•An article titled "Aldo-Keto Reductase 1C1 (AKR1C1) as the First Mutated Gene in a Family with Nonsyndromic Primary Lipedema" published in the International Journal of Molecular Sciences in August 2020, by a group of researchers in Italy. •This study analyzed the genetic profile of three women with lipedema in one family. •They believe they have come up with the first genetic basis for lipedema. •When we can identify genes that are linked to lipedema, this can be used for diagnostic purposes. •This may lead to earlier diagnosis, earlier intervention with better outcomes, and possible prevention of progression to later stages of lipedema.

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