Low ferritin is rarely a simple iron shortage. Liz & Becca break down the five anemia patterns they see on an iron panel — true deficiency, a conversion problem, anemia of chronic disease, B12/folate anemia, and iron overload — and why only one of them is fixed by taking iron.
Covers the functional ranges they use, hepcidin and iron sequestration, why low ferritin drives heavier periods, when in your cycle to test, and the mitochondrial reason you can be exhausted with a perfectly normal CBC.
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There's so many people struggling with this, and your doctors
Liz Roman:are just gonna tell you that it's normal.
Becca Chilcz:Just take iron.
Liz Roman:Yeah, that too.
Liz Roman:Just take iron.
Liz Roman:We're gonna watch it.
Becca Chilcz:And at the end of the day, guys, we have to understand
Becca Chilcz:that unfortunately, the doctors don't have the tools or the capacity
Becca Chilcz:to dive deeply into this for you.
Liz Roman:And it's like, okay, did anybody look at how they're doing with
Liz Roman:their cycles and the heavy bleeding?
Becca Chilcz:Because if you are be- like, even if you're below a 50 of
Becca Chilcz:ferritin, you're not feeling great.
Becca Chilcz:We're not in a place where we're gonna be growing hair well, and
Becca Chilcz:hair, you know, skin and nails are gonna be healthy, and energy and
Becca Chilcz:recovery and all of those things.
Liz Roman:And there's five different patterns that we're gonna go through today
Liz Roman:and help you understand what your body and the pattern is trying to tell you.
Liz Roman:So women will have this miss for decades.
Becca Chilcz:And so you kind of have to fight for yourself and
Becca Chilcz:find your own answers sometimes.
Liz Roman:Hello, and welcome back to the Health Revival Show.
Liz Roman:We're talking all things iron anemia and low ferritin, because
Liz Roman:y'all don't seem to get it yet.
Liz Roman:Mm-mm.
Liz Roman:No.
Liz Roman:There's so many people struggling with this, and your doctors are just
Liz Roman:gonna tell you that it's normal.
Liz Roman:Your ferritin is above a 15, and it's not flagging low on your blood work, or even
Liz Roman:sometimes it is flagging low, and they're like, "Oh, we'll just keep an eye on it.
Liz Roman:We'll just watch it."
Becca Chilcz:Like- Just take iron
Liz Roman:Yeah, that too.
Liz Roman:Just take iron, we're gonna watch it, come back and let us know in three months.
Liz Roman:And it's like, okay, did anybody look at how they're doing with
Liz Roman:their cycles and the heavy bleeding?
Liz Roman:Because low iron, low ferritin can result in heavier menstrual periods and bleeds
Liz Roman:and clotting and all kinds of things.
Liz Roman:Uh, so that's what we're gonna get into today, and we're gonna talk about
Liz Roman:the different patterns, because you would see this as one problem, and
Liz Roman:there's five different patterns that we're gonna go through today and help
Liz Roman:you understand what your body and the pattern is trying to tell you.
Liz Roman:If your body is looking for iron, if it's sequestering iron because
Liz Roman:there's an infection and it's trying to protect you, it will lock it up.
Liz Roman:Or if you have a true anemia here and you really need to consider potentially
Liz Roman:an infusion, oral iron, a patch, sublingual, lactoferrin, all the types
Liz Roman:of things, and then we'll also talk about hemochromatosis, uh, at the end
Liz Roman:here and what o- iron overload is.
Liz Roman:And I don't know if you've experienced this, Becca, but I have
Liz Roman:gotten several people who's like, "Well, what about this pattern?
Liz Roman:What about this pattern?" It's like, these are the main five, and you need to
Liz Roman:look at the ranges, and so we're gonna walk you through all of that today.
Liz Roman:If you wanna grab a pen and paper.
Liz Roman:If you're watching us on YouTube, you can follow along.
Liz Roman:Also, we have a great guide that you can download for free and be able to
Liz Roman:go through this and understand your pattern, and then we'll also share with
Liz Roman:you some of the things that we do and implement and things that you may want
Liz Roman:to watch out for and things that we don't recommend doing, which is a lot of
Liz Roman:what your doctor's gonna tell you to do.
Becca Chilcz:Yeah, and a- at the end of the day, guys, we have to understand
Becca Chilcz:that unfortunately, the doctors don't have the tools or the capacity to dive
Becca Chilcz:deeply into this for you, and so that is why it is a Your options are take iron,
Becca Chilcz:come back later, or an iron infusion, which neither actually solve the
Becca Chilcz:problem of what's going on at the root.
Becca Chilcz:So that's what we wanna talk about today is where, where these patterns
Becca Chilcz:essentially originate from, what they look like on your blood work,
Becca Chilcz:tighter blood work ranges so that you know what you should be looking for
Becca Chilcz:versus what your LabCorp thing says.
Becca Chilcz:Because if you are be- like, even if you're below a 50 of
Becca Chilcz:ferritin, you're not feeling great.
Becca Chilcz:We're not in a place where we're gonna be growing hair well, and
Becca Chilcz:hair, you know, skin and nails are gonna be healthy, and energy and
Becca Chilcz:recovery and all of those things.
Becca Chilcz:And yes, timing of when you test this does matter because obviously if you just had
Becca Chilcz:a period, you're gonna have lower iron.
Becca Chilcz:Like, don't time it around that.
Becca Chilcz:Time it leading into your cycle, which is also about when you usually wanna
Becca Chilcz:get hormones tested if you're testing hormones in a preme- uh, premenopausal
Becca Chilcz:female and they're having a normal cycle and consistent cycle, you usually wanna
Becca Chilcz:test around day 19 to 22 or so if you have that, like, 26 to 28-day cycle.
Becca Chilcz:So timing of when you test matters, and then trends matter, too.
Becca Chilcz:I would say that I see iron flip pretty frequently, and so if we see
Becca Chilcz:something kinda low, I'm looking for other patterns to go along with it.
Becca Chilcz:Ferritin's a little bit more of a storage shedding, right?
Becca Chilcz:And then we're looking at hemoglobin, we're looking at hematocrit, and these
Becca Chilcz:other markers that give us clues into, like, true deficiencies that have
Becca Chilcz:reached other parts of the system, right?
Becca Chilcz:So let's first talk about what's measuring what, um, and, you know, explain the
Becca Chilcz:markers that we're looking at here.
Becca Chilcz:So Typically, we run four markers with an iron panel, and then we
Becca Chilcz:also run an additional marker that gives us insight into inflammation,
Becca Chilcz:a, a general insight, right?
Becca Chilcz:So serum iron is first.
Becca Chilcz:That's obviously, like, what's in your bloodstream right now
Becca Chilcz:of iron, your tank, you know?
Becca Chilcz:Ferritin is what's in storage.
Becca Chilcz:What has your body been able to kind of put away into storage?
Becca Chilcz:And a big reminder here is that if your body is under chronic
Becca Chilcz:stress, if you are under chronic inflammation, it doesn't have the
Becca Chilcz:capacity to put anything in storage.
Becca Chilcz:Like, you're burning through things.
Becca Chilcz:It's just keeping it what it can into circulation.
Becca Chilcz:So it's a huge clue for a lot of people, if you have chronically low ferritin,
Becca Chilcz:a lot of times it's a cellular problem.
Becca Chilcz:It's a problem of what is going on that's not allowing you to even put
Becca Chilcz:anything in storage because it's so needed in actual circulation right now.
Becca Chilcz:So we'll get into that, obviously.
Becca Chilcz:Total iron binding capacity is how hard your body is hunting for iron.
Becca Chilcz:Percent saturation is how much of the ride is actually occupied, so, like,
Becca Chilcz:how much of the little cars taking iron around are actually consumed with iron.
Becca Chilcz:And then CRP.
Becca Chilcz:We run CRP, HS-CRP, a little bit different, but same general idea, whether
Becca Chilcz:inflammation is kind of faking the numbers, because CRP measures IL-6, which
Becca Chilcz:is produced by the liver, and so the liver tends to be very heavily involved
Becca Chilcz:in iron, in sequestri- sequestering of iron, in production and release of iron.
Becca Chilcz:So we'll get into all of that.
Becca Chilcz:But those are the big numbers that we're looking at.
Becca Chilcz:That's what we're gonna give kind of ideas around, um, in terms of, you
Becca Chilcz:know, ranges and what we wanna see.
Becca Chilcz:So now you understand what we're looking for.
Liz Roman:Yeah.
Liz Roman:So if you have your labs and you wanna get them out right now, I'm gonna take
Liz Roman:you through what our optimal ranges are.
Liz Roman:And again, this is very different than what you're gonna see on
Liz Roman:a LabCorp or a Quest panel.
Liz Roman:So as Becca mentioned, your ferritin, which is your storage tank, if we are
Liz Roman:very low, we're gonna feel exhausted.
Liz Roman:We're gonna be depleted.
Liz Roman:We're gonna have hair loss and low energy, brain fog.
Liz Roman:All kinds of things can be associated with low ferritin.
Liz Roman:But also on the flip side, if it's really high, it can be
Liz Roman:an indicator of inflammation.
Liz Roman:So the functional range, and now I will say that functional
Liz Roman:ranges definitely vary.
Liz Roman:There are different schools of thoughts on this.
Liz Roman:I have been trained that over 100 is a sign of inflammation.
Liz Roman:I've also been trained that it can go up to 150 if we're looking at
Liz Roman:the broader picture to say, "Okay, no, things are actually okay."
Liz Roman:I would say both of us would agree that a sweet spot for ferritin is in the ballpark
Liz Roman:of 80 to 120, even though a functional range that has been provided through
Liz Roman:various blood chemistry courses says 50 to 100 When we look at hair specifically,
Liz Roman:I wanna see at least an 80, and this is also for cycling females because we
Liz Roman:don't wanna have those heavy periods.
Liz Roman:And when ferritin gets low, iron gets low, that is going to cause heavier bleeding,
Liz Roman:and we obviously don't wanna do that.
Liz Roman:And heavier bleeding over long periods of time is going to
Liz Roman:deplete your iron stores as well.
Liz Roman:So 50 to 100, we would say really the sweet spot is 80 to 120.
Liz Roman:Beck, I don't know if you have anything different there to share, but I don't
Liz Roman:like that top end being so high, and I also think 100's a bit too low.
Liz Roman:You have to look at, at the pattern and the trend and everything else, right?
Liz Roman:'Cause we'll also look at your hemoglobin, hematocrit, right,
Liz Roman:on your complete blood count.
Liz Roman:There's some markers that can be indicative of anemia there.
Liz Roman:Serum iron, this is your total iron that you're looking on your labs, 85 to 130.
Liz Roman:If we're looking at transferrin, this is not one that we
Liz Roman:always run, but 200 to 350.
Liz Roman:This is the iron delivery driver.
Liz Roman:Um, and so if your iron is high, this is your body kind of
Liz Roman:scrambling to move more iron.
Liz Roman:So think of that as your delivering driver.
Liz Roman:Transferrin saturation, so this is how full those delivery driver trucks are.
Liz Roman:If it's low, there's not enough iron being delivered, and this is
Liz Roman:a key deficiency marker as well.
Liz Roman:Then we have total iron binding capacity.
Liz Roman:So this is total seats on the bus, if you will, for iron.
Liz Roman:Lots of empty seats can point to a deficiency, so we would wanna see
Liz Roman:that somewhere between 250 and 400.
Liz Roman:And then we have UIBC as well, and this is unfilled seats, and if it's high, there's
Liz Roman:room to spare, so there's a deficiency.
Liz Roman:So it's kind of flip-flopped here.
Liz Roman:And low would be inflammation and overload.
Liz Roman:So you might see some of those other markers that we didn't mention, 'cause
Liz Roman:typically on our panel it's gonna be total iron, ferritin, binding
Liz Roman:capacity, and percent saturation.
Liz Roman:All right.
Liz Roman:So when we look at five anemia patterns that women show, I think this is really
Liz Roman:important to understand, and we're gonna specifically for the first couple
Liz Roman:highlight the binding capacity because again, as Becca mentioned before,
Liz Roman:this is going to be telling us how hard your body is hunting for iron.
Liz Roman:So if we have, let's go in the empty tank here, low iron, low ferritin,
Liz Roman:high binding capacity, and low percent saturation, this is your body asking for
Liz Roman:iron High total iron binding capacity is the tell that your body needs it.
Liz Roman:This is a true, you know, deficiency.
Liz Roman:The body is building more, uh, drivers because there's nothing left to haul
Liz Roman:essentially, so we need to find the leak.
Liz Roman:Is this heavy cycles?
Liz Roman:Is it malabsorption, so low stomach acid, need for vitamin C?
Liz Roman:All of those things in your gut microbiome are gonna be imperative to
Liz Roman:you absorbing the iron from your foods, but also thinking about things that would
Liz Roman:block iron absorption from those foods.
Becca Chilcz:Yeah,
Liz Roman:absolutely.
Liz Roman:This can be … I also wanna say here, sometimes you don't wanna ignore this
Liz Roman:if this is ongoing and there's a lot of GI issues, because it could be an
Liz Roman:internal bleed in the GI tract or, like, an ulcer or something along those lines.
Liz Roman:So again, this is just a caveat.
Liz Roman:Like, these are patterns, but you may have further investigation to do.
Liz Roman:When we look at a low or normal binding capacity, this is gonna tell us that
Liz Roman:your body is not absorbing this.
Liz Roman:So we wanna think here in terms of, you know, thyroid.
Liz Roman:Iron builds thyroid hormone, and low thyroid means heavier periods
Liz Roman:and worse absorption as well.
Liz Roman:So this is gonna be a pattern of normal iron, low ferritin, normal binding
Liz Roman:capacity, and normal percent saturation.
Liz Roman:So the only thing in this pattern is that your ferritin is low, so we
Liz Roman:need to focus on your conversion.
Liz Roman:What helps conversion?
Liz Roman:Lactoferrin, vitamin C, stomach acid.
Liz Roman:And then we could argue things like folate and B12 and all the different
Liz Roman:B vitamins, but this is really where iron is moving fine, but you're just
Liz Roman:not converting it and storing it.
Liz Roman:So for me, when I see this pattern, I'm gonna go and I'm gonna look at other
Liz Roman:patterns and trends on blood work to say how many markers indicate a gut infection
Liz Roman:or inflammation or malabsorption, right?
Liz Roman:Does she show other deficiency patterns in terms of a need for
Liz Roman:magnesium, a need for vitamin D, right?
Liz Roman:There's a lot of things that we can see, and we talk about this in our,
Liz Roman:uh, webinar series that we did, Labs Decoded, and that's in our FitMom Society.
Liz Roman:So if you want to understand, this is one panel that we look at amongst many.
Liz Roman:If you wanna understand that, you can go to fitmomsociety.com.
Liz Roman:There's a seven-day free trial.
Liz Roman:Access that.
Liz Roman:It's an hour, uh, five hours essentially, but it's split up into,
Liz Roman:uh, one-hour segments that you can go through the different panels, and
Liz Roman:you can understand all those other patterns and trends outside of this.
Liz Roman:So fitmomsociety.com.
Liz Roman:And pattern three.
Becca Chilcz:Yes.
Becca Chilcz:So pattern three is an anemia of chronic disease.
Becca Chilcz:So this is typically more of an inflammatory pattern.
Becca Chilcz:You have iron, but inflammation ultimately locks it inside a storage,
Becca Chilcz:and it's an inflammation problem, not really an iron problem here.
Becca Chilcz:So here you're gonna see ferritin is gonna be normal or high.
Becca Chilcz:Serum iron and saturation will be low.
Becca Chilcz:Total iron binding capacity and UIBC will be low.
Becca Chilcz:We will usually see CRP, and we also test ESR, uh, sedimentation rate.
Becca Chilcz:Those are often elevated.
Becca Chilcz:We want sedimentation rate under a 10.
Becca Chilcz:Usually conventional's not gonna flag it until it's like a 25 or 30.
Becca Chilcz:We like it under a 10.
Becca Chilcz:CRP, again, is not the end-all be-all, because what CRP was designed
Becca Chilcz:to measure was it was designed to measure acute infections, injuries,
Becca Chilcz:and ultimately, you know, active large amounts of inflammation.
Becca Chilcz:If you have chronic low-grade inflammation, CRP might not
Becca Chilcz:be elevated, which is why we cannot lean on CRP by itself.
Becca Chilcz:We have to go off symptoms.
Becca Chilcz:We have to go off of other labs.
Becca Chilcz:And so CRP often is elevated, ESR is often elevated, but it might not be
Becca Chilcz:as much as you would think, right?
Becca Chilcz:Hemoglobin and hematocrit are often also low And in these situations,
Becca Chilcz:again, oral iron is not the fix here because it's not the problem.
Becca Chilcz:You usually have an issue where the inflammation is going on, and so ferritin
Becca Chilcz:is an acute phase inflammatory response in the body, and so your ferritin is going
Becca Chilcz:up and up, and you feel exhausted, and you feel like, "Okay, maybe because my iron
Becca Chilcz:is low, that's the answer." No, no, no.
Becca Chilcz:Iron is not low.
Becca Chilcz:Your body is responding to something.
Becca Chilcz:We have to figure out what it's responding to, right?
Becca Chilcz:This is an inflammatory process, and so in these cases, this is where we would
Becca Chilcz:be looking at, like, potentially a GI map test if there's nothing obvious going on.
Becca Chilcz:We would be looking at liver enzymes.
Becca Chilcz:We would be looking at our CBC.
Becca Chilcz:What's going on with the immune system?
Becca Chilcz:Do we have, you know, elevated or low white blood cells?
Becca Chilcz:Do we have neutrophils, lymphocytes, monocytes, all of our different types of
Becca Chilcz:white blood cells, are they dysregulated?
Becca Chilcz:Is vitamin D low?
Becca Chilcz:How long has this been going on?
Becca Chilcz:What I will often see is that ferritin will go acutely high when it is
Becca Chilcz:somewhat of an active infection.
Becca Chilcz:When the infection is ongoing and the immune system becomes exhausted, we over
Becca Chilcz:time start to see ferritin drop low.
Becca Chilcz:And so it kind of is like an indication that something is currently pretty acute,
Becca Chilcz:um, is what I actually tend to see.
Becca Chilcz:And then we also look to the liver, because the liver plays a really large
Becca Chilcz:role in essentially ferritin levels.
Becca Chilcz:And so if the liver is very stressed, if we're dealing with fatty liver,
Becca Chilcz:if we're dealing with liver burden, detoxification issues, we will also,
Becca Chilcz:also often see this go elevated.
Becca Chilcz:Sometimes I'll actually see ferritin go high and everything else is
Becca Chilcz:somewhat normal because it's more of a liver problem than it is
Becca Chilcz:even an iron or ferritin problem.
Liz Roman:Yeah, so let's talk about that.
Liz Roman:So what's happening in the liver is that we have hepcidin, which is iron
Liz Roman:gatekeeper, if you will, and this is a hormone actually made by the liver.
Liz Roman:Its job is to decide how much iron gets into your bloodstream and how
Liz Roman:much stays locked away in storage.
Liz Roman:And so when we have an acute infection or there's a chronic infection and
Liz Roman:the body knows that these pathogens, because there's a variety of pathogens
Liz Roman:that can feed off of iron, including parasites and candida, the body
Liz Roman:knows it's going to sequester it.
Liz Roman:So what happens here is hepcidin goes up, and it shuts down a
Liz Roman:protein called ferroportin.
Liz Roman:Ferroportin is basically the door that allows your iron to move out of your
Liz Roman:intestines into your blood, out of the storage in your liver into your blood,
Liz Roman:and from macrophages that recycle old blood cells back into circulation.
Liz Roman:So if we have elevated hepcidin, that hormone from the liver, this is shutting
Liz Roman:down ferroportin, so things aren't gonna go into transportation appropriately.
Liz Roman:We have less iron absorption and more trapped in storage.
Liz Roman:This is iron sequestration We're going to see that ferritin high
Liz Roman:typically, and then everything else, like Becca was saying, normal.
Liz Roman:And so again, this is really important, and this is where we're gonna look at all
Liz Roman:of those other markers that she mentioned in terms of the inflammatory markers,
Liz Roman:because those signals tell the liver to produce more hepcidin to lock iron up.
Liz Roman:So hepcidin is the iron gatekeeper.
Liz Roman:When inflammation rises, hepcidin rises as well and your body closes the gate.
Liz Roman:You absorb less iron from the gut, and you lock more inside storage.
Liz Roman:So again, this is really where, as you mentioned before earlier,
Liz Roman:Becca, it's trends over time.
Liz Roman:We don't wanna overreact to something, because typically
Liz Roman:we'll see this when people start with us or after an infection.
Liz Roman:You know, like, hey, they just got the flu, 24-hour bug, whatever this
Liz Roman:is, which is kind of silly, guys.
Liz Roman:Like, really don't do your labs close to being sick, because we
Liz Roman:are gonna see typically white blood cells are gonna be elevated.
Liz Roman:Other things are just gonna be off because there's an active infection.
Liz Roman:Sometimes we'll also see this with an injury, right?
Liz Roman:So injuries create inflammation in the body.
Liz Roman:It's a healing response that we need.
Liz Roman:And so I like to see at least a week, if not longer, maybe two, away from
Liz Roman:an infection or an injury inflammation that's, you know, again, more acute.
Becca Chilcz:Mm-hmm.
Becca Chilcz:So the next trend is what's called B12 folate anemia or macrocytic anemia,
Becca Chilcz:where red blood cells actually get too big but not enough, so there aren't
Becca Chilcz:enough of them, and they grow in size.
Becca Chilcz:And this is not iron.
Becca Chilcz:It's low B12 and folate and poor absorption issues.
Becca Chilcz:So you watch for kind of tingling and brain fog and memory changes.
Becca Chilcz:MCV is a big marker that we'll look for.
Becca Chilcz:I actually see this, I would say, in more labs than not.
Becca Chilcz:Like MCV in almost all of my labs that I look at is high.
Becca Chilcz:So in this situation, a lot of times you will actually see red blood
Becca Chilcz:cells, hemoglobin, and hematocrit low.
Becca Chilcz:Iron and ferritin are normal.
Becca Chilcz:Homocysteine can be high.
Becca Chilcz:Sometimes it can also be low, too.
Becca Chilcz:This is like … This is a tricky one, 'cause homocysteine can be low when
Becca Chilcz:there's a B12 folate need, and it can be high when there's a trimethylglycine need.
Becca Chilcz:Like, it is kind of dependent.
Becca Chilcz:Um, so homocysteine we want around, like a 7.2 or so.
Becca Chilcz:If it's in the 8, 9, 10 plus, definitely a need for homocyst-
Becca Chilcz:I'm sorry, for B12 and folate.
Becca Chilcz:When it's low though, a lot of times there's deficiencies as
Becca Chilcz:well, so something to consider.
Becca Chilcz:And then MMA, if it is measured, a lot of times will be high.
Becca Chilcz:So in this situation, it's a little bit different of an
Becca Chilcz:anemia, um, and still a problem.
Becca Chilcz:It will still reflect in red blood cells, hemoglobin, hematocrit, these
Becca Chilcz:different things, but it typically is not reflected in iron and ferritin.
Becca Chilcz:Um, so just something to watch out for in terms of another
Becca Chilcz:trend that we will sometimes see.
Becca Chilcz:And then the fifth one is
Liz Roman:It is important, though, to check your folate and check your B12.
Liz Roman:And by the way, guys, B12 also has a very wide range on- Yes … LabCorp.
Liz Roman:It's, like, laughable.
Liz Roman:I had someone on Instagram the other day like, "Oh, my B12
Liz Roman:is, like, 470-something." I was like, "Yeah, that's great.
Liz Roman:That's about half of where we wanna see it, around 900.
Liz Roman:850 to 950 for B12 is what we wanna see.
Liz Roman:And here's a caveat.
Liz Roman:You need to stop your B12 or all, you know, biotin, any B vitamins 72
Liz Roman:hours or three days prior to your lab draw because it's not only gonna
Liz Roman:throw your B12 off, and some people freak out, like, their B12 is 1,600.
Liz Roman:It's like, okay, this is a water-soluble vitamin, and you took that.
Liz Roman:You didn't, you know, pause it for three days before it's going to show high.
Liz Roman:You're gonna pee it out.
Liz Roman:Don't freak out.
Liz Roman:It's fine.
Liz Roman:Obviously, if you're not taking B12 and B12 is elevated, that's a
Liz Roman:different cause for concern, right, and you're seeing that pattern.
Liz Roman:Uh, but I think this is wise to not only look at your iron panel with everything
Liz Roman:and your complete blood count with everything, the CRP, the homocysteine.
Liz Roman:Look at everything else, a full thyroid panel.
Liz Roman:All of it matters because it can really tell us a story that we can
Liz Roman:start to piece together, you know, that puzzle for you essentially.
Liz Roman:So a lot of times we talk about deficiency, we talk about low
Liz Roman:iron, low ferritin, all of that.
Liz Roman:And again, we've helped you now distinguish, do I have a true deficiency?
Liz Roman:Is my body locking iron up?
Liz Roman:Maybe there's inflammation, infections going on here.
Liz Roman:Maybe it's more of, you know, the B12, folate, uh, anemia.
Liz Roman:There's multiple patterns.
Liz Roman:But what about over like over, uh, high iron, right?
Liz Roman:And so when we look at this and everything is spilling over, um, this is overloaded.
Liz Roman:That's the word I was looking for.
Liz Roman:Uh, hemochromatosis.
Liz Roman:And so your body absorbs iron and it can't stop.
Liz Roman:Now, there's genetic factors here to this.
Liz Roman:Um, and ferritin alone will totally miss this.
Liz Roman:You need to have that saturation.
Liz Roman:Um, and that's really gonna be the tell here.
Liz Roman:So if you're looking at your iron saturation, hemochromatosis,
Liz Roman:like a true hemochromatosis, you're gonna see that over 45%.
Liz Roman:You are likely going to see high iron, high ferritin, low total
Liz Roman:iron-binding capacity, but you can't say this is hemochromatosis if
Liz Roman:you're not looking at the saturation.
Liz Roman:So women will have this miss for decades.
Liz Roman:I remember, Becca, we won't share the client's name live, but we had a
Liz Roman:client with this pattern, and she was having a lot of heaviness in her legs.
Liz Roman:She was getting winded she-- when she would go up the stairs.
Liz Roman:And as soon as we had her go and donate blood, a lot of that improved.
Liz Roman:Um, and so this is something that, you know, we do wanna watch out for.
Liz Roman:Uh, if you do have iron overload, and this is more genetic in your
Liz Roman:family, then there's, you know, ways you need to watch how much iron, you
Liz Roman:know, rich foods you're consuming.
Liz Roman:Not cooking in an iron skillet.
Liz Roman:Uh, the cast iron skillet, specifically when there's acid added to it,
Liz Roman:like a tomato sauce, it's going to leach more iron into your cooking.
Liz Roman:You would want to, you know, think about avoiding supplements that have
Liz Roman:iron in them and giving blood, donating blood, and also potentially using
Liz Roman:lactoferrin because that can help with transporting things appropriately, uh,
Liz Roman:and helping your body process that.
Liz Roman:Lactoferrin also has a lot of great benefits though, even for your
Liz Roman:gut microbiome, uh, the epithelial cells, healing up leaky gut.
Liz Roman:So if we're seeing on labs high zonulin, high calprotectin, a lot of inflammation
Liz Roman:in the gut, lactoferrin can be really great, um, actually for most cases.
Liz Roman:Again, this is not medical advice.
Liz Roman:We would wanna evaluate this, you know, person to person.
Liz Roman:And then in our guide, so if you wanna click the link in the show
Liz Roman:notes for Uh, you know, our iron anemia guide, we do talk a little
Liz Roman:bit about why we avoid oral iron, and I'll give it to you straight here.
Liz Roman:Simply, it can feed pathogens, and it's very harsh on the gut.
Liz Roman:We can get into the debate about different types of iron and how that
Liz Roman:goes and, you know, sometimes there are situations where we do need oral iron,
Liz Roman:and in that situation, we would want iron that's very gentle on the gut.
Liz Roman:We would wanna have it be paired with copper.
Liz Roman:Copper deficiency is a big thing with iron deficiency as well, and it
Liz Roman:really impacts your body's ability to utilize the iron appropriately.
Liz Roman:So vitamin C, copper, stomach acid support, those are three big players when
Liz Roman:we're seeing a true anemia, uh, you know, iron anemia, ferritin is low, all of that.
Liz Roman:We want to make sure that we're supporting your body.
Liz Roman:But on the flip side, if you have too much iron, right, then you
Liz Roman:have to go the opposite direction.
Liz Roman:Um, and again, you would wanna obviously be partnering with your
Liz Roman:doctor or your practitioner for your individualized protocols here and
Liz Roman:how often you need to donate blood.
Liz Roman:I know at Vital Medical, our nurse practitioners and our partners there
Liz Roman:are fantastic with this, where we'll have clients donate blood, lab,
Liz Roman:uh, draw labs at about six weeks.
Liz Roman:Conversely, iron infusions, if that's the case, I have a few of those right now
Liz Roman:where we truly needed to have, their iron anemia was gone that far, an infusion,
Liz Roman:then we're checking again, typically at four weeks, this is what I'm sending them
Liz Roman:in for, and we're monitoring symptoms between, and we're still using things
Liz Roman:that are going to support them in terms of the oral iron strips, so the Kaave Melts.
Liz Roman:Those have folate in them and then iron, which is great, very gentle.
Liz Roman:It's going sublingual through the tongue and just melts in your
Liz Roman:mouth, tastes like raspberry.
Liz Roman:I don't personally love it.
Liz Roman:A lot of people haven't complained about it.
Liz Roman:It's not terrible, but it has a metallic taste to it.
Liz Roman:Mm-hmm.
Liz Roman:Uh, and then lactoferrin.
Liz Roman:So lactoferrin, I have a lot in a lot of my cases.
Liz Roman:Um, I am starting it myself because I have a l- bit low ferritin, uh,
Liz Roman:and everything else is fine, but I'm seeing my ferritin, I think it was 42.
Liz Roman:I don't have heavy periods, but I wanna get ahead of this.
Liz Roman:I do see other markers that are depleted, and that has to do with previous stress
Liz Roman:of moving and all of that, not eating enough for sure, as I'm learning, as
Liz Roman:I'm retracking my food and all of that.
Liz Roman:But we often don't realize how much we burn through when we are stressed.
Liz Roman:And so if you're somebody who has this pattern and you, you know,
Liz Roman:kinda have this tendency to fall on that low side Here's the real truth.
Liz Roman:You're probably going to have to work hard to get this up and keep it up.
Liz Roman:Some people say, "Well, can't we take, you know, just everything through food?
Liz Roman:And why do we have to use so many supplements?" And I get it, but when
Liz Roman:you're in a state of dysfunction, there's a reason for a season.
Liz Roman:And when we know the person's genetics, we know they've had a compromised
Liz Roman:gut for many years, maybe a lot of stress, trauma, dysregulation of
Liz Roman:nervous system, whatever it might be Then this is where supplements come to
Liz Roman:play to be supplemental to your diet.
Liz Roman:Yes, we take a diet first approach, and you should take a diet first approach.
Liz Roman:However, sometimes that's not enough, and so you need to
Liz Roman:rebuild your stomach acid levels.
Liz Roman:We love the HCL Guard by HealthyGut or Betaine HCL and
Liz Roman:our stomach acid resource pack.
Liz Roman:We have a ton of different ways that you can support that with bitters and
Liz Roman:apple cider vinegar and all those things.
Liz Roman:I like to just keep it simple and take a capsule.
Liz Roman:Then you would wanna think about vitamin C, so vitamin C rich
Liz Roman:foods, vitamin C with your meals.
Liz Roman:So you could either take this in a liquid form, a powder form.
Liz Roman:I prefer buffered vitamin C. It's easier on the gut.
Liz Roman:But for me personally, if you've watched my stories over the past almost
Liz Roman:three years now, I believe maybe…
Liz Roman:No, two years, going into my third year, we've taken camu camu every day.
Liz Roman:My son takes it as well.
Liz Roman:It's great, uh, f- source of natural vitamin C, naturally higher in iron,
Liz Roman:so I include for my iron anemia gals.
Liz Roman:Put it in your smoothies.
Liz Roman:Put it in your drink.
Liz Roman:You can use a camu camu powder.
Liz Roman:Those are very cheap and affordable.
Liz Roman:They do have, like, a little bit of a sour taste.
Liz Roman:Sometimes I just found that they were kinda chalky, so I opt to just keep the
Liz Roman:IO1 dropper in, and it's just so easy.
Liz Roman:My kids don't even notice that it's going in their drinks.
Liz Roman:Um, so just remember there's a lot of things that we can do here, and
Liz Roman:then it's important that you recheck.
Liz Roman:So look at your labs, see the pattern, identify what you need,
Liz Roman:implement that, and take consistent action for at least four weeks.
Liz Roman:Recheck.
Liz Roman:Watch your menstrual cycles too.
Liz Roman:So if you are somebody who is having those really heavy bleeds, go into the
Liz Roman:guide and look at everything else we talk about related to your thyroid.
Liz Roman:Iodine's a crucial player here because that regulates growth, and we know that
Liz Roman:typically when iron is low, we're gonna see iodine deficiency and typically
Liz Roman:more on the slow hypothyroid, uh, side.
Liz Roman:So Beck, I don't know if you wanna add anything to that, but this
Liz Roman:is definitely a broader, complex picture, and sometimes we do have
Liz Roman:to work hard to get these stores up.
Becca Chilcz:Yeah, and I, I think the last piece that we haven't
Becca Chilcz:expanded on too much is around how ferritin can a lot of times be because
Becca Chilcz:of mitochondrial and cell issues.
Becca Chilcz:So iron isn't just for making red blood cells.
Becca Chilcz:Like, it's required for the raw material inside of individual cells for jobs that
Becca Chilcz:have nothing to do with oxygen support.
Becca Chilcz:One of them is in the electron transport chain, which is basically
Becca Chilcz:how your cells make energy.
Becca Chilcz:And so if there is a lot of struggle happening at a cellular level due
Becca Chilcz:to, you know, immune based issues, chronic stress on the system, the
Becca Chilcz:iron is going to be essentially worked through, and mitoch- mitochondria
Becca Chilcz:can't run that chain efficiently.
Becca Chilcz:And so your cells make less energy regardless of what hemoglobin looks like,
Becca Chilcz:and that's why people a lot of times don't have hemoglobin and hematocrit
Becca Chilcz:issues, but, like, they're exhausted, they have brain fog, they're cold.
Becca Chilcz:Because if their ferritin's low A lot of times it's a cellular
Becca Chilcz:problem, not necessarily an iron and iron storage problem.
Becca Chilcz:And iron's also a cofactor, which we didn't talk too much about, but it's
Becca Chilcz:a cofactor for enzymes outside the mitochondria that convert T4 to T3.
Becca Chilcz:So it's needed for enzymes that essentially synthesize dopamine
Becca Chilcz:and serotonin, and low ferritin will contribute to sluggish thyroid
Becca Chilcz:conversion, low mood, low motivation.
Becca Chilcz:So it's kind of this vicious cycle of, like, it affects a lot of different
Becca Chilcz:systems, and ferritin is a reserve.
Becca Chilcz:It's not real-time measurement like iron is, you know?
Becca Chilcz:So it tends to drop well before your hemoglobin or MCV or these other
Becca Chilcz:markers, and the body prioritizes iron for hemoglobin production
Becca Chilcz:above almost everything else, so it will drain ferritin, essentially
Becca Chilcz:to protect red blood cell output.
Becca Chilcz:So we're looking at iron, we're looking at the gut, we're looking at all these
Becca Chilcz:things, and that's not wrong, but sometimes it gets to a place where we
Becca Chilcz:have to look at the cellular health and what ultimately is depleting the
Becca Chilcz:cellular health, which can be, you know, chronic viral, it can be GI
Becca Chilcz:issues, it can be chronic stress, it can be chronic undereating, right?
Becca Chilcz:There's so many things that can stress out a system, and that's a
Becca Chilcz:case-by-case basis of what we look for.
Becca Chilcz:But this was something that was really interesting that we kind
Becca Chilcz:of, uh, came upon a little bit more recently on with the mitochondria
Becca Chilcz:being such a big piece of low ferritin and having to be addressed as well.
Becca Chilcz:Um, but yeah, it's why you have to look at things as a whole.
Becca Chilcz:You can't just isolate an iron panel.
Becca Chilcz:You can't just isolate ferritin.
Becca Chilcz:Like, you have to look at the entire system.
Becca Chilcz:It's why we run so much blood work.
Becca Chilcz:It's why we look at health history and dive deep into this with people.
Becca Chilcz:Because again, you're just not gonna get it anywhere else.
Becca Chilcz:Like, we've had the … Liz and I had this conversation offline.
Becca Chilcz:People are like, "I learned more in this conversation than I've
Becca Chilcz:learned in months/years working with different doctors." And
Becca Chilcz:it's, again, no fault to people.
Becca Chilcz:Like, some people, it's just not their expertise.
Becca Chilcz:It's not what they've learned.
Becca Chilcz:It's not that they don't have the time, right?
Becca Chilcz:I mean, I had a client a wh- a while ago, I remember, and she had a very
Becca Chilcz:clear hemochromatosis pattern, and I told her to go to her, her hematologist.
Becca Chilcz:Mm. And she came back and said the hematologist basically said, "We're
Becca Chilcz:not gonna do anything until it gets worse." And so, um, you know, you
Becca Chilcz:kinda have to fight for yourself and find your own answers sometimes,
Becca Chilcz:which is what our team helps with.
Becca Chilcz:Uh, and so we advise, obviously, utilize things that are helping with, you know,
Becca Chilcz:not absorbing so much iron, like Liz went through, um, and then giving blood.
Becca Chilcz:Some people need to give blood every month, every other month.
Becca Chilcz:Like, sometimes it needs to be a little bit more regular,
Becca Chilcz:especially if it's gotten kinda bad.
Becca Chilcz:Um, but yeah, that heaviness, that leg heaviness, that feeling like you're
Becca Chilcz:huffing and puffing, like, it almost feels like you're working through quicksand, um,
Becca Chilcz:can be really common with hemochromatosis 'cause iron is very heavy on the system.
Becca Chilcz:When it gets too high, it stresses out the liver a ton.
Becca Chilcz:Um, so yeah, it's, uh, we gotta find our own answers sometimes, and
Becca Chilcz:that's what we do the podcast for.
Becca Chilcz:That's what we try to help you guys with.
Becca Chilcz:Um, and if you want those answers and you feel like you're not getting them,
Becca Chilcz:go to the show notes, book a call with our team, set up a lab review with us.
Becca Chilcz:We're more than happy to go through this all with you and help you
Becca Chilcz:understand what your patterns are.