Histamine intolerance spikes in the four to seven days before your period, because progesterone and estrogen drop together and you lose DAO support and GABA buffering at the same time.
Liz & Becca break down why perimenopause makes it worse, whether ox bile and digestive enzymes are safe with a gallbladder, and why a normal hs-CRP doesn't rule out inflammation. Hives, migraines, insomnia, bloating, constipation, anovulatory cycles and mast cells — the hormone drop is the trigger, not the cause.
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