note:It’s more like a thousand of them, and at some point you start noticing a pattern.
Side note:Growth by strength against resistance. Seems to be my life motto, actually.
Side note:Through all of that, I kept coming back to something I wrote in my journal years ago when
Side note:I was very sick, raising three little boys, and sometimes just trying to make it through the day
Side note:I wrote
Side note:Lord, use me and my words for Your purposes.
Side note:Let my experiences help grow someone’s faith so my pain is not for nothing.
Side note:Let my experience help someone trust You.
Side note:Let me be a vessel.
Side note:Let this be Yours.
Side note:I read that prayer very differently now than I did when I wrote it.
Side note:I have the privilege of hindsight now.
Side note:Back then, I was in the thick of it.
Side note:I was begging for healing while at the same time asking God to use what I was walking through for His purposes
Side note:I don’t think I fully understood what I was asking.
Side note:So yes, that is a big part of where I've been this summer.
Side note:been creating, learning how to build things I never thought I would be
Side note:building, designing the website that has been living in my head, and occasionally
Side note:playing spiritual whack-a-mole—which, truth be told, has not always happened
Side note:without tears
Side note:And I’ve been reading a lot of Scripture.
Side note:Partly because you are trusting me with some pretty big subjects.
Side note:If I’m going to talk about the body, healing, history, natural living, faith, and what Scripture
Side note:says about how we live and care for ourselves, I feel a responsibility to keep learning too
Side note:I don’t want to repeat something just because it sounds good.
Side note:I want to know where it came from and whether it’s true.
Side note:When it comes to science, I want to understand the research well enough to explain it
Side note:When it comes to history, I want to know what actually happened instead of repeating a story that has been passed around the internet a thousand times
Side note:And when I bring Scripture into an episode, I want to be in the Word myself. I
Side note:don’t want to grab a verse because it happens to fit what I already decided I wanted to say
Side note:I've learned some pretty amazing things this summer, and God has not disappointed.
Side note:I’m still here.
Side note:Becoming Natural isn’t slowing down.
Side note:I'm actually trying to build a stronger foundation underneath if the Lord's will is to do so and it grows and does
Side note:something bigger. It can support that growth without me trying to hold everything all by myself with my hands. I just want
Side note:to be faithful with the part that God has put in front of me and let him decide what comes after that
Side note:And after that explanation of where I've been and what I've been doing all summer, today we are going to talk about
Side note:spit
Side note:Are you ready?
Side note:Today we're talking about saliva.
Side note:And I know. Very sophisticated.
Side note:Stay with me, because I kept finding things that made me stop and say, 'Wait—saliva does that too
Side note:I originally started looking into saliva because of dry mouth. That seemed straightforward enough. What causes it? Why
Side note:do some people suddenly develop it? Are medications involved? Does menopause matter? Is it actually because we're dehydrated
Side note:all the time, like every wellness article on earth seems to suggest? is our water actually truly hydrating
Side note:us
Side note:Dry mouth ended up being my way into a much more interesting question:
Side note:What is saliva actually doing when everything is working the way it should?
Side note:Because if you think saliva is basically water that keeps the inside of your mouth damp, you're missing most of the story
Side note:It is mostly water by volume, yes. But mixed into that water
Side note:are electrolytes, calcium, phosphate, bicarbonate, mucus-like proteins called mucins, digestive enzymes
Side note:antibodies and several different antimicrobial systems. Whole saliva also picks up cells
Side note:microorganisms and other material from the mouth as it moves around in
Side note:there
Side note:So we're dealing with a lot more than mouth water.
Side note:Before we buy anything to protect our teeth, moisten our mouth, help digestion, or
Side note:manage bacteria, our own physiology is already doing a surprising amount of that work
Side note:That doesn't make toothpaste, dentistry, or medicine unnecessary. It just means there
Side note:is already a system at work before we add anything to it
Side note:The body is doing a lot more in the background than we usually give it credit for.
Side note:Saliva is one small example of that.
Side note:And when we say saliva comes from salivary glands, we're not talking about one little spit
Side note:gland somewhere in your cheek. You have three major pairs: the parotid glands up around the
Side note:cheeks near your ears, the submandibular glands tucked underneath the jaw, and the sublingual glands under
Side note:the tongue. Then there are hundreds of much smaller salivary glands scattered through the tissues of
Side note:the mouth
Side note:They don't all contribute exactly the same kind of secretion, either. Some saliva is more
Side note:watery; some is more mucus-rich. And the amount changes constantly depending on whether you're
Side note:resting, chewing, tasting food, sleeping, nervous, or even just thinking about something you're about to
Side note:eat
Side note:Even 'my saliva' makes it sound more uniform than it really is. Your nervous system and salivary glands
Side note:are changing it all day long. And your food doesn't even have to be in your mouth yet
Side note:Think about biting into a lemon and you can literally make your mouth water. The thought, smell, sight
Side note:or expectation of food can send nerve signals that turn up salivary secretion. That's part of what's called
Side note:the cephalic-phase response—your body beginning some of the work of digestion before you've taken the first
Side note:bite. 'Mouthwatering' is actually pretty literal
Side note:Also, while we're giving spit a little more respect, humans have found all kinds of uses for it. Spitballs. Spit
Side note:shining shoes. Sealing envelopes. Wetting thread to get it through a needle. The mom-thumb face wipe, which children everywhere
Side note:have endured at one time or another. And now we mail tubes of saliva off to laboratories to test our
Side note:DNA
Side note:But there is one use of spit I did not see
coming:Jesus uses spit in three different healing accounts in the
coming:Gospels
coming:In Mark 7, Jesus takes a man who is deaf and has difficulty speaking away from the crowd
coming:He puts His fingers into the man's ears, spits, touches his tongue, looks toward heaven and says, 'Be
coming:opened
coming:In Mark 8, Jesus spits on a blind man's eyes and lays His hands on him.
coming:And in John 9, Jesus does something even stranger. He spits on the ground, makes mud
coming:with the saliva, puts it on the eyes of a man who has been blind since
coming:birth, and tells him to wash in the pool of Siloam. The man comes back seeing
coming:So what was the spit doing there?
coming:Scripture never says, 'Saliva itself was the medicine.' And clearly Jesus did not need it
coming:He heals people elsewhere with a word, with a touch, and even from a distance
coming:But I'm also not convinced the detail is meaningless.
coming:People in the ancient world really did use saliva medicinally. Pliny the Elder, writing in
coming:the first century, recorded beliefs about saliva being used for conditions including problems of the
coming:eyes. Later Jewish writings also describe saliva being applied around the eyes for therapeutic purposes
coming:So the people watching Jesus would not necessarily have reacted to saliva exactly the way
coming:we do
coming:John 9 may be the most fascinating of all.
coming:Jesus doesn't simply use saliva. He spits into the dirt and makes clay.
coming:Early Christians noticed something there that I had never really considered: an echo of creation. Genesis
coming:tells us that God formed man from the dust of the ground. And here is Jesus
coming:working with earth again as He restores something that had been missing since this man's birth
coming:John never comes right out and says, 'This is a reference to Genesis,' so I wouldn't turn that into doctrine. But Irenaeus was making
coming:that connection in the second century. He specifically connected Jesus making clay in John 9 with God forming man from the earth in Genesis
coming:Three times the Gospel writers deliberately leave spit in the
coming:story. And every time, Jesus could have healed another way
coming:Side note, I kept wondering why there is so much mention of using saliva on the eyes…enough to record in
coming:the Bible and the Shabbat as history. As I dug a little deeper, Eye disease was much more common in the
coming:ancient world, so remedies for the eyes were part of ordinary life in a way that feels foreign to us now
coming:Later Jewish writings even mention using early-morning saliva (before you eat) on the eyes because it was believed to be
coming:especially strong medicinally. We can't say exactly which eye conditions they were treating or that they understood the biology, but it
coming:does help explain why saliva around the eyes would not have sounded nearly as bizarre then as it does to us
coming:today
coming:And there's another interesting angle to saliva. Humans aren't the only creatures whose saliva
coming:contains compounds involved in protection and repair. Watch a dog or cat get a
coming:small injury and one of its first instincts is often to lick it. Part
coming:of that is mechanical cleaning, and saliva itself is biologically active. Research on saliva
coming:has identified antimicrobial compounds and proteins involved in wound repair, and canine saliva has
coming:shown antibacterial activity in laboratory research. That doesn't make wound licking automatically helpful - mouths
coming:also carry microbes, and licking can irritate or contaminate a wound - but the biology
coming:is still fascinating
coming:So saliva isn't just waste across mammals. It has real protective biology behind it.
coming:That makes those Gospel details even more interesting to me. I still wouldn't say Jesus used
coming:saliva because He needed its medicinal properties—clearly He didn't. But Scripture puts saliva right in
coming:the middle of these physical healing stories more than once, and I can't help but notice
coming:that
coming:It's fascinating. And we never really get a clear answer for why He chose to use it.
coming:out of ancient history and back into your kitchen. Think about eating something
coming:really ordinary. A piece of bread. A cracker. A bite of baked potato
coming:Before that food gets anywhere near your stomach, your brain and salivary glands are already getting involved
coming:Seeing food, smelling food, tasting it and then chewing all stimulate salivary secretion. Saliva mixes into
coming:what you're chewing and helps turn it into a soft, cohesive mass that you can actually
coming:swallow without scraping a dry wad of food down your esophagus. Seeing, smelling, tasting, chewing—even
coming:thinking about food—can activate brain circuits that eventually converge on salivation centers in the brainstem
coming:Those centers then send autonomic nerve signals to the salivary glands and tell them to get
coming:to work
coming:This is basically the physiology behind Pavlov’s dogs. We remember the
coming:bell and the drooling, but what Pavlov was really showing was that
coming:the brain can start preparing the digestive system before food even arrives
coming:There is a real term for that little chewed-up package: a bolus.
coming:Which is not a particularly appetizing word, but there you go.
coming:Saliva also dissolves compounds from food so they can interact with your taste receptors. We tend to think our
coming:tongue just “tastes” food on contact, but those flavor molecules need a watery environment to reach many of those
coming:receptors
coming:So without enough saliva, food can literally taste different.
coming:Then there is digestion.
coming:One of the main enzymes in saliva is salivary amylase—AM-uh-lace—which starts breaking down starch
coming:Your stomach did not receive the opening shift.
coming:Digestion was already underway while you were chewing.
coming:I used to picture digestion as food reaching the stomach and then the real work beginning. It starts much earlier than that
coming:Think about what has already happened before you swallow:
coming:Your brain anticipates food. Saliva increases. You chew. Food is
coming:physically broken apart. Saliva moistens it. Taste compounds dissolve. Amylase
coming:gets access to starch. You form that bolus. You swallow
coming:The digestive tract is coordinating long before you hear your stomach growl.
coming:There's also an enzyme that we talk about called lingual lipase. All it is is it
coming:breaks down fat. Lipase is like lipid, L-I-P. And really, it's just to identify
coming:that there's different kinds of ingredients in saliva that break down different things in our mouth
coming:Everything has a responsibility and a purpose that is very intentional. Saliva has a large job
coming:Then I wondered what that whole process looks like when you don't have enough saliva
coming:Food is still being chewed, of course, but it’s harder to turn it into
coming:that soft, cohesive bolus your mouth is trying to make. Dry foods can stick. Swallowing
coming:can become harder and less comfortable. Taste can change because food molecules aren’t dissolving
coming:as well. You lose some of that early starch digestion from amylase. And if someone
coming:already has swallowing problems, less lubrication can make the whole process even more difficult and
coming:may increase the risk of food going the wrong way. Or aspirate. We think of swallowing
coming:as something we just do. But saliva is part of what makes that possible without
coming:us having to think about it
coming:So saliva isn't just making eating more comfortable. It is helping get
coming:that bite ready for the next phase before it ever reaches the
coming:stomach
coming:Your teeth are not just sitting there waiting for the toothbrush
coming:This was another part I had seriously underestimated.
coming:Your teeth spend the entire day in a changing chemical environment.
coming:Every time you eat certain carbohydrates, bacteria in dental plaque can metabolize them
coming:and produce acids. That lowers the pH around the tooth making it more
coming:acidic
coming:When the environment becomes acidic enough, minerals
coming:can leave the enamel. That's called demineralization
coming:And the mineral loss isn't always a one-way trip.
coming:When conditions improve, minerals can move back into early weakened areas of enamel. Saliva
coming:contributes calcium and phosphate to that process, while bicarbonate and other buffering systems help
coming:neutralize acids and bring the oral environment back toward a safer pH. The National
coming:Institute of Dental and Craniofacial Research notes that early mineral loss can be reversed
coming:before an actual cavity forms, with minerals from saliva and fluoride helping repair early
coming:enamel damage
coming:I knew saliva helped protect teeth. I just didn't realize how much was happening all day long
coming:Your enamel is constantly sitting in this back-and-forth mineral environment.
coming:Eat.
coming:Acid rises.
coming:Mineral can be lost.
coming:Saliva dilutes and clears some of those acids, buffering increases, pH
coming:begins to recover, and calcium and phosphate are available for remineralization
coming:That doesn't mean saliva grows back a tooth after you've developed a cavity. Once
coming:enamel has structurally broken down and there's a hole, we're in a different situation
coming:But before that point, your mouth is constantly working to maintain the mineral environment around your teeth
coming:How much saliva you're making changes that chemistry too.
coming:When your salivary glands are stimulated—for example, when you're chewing—saliva generally contains
coming:more bicarbonate. That gives it greater acid-buffering capacity than very low-flow resting
coming:saliva. If your mouth remains too acidic, you increase your likelihood for cavities. So
coming:now I understand why my dad said they didn’t use toothpaste at his
coming:house…{gasp}. He brushed with baking soda and salt. Salt to mineralize and baking
coming:soda to neutralize and if I don’t say…..my dad has never had
coming:a cavity
coming:So even your saliva isn't chemically identical from one hour to the next.
coming:I had basically pictured it as a little water fountain in the mouth that helped us swallow
coming:It is much more responsive than that.
coming:Once you know what saliva normally does, dry mouth starts to look like more than an annoyance
coming:When saliva really is low, you start losing some of the protection we've been talking about. Food can become harder to
coming:chew and swallow. Taste can change. Cavities and oral infections become more likely because acids aren't being cleared and buffered as
coming:efficiently
coming:One of the biggest causes today is medication. Antihistamines, some antidepressants, blood-pressure medications, bladder
coming:medications and quite a few others can reduce saliva. Taking several medications can compound the
coming:problem
coming:And dry mouth itself isn't automatically 'just aging.' We see more of
coming:it with age partly because medications and health conditions become more common
coming:Dehydration can contribute. Mouth breathing can dry the tissues. Salivary flow drops while we sleep
coming:Even stress can change it—that cotton-mouth feeling when you're nervous is real autonomic
coming:physiology
coming:Then there are conditions like Sjögren's and damage from head-and
coming:neck radiation where the salivary glands themselves may not be functioning normally
coming:So if dry mouth sticks around—especially with new cavities, trouble swallowing, or dry eyes
coming:it's worth bringing up with your dentist or healthcare provider instead of just reaching for
coming:another
coming:If the glands still work, chewing is one of the simplest ways
coming:to stimulate them. That's why gum can help some people with dry
coming:mouth
coming:If you're actually dehydrated, correct that. If the dryness started after a medication change, bring that timeline to the
coming:If the glands are damaged or significantly impaired, though, gum isn't going to fix that. Sometimes
coming:the better tools are saliva substitutes, extra dental protection, and treating whatever is causing the problem
coming:This is where spit starts getting even more interesting.
coming:Saliva contains components involved in immune defense, including
coming:Those names are a mouthful, so let me translate what they're actually doing.
coming:Secretory IgA is an antibody found across mucosal surfaces—places like the mouth
coming:respiratory tract and digestive tract. In saliva, it can bind to microorganisms and
coming:other antigens and help interfere with their ability to attach and interact with
coming:tissues
coming:Lysozyme is an enzyme that can damage the cell walls of certain bacteria.
coming:Lactoferrin can bind iron. Since microorganisms need iron too, controlling
coming:its availability is one way the body can influence microbial
coming:growth
coming:And salivary peroxidase systems participate in chemical reactions that
coming:can inhibit certain microbes and help manage potentially damaging
coming:compounds
coming:A healthy mouth isn't supposed to be sterile.
coming:There are large, complex microbial communities living on the tongue, teeth, gums
coming:and other oral surfaces. Some organisms can contribute to cavities or gum
coming:disease under certain conditions. Others perform functions that may be useful to
coming:us
coming:Saliva helps influence that whole environment. It washes material away, gives some microbes
coming:places to attach, limits others, and carries immune factors that affect how microbes
coming:behave
coming:So 'saliva kills germs' is way too simple.
coming:The mouth has its own ecosystem, just like
coming:the gut—and, of course, the two are
coming:connected
coming:At this point saliva had already earned more respect than I expected to give it.
coming:Then I hit the part that really changed the way I thought about the mouth.
coming:For a long time, a lot of oral-health marketing has basically taught us that bacteria equal bad and stronger killing equals cleaner
coming:Dental plaque and harmful organisms absolutely matter, and there are times an antiseptic mouthwash
coming:is useful. But 'stronger killing is always better' turns out to be too simple
coming:But we now know some oral bacteria are performing
coming:chemistry that we humans cannot perform efficiently on our
coming:own
coming:Because this next piece takes us from spit all the way to blood pressure.
coming:The beet, the tongue bacteria and the blood vessel
coming:Let’s say you eat spinach. Or arugula. Or beets.
coming:Those foods can contain a good amount of nitrate.
coming:Your digestive tract absorbs that nitrate and it enters your bloodstream.
coming:So far, nothing strange.
coming:Then your salivary glands do something I still can't get over.
coming:They pull some of that nitrate back out of your blood and concentrate it
coming:into your saliva. Research suggests the glands can take up roughly a quarter of
coming:the nitrate circulating in the blood and concentrate it many times higher in saliva
coming:Your body has already absorbed that nitrate—and then it sends some of it back to your mouth
coming:Why?
coming:Because certain bacteria living on your tongue can do something with nitrate that our own cells don’t do very efficiently
coming:They convert nitrate into nitrite.
coming:Then you swallow that nitrite-containing saliva.
coming:Now the pathway shifts again.
coming:Some of that nitrite can be converted into nitric oxide—first in places like the
coming:acidic stomach and later in blood and tissues, especially under conditions where oxygen is lower
coming:Nitric oxide is a signaling molecule.
coming:One of its important jobs is telling the smooth muscle in the walls of blood vessels to relax
coming:When that muscle relaxes, the vessel widens a little.
coming:That means blood can move through more easily, which is one
coming:of the ways nitric oxide helps regulate blood flow and blood
coming:pressure
coming:just to be clear, your saliva isn't traveling down to your heart and opening a blood vessel
coming:Its role happens earlier in the chain.
coming:Saliva is part of the recycling and processing step that makes the rest possible.
coming:The salivary glands take nitrate from the blood and put it back into the mouth.
coming:Your oral bacteria convert it into nitrite.
coming:You swallow it.
coming:Then that nitrite becomes available for nitric-oxide production elsewhere in the body
coming:That whole process is called the enterosalivary nitrate–nitrite–nitric oxide pathway
coming:The name sounds complicated. The actual idea is much easier.
coming:Picture it this way:
coming:You eat a beet.
coming:The nitrate is absorbed into your blood.
coming:Your salivary glands pull some of it back out.
coming:They send it into your mouth.
coming:Bacteria on your tongue change it into nitrite.
coming:You swallow it again.
coming:And farther downstream, that nitrite can help your body make nitric oxide, which
coming:helps blood vessels relax and supports normal blood flow and blood-pressure regulation
coming:That recycling is the part I can't get over.
coming:Your body had already absorbed the nitrate.
coming:Instead of leaving the nitrate in circulation, the body routes some of it back through the
coming:mouth because bacteria on the tongue can perform a chemical step we don't do very efficiently
coming:ourselves
coming:So the mouth isn't only the entrance to digestion.
coming:In this pathway, it becomes one stop in a loop that involves the
coming:gut, blood, salivary glands, tongue bacteria, and then the body again after you
coming:swallow
coming:That's why saliva gets some credit here. Spit isn't opening blood vessels, but this salivary
coming:recycling step helps dietary nitrate move through the pathway that can eventually support nitric-oxide
coming:production
coming:If I drew that pathway while trying to invent the human body from scratch, somebody would look at my flowchart and say
coming:The oral bacteria are doing a real piece of the work here
coming:converting nitrate to nitrite so the pathway can keep moving after you
coming:swallow
coming:That blows my mind. The body had already absorbed the nitrate, then routed some of it back to the mouth because another step could happen there. That feels incredibly intentional to me
coming:The more I learn about things like this, the harder it is to picture our organs as separate little departments doing their own jobs
coming:We have the liver, we have the pancreas, we have the kidneys, we have all these organs, but
coming:then we have all of these other interconnected cycles and processes that are going on all around us
coming:that there is no way that we could orchestrate any of this all by ourselves. Every piece is
coming:affecting another. And some of the work is actually being done by organisms that live within us, not
coming:just the organ
coming:And somehow spit is right in the middle of it.
coming:That's a lot going on in something we barely think about.
coming:And in this case, it can start with a beet. Or spinach. Or arugula.
coming:Which brings us right back to mouthwash. If tongue bacteria are part of this pathway
coming:researchers naturally started asking what happens when we repeatedly knock down broad groups of oral
coming:bacteria
coming:In studies using strong antiseptic mouthwashes—particularly chlorhexidine—researchers have
coming:seen nitrate-to-nitrite conversion drop. Some studies have also
coming:seen small increases in blood pressure while that pathway was
coming:disrupted
coming:That does not mean mouthwash causes high blood pressure. The studies are relatively small
coming:different rinses behave differently, and there are absolutely times when an antimicrobial rinse is
coming:useful
coming:But it does make the old idea of 'kill as many mouth bacteria as possible' look a little too simple
coming:Some of those bacteria are doing jobs we may actually need.
coming:And that takes me straight back to all those products that promised to make us
coming:99.9% bacteria-free. Maybe the more useful question is not, 'How much bacteria
coming:can I kill?' Maybe it's, 'Which bacteria are here, and what are they doing
coming:I started with spit and expected an episode about moisture. Instead I found a fluid
coming:that helps us taste dinner, swallow it, start digesting starch, buffer acids, protect enamel, participate
coming:in immune defense, shape the microbial environment in the mouth and—this still gets me
coming:help recycle dietary nitrate through tongue bacteria into a pathway involved in blood flow and
coming:blood-pressure regulation
coming:Then there was the history. People in the ancient world used saliva medicinally. Later Jewish writings describe early-morning saliva
coming:being used around the eyes. And the Gospels include spit in three different healing accounts. We still don't know exactly
coming:why
coming:Meanwhile, most of us mainly notice it when the dental hygienist asks us to close our lips around the suction tube
coming:One thing I want Becoming Natural to keep asking is what the body is already doing before we decide we need to add something
coming:Natural health can turn into a never-ending list of things to buy, take, eat, avoid, or fix
coming:I don't want to miss the systems that are already working while we're busy looking for the next
coming:thing
coming:I already get annoyed remembering my supplements every day. Praise the Lord I don't also have to tell my
coming:salivary glands when to turn on, remind my enamel to grab minerals, or ask my tongue bacteria to process
coming:nitrate
coming:Most of that is happening without me thinking about it at all.
coming:And saliva gave me a pretty good example of just how much that can include.
coming:Between toothbrushings, your mouth is already doing a lot of its own maintenance.
coming:There is so much science there. When I see how much protection, repair, communication, and preparation is
coming:built into something this ordinary, I have a hard time taking the design of the body for
coming:granted
coming:I mean, we're talking about spit—and there is this much coordination built into it.
coming:That makes me appreciate the body God created a little differently.
coming:But I do think we can forget how much it is already trying to do for us—and how some of
coming:our habits, exposures, or treatments can either support those systems or make their job harder. So tonight when you're brushing your
coming:teeth
coming:maybe give spit just a tiny bit more respect. If you enjoyed this episode, or you know someone who
coming:would get a kick out of realizing how much work spit is doing all day, send it their way
coming:And if this kind of digging into the body, history, and the way God designed us is
coming:your kind of thing, make sure you're following the show so you don't miss the next one