In today’s episode, we’ll talk about a paper that discusses a potential pathway for chronic low-grade inflammation to occur in lipedema, which contributes to resistance to fat loss and promotes further adipose tissue expansion.

The paper is titled, “Is the endotoxin–complement cascade the major driver in lipedema?” by Dr. Kruglikov from Germany and Dr. Scherer from the USA.

It was published in the peer-reviewed journal Trends in Endocrinology & Metabolism in September 2024.

This paper is important for individuals with lipedema because it offers another possible option for intervention and management of troubling symptoms of lipedema.