In Episode 10 of Younger By the Minute, Jamie and Jennifer Speiser unpack the biggest takeaways from the A4M Longevity Conference and explain why Precision Medicine is no longer the future, it’s the standard.

This episode dives deep into how gut health, inflammation, hormones, peptides, GLP medications, CGMs, and metabolic health are all interconnected. Rather than chasing symptoms, Jamie and Jennifer explain why long-term health, performance, and longevity depend on identifying and fixing root causes first.

They explore why hormonal imbalance is rarely the primary issue, how gut dysbiosis fuels inflammation and disease, the proper way to use GLPs and peptides, and why data-driven tools like continuous glucose monitors (CGMs) are essential for personalized care. This conversation is a masterclass in understanding how the body functions as a system and how small daily choices compound into long-term health outcomes.

If you’re interested in longevity, hormone optimization, metabolic health, or truly individualized medicine, this episode will change how you think about health and aging.

⏱️ Episode Chapters

00:00 – Welcome & Why This Conference Was Different

01:17 – Precision Medicine Becomes Mainstream

02:08 – Why Gut Health Comes Before Hormones

03:09 – Gut Health, Serotonin & Mental Wellness

04:19 – Inflammation, Detoxification & Hormone Clearance

05:06 – Precision Testing & Personalized Treatment Plans

06:17 – Gut Microbiome, Stress & Chronic Disease

07:17 – Vagus Nerve Dysfunction & Digestive Shutdown

08:58 – Estrogen Recycling, Constipation & Hormone Risk

09:47 – GLPs, Protein Digestion & Inflammation

10:18 – Why PPIs Make Gut Health Worse

11:28 – Hormones as a Downstream Issue

12:01 – Treating Symptoms While Fixing Root Causes

13:17 – Peptides as Messengers (and Why Environment Matters)

15:30 – Inflammation as the Driver of Aging

16:24 – Precision vs Symptom-Based Medicine

17:13 – Health Tech, Wearables & Data Without Emotion

18:41 – Taking Autonomy Over Your Health

19:23 – Biological Age vs Chronological Age

20:13 – GLPs, CGMs & Using Data to Prevent Damage

21:30 – Protein Intake, Muscle Loss & Ozempic Face

23:08 – How to Calculate Protein the Right Way

25:42 – Micronutrient Deficiencies & Chronic Disease

27:45 – The Future of Precision Medicine at Precision Life

29:38 – Why Everything Starts With Precision Medicine

30:16 – The Evolution of Healthcare & Final Thoughts

🔑 Key Takeaways

1. Hormonal imbalance is rarely the root cause. Gut health, inflammation, and detoxification come first
2. Chronic inflammation accelerates aging, disease, and metabolic dysfunction
3. GLP medications and peptides require a healthy internal environment to work properly
4. Protein deficiency leads to muscle loss, metabolic damage, and accelerated aging
5. PPIs and appetite suppressants often worsen long-term gut health
6. CGMs provide objective data that removes emotion and guesswork from health decisions
7. Precision medicine adapts as the patient evolves. It’s not a one-size-fits-all approach
8. Longevity is about slowing damage, not chasing youth
9. True health optimization requires treating the entire system, not isolated symptoms

Sponsors / Mentions

Precision Life • Precision Fitness • Precision Aesthetics • Precision Medicine • Trueline Media Group

If this helped, like, subscribe, and share with a friend who’s ready to design their next chapter.

About Precision Life:

We integrate training, nutrition, functional medicine, and regenerative aesthetics for results that look natural and last.

Our goal is to help you live your best life.

Find out more about Precision Life at https://precisionlife.io/

Follow us at :

Jamie:

Facebook: https://www.facebook.com/jamie.speiser.5

Instagram: https://www.instagram.com/thejamiespeiser/

Jennifer:

Facebook: https://www.facebook.com/jennifer.hollow.9

Instagram: https://www.instagram.com/thejenniferspeiser/

Precision:

Facebook: https://www.facebook.com/precisionlifestl

Instagram: https://www.instagram.com/precisionlifestl/

Trueline Media Group

https://www.truelinemediagroup.com/

Hey. Hello and welcome to

another episode of Younger by the Minute.

2

One of your host, Jamie Speiser.

3

And I'm always here with my other host.

4

Jennifer Speiser.

5

and we have a lot of exciting things

to talk about.

6

Yeah, we just came off the A4M

Longevity Conference in Las Vegas.

7

And, you know, it was a really good

conference first and foremost.

8

I love going to these things.

9

You said you get to learn you protocols.

10

You get to see all the new devices and

techniques and stuff that's coming out.

11

And I think for us, this weekend

wasn't just about trends.

12

I think it was more about confirmation

that medicine is finally shifting towards

13

finding, finding and fixing the root

14

cause versus just addressing the symptoms.

15

It's about us, about resilience

and just about long term vitality.

16

Yeah, I mean, our philosophy for over

a decade has been starting with

17

really nutrition and fitness

and then expanding

18

into athletics and growing into,

I should say, more than a decade.

19

But growing into the full

precision medicine.

20

And what's crazy is when we

when you created

21

precision, you had no idea that

this is where we would end up.

22

And this is also where medicine would end

up. Yeah.

23

Yeah. It's 2011.

24

Oh, yeah.

25

Precision medicine,

though, is actually now a term.

26

And it's something

that we've been focusing on.

27

And, you know, really

they've really dove into

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gut health

and how muscle equals on gravity.

29

And those are the things

30

that we've been saying all along,

which it was really cool because it's

31

it was very validating.

32

But then we also took

some really key pieces away

33

that are going to help us yield

even better, better patient outcomes.

34

Yeah, we always walk away some really good

nuggets, you know, on there.

35

And like you said, it's

a lot of the stuff.

36

It's it's really good to see the emphasis

and how they are talking about

37

the importance of gut microbiome,

its importance of it adrenals and the fact

38

of how much stress really correlates

into everything, and that these things

39

need to be looked at and addressed before

really even getting into sex hormones.

40

And it's something

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I know I've been talking heavily

on, on our social, on my social media page

42

for a good three plus years, and it's been

43

ever since we've created,

44

like incorporated precision

medicine into our practice.

45

It's been the root of it is addressing

the gut, addressing the adrenals,

46

going after the thyroid, optimizing

those things re checking it

47

and getting new, levels on blood work

and then going after sex hormones.

48

Yeah, because if the gut's off

or the person is systemically inflamed,

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mostly probably because the gut is off,

50

they're not going to become

metabolically optimized.

51

Like you've got to almost like clean out.

52

Now you're the mechanic here.

53

So I'm going to probably butcher this,

but it's like you got to do it.

54

Engine cleaning or an oil like what

would you do before you put fresh oil in.

55

You got to like clean it out, right?

56

They popped the drain

plug and ran the oil off.

57

But if you have dirty oil, it's

really hard to get the engine to crack.

58

Yeah, right. Yeah.

59

There's other things

you need to do to get all the

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the grime out of the lifters and,

and and all that stuff.

61

But you know, it's even like, even when

you, you know, we talk about gut health.

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Right. And we know that, that

the gut is the second brain.

63

We know that it produces

a lot of serotonin.

64

So then when you look

at the advertising of testosterone,

65

one of the symptoms of low

T is depression.

66

Well so is poor gut health.

67

You know depression

because you're not you're not producing

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this serotonin and that you would

if your gut was optimized.

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So you know you're fixing a symptom

with one thing.

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When it could be completely

something different.

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Well yeah.

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And also you know

you have your four organs of excretion.

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So if the gut's off which is an organ of

excretion, the liver's off and the liver,

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the liver being dirty,

for lack of a better word or term,

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if that's off, you're not going to be able

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to break down things

that you put in your body correctly.

77

And so then you're really going to end up

just doing yourself a disservice.

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You can actually create

an influx of those hormones.

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Or if the patient has MTHFR

and they can't genetically breakdown

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certain medications,

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they can start to have

a surge of those hormones

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and then they're going to have less

than desirable outcomes.

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And so I think that's really what,

you know, it was really cool.

84

Like and

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where it seems like the medical world

is really the path that they're paving.

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And why it feels different is because

that focus on precise medical treatment.

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So you're looking at the individual

and you are getting to the root cause,

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and then you're having all these

to look at all of these

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different puzzle pieces to then

put that specific puzzle back together.

90

Your pieces are different than my pieces.

91

And so on and so forth.

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So being able

to do some specialized testing,

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which is what we're going to now offer,

or even be able to utilize

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things that can truly have real time

data on someone's

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blood glucose when we're utilizing certain

peptides, it's really important

96

because we're making a very precise plan

for their specific puzzle.

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Right.

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You know,

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even when they get into inflammation,

you know, again, we've talked heavily

100

on inflammation and what is causing

inflammation within the body.

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Dietary choices.

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Alcohol,

not optimizing your sleep, stress.

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Unresolved stress

like you're not managing your stress.

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Like I said, alcohol.

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But there's several factors

that go into that.

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But the thing you have to remember is that

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that's all change in the gut microbiome.

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And also the gut microbiome is a cause.

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It's not just a consequence disease

and not just a genetic, hormonal or

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immune disease is not often the downstream

result of microbiome imbalance.

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But think of it

in terms of prebiotic forces,

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which support life

diversity and regulation.

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It's also like an antibiotic force

which kills, suppresses, and fragments,

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sorry, ecosystems.

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So every choice of food that you eat

has an impact.

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Every time that you eat changes

the gut microbiome.

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Every, every time with that stress, sleep,

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timing and medication

to all have impact on this.

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Yeah.

120

And if you try to just go ahead

and fix it on your own,

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sometimes the microbiome already has such

its own network of its own personality,

122

like you have you as a being,

but then you also have

123

this other living entity inside of you,

which is your gut microbiome.

124

And so then if you're overloaded

with Candida or Sibo or CFO

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and you keep feeding that bad

bacteria, it's really impossible.

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And they have a conscience, as do

parasites.

127

Parasites have their own conscience.

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So, you know, it's interesting,

but we're not alone in our own bodies.

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And we have to remember that.

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And unfortunately, the stripped soil

and the lack of nutrient dense food

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and all these other things

are absolutely killing our gut microbiome.

132

And then it's causing a cascade effect.

133

You know,

you have uncontrolled inflammation,

134

you have endocrine disruption,

135

you have a variety of other things

that then also feed mental

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wellness and mental vigor.

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And just in the decline, like we're going

to have a rebound effect of what's

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going to happen later if people don't

really understand what they're doing now.

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Right now.

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I sat out on one of the lectures, too,

and the one they really tapped into again,

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which is something we've talked

about, is the vagus nerve.

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And that's

kind of like the missing therapy,

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which you are seeing a lot of stuff

come out on now

144

you're seeing more and more, more

and more on social media.

145

You're seeing more and more ads,

seeing more.

146

It's just being

talked about more in general.

147

But you know, you got

148

to understand that it's the most powerful

microbiome intervention.

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It is going to cause chronic stress.

150

It turns off digestion.

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It reduces microbiome diversity,

and it promotes inflammation.

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Well, just think about it.

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So now we're all pretty much

we all have some sort

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of vagal tone dysregulation.

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As someone that has had severe

consequences

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to having their vagus nerve go haywire,

I understand that.

157

I mean, the gut dysbiosis is insane

to the point of constipation, for days.

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And so what happens is the vagus

159

nerve is also partly responsible

for gut peristalsis.

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And when we shallow breathe

and we're not getting enough breath

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and we're not oxygenating,

but also expanding our diaphragms,

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it starts to dis

regulate that vagus nerve.

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So the now combine that with someone

who's finally had enough,

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and now they're on too high

of a dose of a GLP one.

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What's their food doing?

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It's literally

sitting inside of them and rotting.

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It's not you know, it's becoming

these issues and they're becoming toxic.

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And so a lot of people

169

don't realize that when we're constipated,

you're recycling bad estrogen.

170

So while the whole topic of HRT

being bad for so long

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and how detrimental it was

to the female population in medicine

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because they completely halted

all research on women's health

173

due to these black

box warnings that were false?

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We now have recycled estrogen.

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It's just a mess

and it becomes a situation where unopposed

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estrogen can really be detrimental

to breast tissue, ovarian tissue

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and things like that.

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And unfortunately,

that estrogen is not even the estrogen

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that's going to keep your heart

or your brain safe.

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Right?

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You know, I'm

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you brought up a good point about

just food just sitting the digestion,

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because as humans,

we're not designed to ferment protein

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and fat and bone,

protein should be digested.

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That should be absorbed,

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and it should be metabolized

before ever reaching the colon.

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Undigested protein in the colon equals

inflammation.

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Some people will feel better

on a carnivore diet at first,

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but then over time

they start to feel worse,

190

especially if they're on a GLP two

or GLP three,

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which sometimes in some cases,

they'll be better on a GLP one.

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Like semaglutide,

Ozympic when it's when it first phase.

193

But the important thing with that

is, again, we come back to the gut

194

and having a healthy gut all starts

with having the proper amount of,

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stomach acid in the stomach to break down

and digest the food so it doesn't

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sit there and ferment

and turn into Sibo cf0,

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which then turns into what everybody knows

mainstream or doctors

198

diagnosed with as reflux, Gerd, leaky gut,

or IBS.

199

Well, and the thing is, is

200

the biggest thing that people want to do

when they start to have acid

201

reflux is turn to a PPI

or proton pump inhibitor.

202

And what that actually is doing

is making a bigger situation,

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because now you're suppressing

even more of the abilities.

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the body's ability to produce stomach acid

so becomes this vicious cycle.

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And the thing is, is I think this is what

why A4M felt different

206

this year was because they had lectures

on how bad PPIs can be.

207

They had lectures on how to do things

a safe way, and if we aren't

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educating other physicians this way,

then who's going to help patients?

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And then how do we get there?

210

Because we are in a country where we have

we're we're kind of run by big pharma

211

in general and not, you know, people

they the health care

212

system makes more money off sick

people than healthy people at this time.

213

Right.

214

And there one one other lecture too,

that I, you know, I just really wish

215

I could have been live on social media

and I would just love around and say it.

216

But, you know, they were talking

about hormones and the microbiome

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and hormonal imbalance is rarely primary.

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You know, it's rarely the primary cause.

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It's it's estrogen, Thyroid,

cortisol issues often stemmed from micro

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microbiome imbalance

impaired detoxification and inflammation.

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Examples of that

when it comes back to painful,

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heavy periods

PCOS, Hashimoto's and endometriosis

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by by improving the microbiome, diversity

often reduces

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these menstrual pains, improves

ovulation, and lowers autoimmune markers.

225

So again, coming back to

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you can't

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really properly prescribe sex hormones

if you haven't fixed the other things

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first that are down regulating the number

on the blood panel that you're

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now prescribing the HRT with.

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Or at least or at the very least,

which is what we do if you are

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that symptomatic

that you are having insomnia

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or vaginal dryness, and it's affecting

your marriage and all of these things,

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you can treat the symptoms

while you treat the root cause.

234

You can do it in at the same time,

but you have to do both.

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And then you have to watch the doses

that you started that patient with,

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because they end up not needing

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that high of a dose

once everything else does fall into place.

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And as someone who has been dysregulated,

I do believe that it probably

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all happened with my gut first,

and then it got worse

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because I was prescribed

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birth control pills, and then I completely

went into adrenal fatigue.

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I mean, that's the point

that I'm trying to say, though

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some people do have a good microbiome

and they need something else fixed, right?

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But at the same time, it's

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what is the root cause

and how are we getting to the root cause?

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And how does your assessment address

the root cause?

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You know, some people,

because they're so adapted to their gut

248

dysbiosis, they don't even realize

that they are having gut issues.

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I can't tell you

how many patients are like,

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no, I don't get bloating,

distention or anything.

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And then as I dig in a little bit more,

they're like, oh, well,

252

actually that food bothers me or that food

bothers me, you know, they don't.

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They're just so used to it, right? 100%.

254

And I think that even you know what you're

talking about, what that even correlates

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into, something that's really trending

right now is just peptides in general.

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You know, peptides are not

they're new to social media.

257

There are new to the public, but

they're not new to is being is how long

258

you've been around because some of them

been around for over 50 plus years.

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But also, you know, you got to remember

peptides are messengers.

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But in order for them to work,

then it needs to be in the

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in the right environment, like the,

the gut.

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And everything needs to be prepared

in order for the messaging

263

to be clear, you know, think of like

like a bad telephone game, right?

264

You know, you keep going to eventually

gets the original message, gets lost.

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Well, if your body's completely inflamed,

if the gut by is off and this

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then the peptide as a messenger

can't really there's.

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Nowhere to go. Right.

268

You know, it's it's it's bouncing.

269

It's like what fires bigger?

Where do I need to go?

270

Bouncing off several versus

what it's supposed to be

271

as a direct pathway

to the problem it’s just getting

272

bad Intel along the way.

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The good news is, is though, because they

they do treat systemically

274

and very safely, like with a very low side

effect or adverse event profile.

275

In some cases, there's zero adverse

event profiles like with BPC 157,

276

which like you said,

277

I mean, it's been around

since the Cold War,

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which actually is made up

of gastric juices and

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and these peptides that come from I mean,

peptides are small chains of amino acids

280

that come from protein that are actually

naturally occurring in the body.

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So the body recognizes them very well.

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And so unlike medications that you take,

you're not trading one thing for another.

283

You're not like if you listen

to all the fast

284

talkers at the end of the commercials,

it's like, here,

285

this might help you

with your erectile dysfunction,

286

but you could drop dead of a heart attack

at the same time.

287

Like you're not training,

you're not trading one thing for another

288

that could actually be

289

significantly worse than what it is

that you're trying to treat.

290

So it's nice because they do go in there.

291

But what is cool

about what you're talking about is yes,

292

it might not know where to go.

293

The patient is still going to feel better

because they

294

if it is the gut, it's going to bring down

systemic inflammation, which therefore

295

will help increase

feeding time of healing time

296

and then also help with pains

or whatever that they might have.

297

Because again, back to what

we've been talking about.

298

Systemic inflammation

is honestly the root cause.

299

And it's inflammation

is also what causes aging.

300

So when you look at the disease

process of aging. Resistance.

301

It's all these things.

302

Well then insulin resistance

also accelerates aging.

303

It's like everything it's it's

just you end up creating

304

a whole systemic trash can fire

that you can't get out.

305

And you are right.

306

It's like they will still work, right.

307

But for the cost,

you're going to spend on that.

308

You know, it's

not going to be a quick fix.

309

It's not the end all be all,

but the maximize ROI.

310

Make sure that when you're using them

or going to start using them,

311

that you put yourself and your body

312

in a good environment to properly absorb

and utilize them to the max

313

100%.

314

You know, and I

think that's the thing, like, I think what

315

really providers

need to really pay attention to

316

and what patients need to look for

when they're looking at providers is,

317

are you treating my symptoms or are you

trying to look more at the systems?

318

And you know what?

319

You can't just treat them

and it's not just

320

the precision

medicine, preventative medicine,

321

whatever you want to call it,

functional medicine.

322

It's not just this woowoo thing,

it's it's a real thing

323

that needs to be talked about.

324

Because if you go back to the grass roots

of, you know, making sure

325

that you're eating super foods,

making sure

326

that you're getting plenty of sleep,

making sure that you're hydrating,

327

if you do all those things,

you're going to be far more ahead

328

than other people around you,

or even what you could be yourself.

329

I mean, you're going to create issues

if you don't eat right or sleep well.

330

Correct.

331

And I think another big part of the

the conference too, was the trade show.

332

You know, the amount of technology

that's out now, I.

333

Know I wanted everything.

334

Yeah.

335

So, you know, pan fed,

336

but hydro, not hydrogen but oxygen.

337

H Bots.

338

H Bots and.

339

Red lights.

340

Right? Is it was all awesome.

341

You know, you just got to remember, you

know, even, like, with the stellar program

342

that I've created,

you know, the precision technology,

343

it gives you insight, it gives you data,

and the data has no emotion.

344

It's kind of like

when you run a business and stuff,

345

like when you look at numbers,

numbers are factual.

346

There's no emotion behind it.

347

The issue comes with some technology

like what was it, the Wolf

348

and Apple Watch and stuff like that.

349

Just like the scale.

350

People get obsessed, you know, with it,

and they truly don't understand the data

351

that's coming back out of it.

352

So make sure that when you're using

these things that the data

353

that you're that you're getting

and the information

354

that you're getting out of it,

they're you're making decisions.

355

The right decisions.

356

But most importantly, like,

don't get anxious about it.

357

You know, it's yeah,

358

easier said than done, you know.

359

Well, but you're right.

360

Go ahead. You're right.

361

Because if you're stressing about that,

you're still stressing your body out.

362

Right?

363

So it's like, you know, I mean, sometimes

I have to tell myself that, like,

364

okay, like if you really want to, like,

you're creating your own stress here

365

and that's the thing

I want people to understand.

366

Take the power back.

367

You have the power to have full autonomy.

368

And you know,

when you go to the doctor's office,

369

you have the power to to ask the questions

and to not allow

370

the paternal relationship that happens

with some patient provider relationships.

371

They’re are a doctor, and yes,

they went to medical school,

372

but medicine is forever evolving,

and if they're not open minded enough,

373

they've lost track of what they signed up

for from the beginning.

374

Because this is the evolution of medicine

it's been since day one.

375

We did, you know, when we made penicillin,

you know that. Yeah.

376

It's all these different discoveries

and that's what makes it fun.

377

And there are so many things out there.

378

And, you know, I said earlier

that aging is a disease process.

379

And you were talking about measurables.

380

One of the really cool things to do

is to test your biological age.

381

You know,

you can be chronologically in age,

382

but that doesn't mean

that your body is that age.

383

Whether it's good or bad.

384

It could be older or not as old.

385

Right? So, you know, there's are

they are these things.

386

And so that is just the number.

387

And longevity comes from slowing down

the damage, not just chasing youth.

388

And that even comes

from mitochondrial dysfunction.

389

And really understanding that metabolic

dysfunction is one of those drivers,

390

along with inflammation

being the accelerator of degeneration,

391

because that's what's going to break down

telomeres.

392

That's what you're going to shorten them.

393

So then your lifespan

is going to be shorter.

394

That's what's going to cause you

to be fatigued at a cellular level,

395

which is going to then cause you

to have thyroid issues and other issues,

396

which then you start to drink more energy

drinks and take things to wake up,

397

and it becomes this vicious cycle

that you have to get out of.

398

Right.

399

And then, you know, another big topic out

there was about GLPs

400

and where they're at.

401

And it is awesome to hear so many of these

402

people speaking highly about them.

403

But again, they always came back

to properly using them properly

404

being educated on getting the right

blood work and stuff like that,

405

and utilizing a CGM, which is one of the

things that we've done.

406

Because what I realize, you know,

that the GLP's are not going anywhere.

407

People are.

408

They're here, people want them,

they're going to use them.

409

So the best thing we can do

is educate them.

410

And instead of going at it and arguing,

411

I shouldn't say arguing,

but trying to do it's it comes across.

412

This is my opinion of this

and my opinion of that.

413

The CGM gives you

factual gives us factual data.

414

So if someone is on a GLP

and they don't want to listen thinking

415

that, well, I can still eat 1

or 2 meals a day and I'm fine with that,

416

that Stello is going to come out

and show them that

417

how low they're actually running, and then

we can correlate to them like you are.

418

The data is showing you

you're running too low for too long

419

and you're creating damage because now

we can see it in your blood work too

420

can can you explain really quickly

also so people understand

421

because you brought it up earlier,

422

protein is supposed to be absorbed

and digested right away,

423

and your entire body is made up of like

water and protein and yes, some fat.

424

But like you need protein.

425

It's the building block of everything.

426

A lot of times

when people are not getting or anytime

427

someone's not getting adequate nutrition,

whether they're out training it,

428

whether they're starving themselves,

whether they're

429

whatever they become,

what's known as catabolic.

430

And that's why people are getting

ozempic face and ozempic butt

431

because they're actually their body

is smarter than they are, or all of us

432

is, it's your body will always do

whatever it needs to do to survive.

433

So instead of burning fat,

you start to burn muscle.

434

Correct. And like I said before,

435

there's no

436

difference between someone

being on 90mg of Adderall

437

as someone on phentermine or on the

the billion dollar industry of fat burners

438

where their

everything is an appetite suppressant,

439

where people are eating one number, 1

or 2 meals a day,

440

they're not hitting

their protein requirement,

441

but they're still weightlifting

30 minutes to an hour.

442

They're still doing 30 minutes

to an hour of cardio.

443

The outcome is going to be the same

whether they're on the GLP

444

or on the Adderall, they're on

the phentermine they're, on a fat burner

445

or they have an eating disorder,

the outcome is going to be the same.

446

And, Doctor Gabrielle

Lyons Lyons brought up something.

447

I've the way I've been doing nutrition

for the longest time is

448

whenever I look at someone's

caloric intake needs,

449

you know, it's a it's

a multiplier times their weight.

450

And that's where you.

I'll get the caloric intake need.

451

But I never look at protein

as a percentage

452

because what's what they teach you in

dietary.

453

It's, you know, point

eight kilograms per pound of weight.

454

Well that by by that standard

that's the minimum.

455

That's the thing

that people didn’t realize

456

that's the that's a minimum number.

457

Kind of like when you drink

half your body weight in ounces of water

458

that well, that's

the minimum requirement of water.

459

That doesn't mean

you shouldn't be drinking more.

460

That's just a good basis to figure out

what's the minimum amount

461

you need to function for the day,

462

the way I've always done it, and it's

exactly the way that she described it.

463

It's it's one gram to 1.25g per

464

lean body mass, not weight,

but per lean body mass.

465

That is your number.

466

Then you can take that number times four.

467

So like if you figure out that your lean.

468

So like say I'm 138. Sorry.

469

But then I'm really like 124.

470

Let's say yeah

471

you're 138 and weight then cause lean body

mass is probably see around 110.

472

We'll just do it two times the one.

473

That's 110.

474

Take that times four.

475

Well, that's 440 calories.

476

Now I can subtract that out

477

calorie diet or a 2200,

whatever the number is.

478

Now I can do a percentage based on fat,

based on carbs, based on body

479

type, based on activity, based on insulin

resistance or insulin sensitivity.

480

Our hormones, thyroid, what is all that?

481

Is that optimizer your unoptimized,

you know, am I building them up

482

from one meal a day

to four meals a day or three meals a day?

483

You know what?

484

That plays a factor on how I figure out

the rest of that caloric intake.

485

But for protein, I've always never done it

486

as a percentage of 15 to 25% of the diet.

487

I've always done it at a gram, 1.25g

488

per lean body weight,

and then I adjust the the fat

489

and the carbs based on the energy

expenditure on the individual.

490

Well that's the thing I think that people

aren't getting like they,

491

they're only looking at calories,

492

they're not looking at

what's going to sustain them.

493

And so then they're just not still not

eating right for whatever their plan is,

494

whether they're on a GLP or not.

495

And that's what we

496

so I've said before like, you know,

if you're just going to count calories,

497

well, you could hit your caloric intake

with two slices of pizza in a day,

498

but that ain't going to get you towards

a goal.

499

No. Yeah, I ain't going to lean you out.

500

That isn't going to build muscle.

501

But you but you hit your caloric intake.

502

You know, making up

your macronutrients is important.

503

But like we've said in previous episodes,

really

504

honing in and making

sure your micronutrients are getting hit

505

along with your macronutrients

and are being adjusted

506

based on how you lean out

and how your activity is.

507

And then based on your labs and how they

improve or wherever they're setting that.

508

Well, the other thing.

509

So micronutrients are lacking in

almost every person's diet

510

at this point due

to the quality of food in this country.

511

And those micronutrient deficiency over

time is

512

what's leading to hypertension

to a whole bunch of other things,

513

because we need those minerals

and the things that come from that,

514

and we're inadequate in them.

515

So that's where the slow like the slow,

slow, slow

516

increase of disease processes comes from.

517

And, you know, and that's the other thing

I want to make it known like Precision

518

Medicine, part of the definition is,

is that it adapts as the patient evolves.

519

So you start, you know, you might

start here even with your meal plans.

520

They change.

521

And so everything's customizable

and everything is starting

522

with the root cause.

523

And then it's

going to become more foundational.

524

And that's the thing that I really want

listeners to know.

525

Like when we do labs, for example,

I'm excited for January's labs

526

that I'm going to do, I'm

527

actually going to pull serum, salivary

and urine and put my panels up

528

and do a video of them so people can see,

because you have to utilize

529

different measurables and different ways

to really get a true understanding.

530

Like with glucose, you know, it's

there's a short window of time which.

531

So when you get a glucose on a serum

blood panel, it's very variable.

532

So insulin is much more reliable

than glucose.

533

But when you're wearing a continuous

534

glucose monitor, you get that snapshot

of how you're moving through the day.

535

So you got to hone in on your yeah, hone

in on what foods are spiking.

536

You have stress is spiking you.

537

Or when you get too low.

538

But you know they have to.

539

Or like if you ate a really fatty meal

and then got your lipids down,

540

your, your triglycerides.

541

So you've got to take into consideration

the variables when you get those labs.

542

And for females, a lot of people

don't know that you really need

543

to go on day between 19 and 22

to get an accurate progesterone level.

544

Unless you're on contraceptive

or your postmenopausal.

545

So it's just, you know,

you're just going off of these ranges.

546

And then a lot of times

they're not looking at the symptoms

547

and they're just like, oh, well, you're

ranges are normal and you're fine, right?

548

I think that's some of the new stuff

that's coming.

549

You know,

550

we're bringing back a lot to precision,

which is

551

why I love going to these conferences

because, you know,

552

there are things we learn,

there are things that are validated

553

that we've been doing that validate,

we've been going the right direction.

554

We've been teaching our clients

the right way.

555

And, you know,

556

we're going to be doing a deeper dive

into some genetic testing and integration.

557

We're going to be comparing

those genetics with blood work, gut

558

testing, the CGM testing,

obviously looking at clinical response.

559

But we're very excited going into 2026

560

and all the new things that we can bring

and offer our clients and better us

561

as providers

and give a better service to our clients

562

and really be a platform to help people

advocate for themselves and be a resource

563

for them to to learn something,

maybe to do it a different way.

564

Absolutely.

565

Because even for like the precision

medicine is actually now the root of

566

like the tree trunk

or the roots of our entire practice.

567

Because if you're

568

if you're a

569

physiology is in alignment

and you're, you know, everything's working

570

the way it should,

571

then your esthetic outcomes are going to

be even better because you have the things

572

that you need to support, you know,

whether it's from cellular nutrition.

573

So when you do procedures

like regenerative injectables

574

or microneedling or anything

that you're doing to try to provoke

575

new cells

to form and grow by the wound response,

576

you have to have cells

577

that have proper nutrition or they're not

going to do their job effectively.

578

Or if you're

579

somebody that is too catabolic and you're

trying to put filler in somebody,

580

or if they are postmenopausal

and you're trying to stimulate collagen,

581

you're just going to keep

hitting your head against the wall

582

just on the other side of that,

the fitness if you're too catabolic,

583

if you are postmenopausal,

if you're not hormonally aligned,

584

then your results are going to take longer

or just not get there.

585

So in order

for everything to be in alignment

586

and for you to get the best results

and to have the the life that you want

587

for as long as you want, you have to start

with precision medicine 100%.

588

Now, let's say as we wrap up

today's episode,

589

you know, I would

I know you're in the same boat.

590

I just want to say how grateful we are

for spaces like A4M, AMMG

591

spaces that bring together

people who are like minded

592

asking better questions about health

593

and how they can do better

within their practice.

594

I will say like when we sort of go on this

like five, six years ago,

595

like 2 or 300 people

I know in that one lecture

596

we where in probably

597

That’s wild.

598

So it was really great to see that people.

599

From other countries,

600

like I met a doctor from Mexico

and it was just it was cool to see.

601

Yeah, it's

602

it's really growing some legs and it's

really and I'm really happy to see that.

603

And I will say,

we've been building precision

604

with this philosophy

for well over a decade.

605

Starting started with fitness

when it was just me

606

and then and we fitness and nutrition,

I should say.

607

And then we expand that.

608

When we opened up in 2014

into the aesthetics.

609

And then we've grown in this

610

into a full precision medicine,

as you put it, on that part of it.

611

But as we call it, it, call it now

and everything, it's precision life

612

because we really are trying to coach

and teach

613

people a long term lifestyle

that's doable.

614

That is not just a cyclical diet

or a cyclical thing that you do

615

just because you got some bad news,

or just because you have some form of an

616

event coming up.

617

Well, no.

618

And that's why our logo is the way it is.

619

It's all connected,

every piece is connected

620

and it's all encompassing,

621

and it's because it is, you know,

we're working on mind, body, spirit.

622

We're working on the physiology

from the inside out

623

and really trying to help

people live their best life.

624

Right.

625

All right.

626

Well, that wraps up another episode.

627

We appreciate you tuning in. As always.

628

I'm Jamie Speiser, I'm out.

629

I'm Jennifer Speiser, and thank you. Hey.