Artwork for podcast Beyond the Abstract
The Placenta: Here for a Good Time, Not a Long Time
Episode 2821st September 2022 • Beyond the Abstract • Beyond the Abstract
00:00:00 00:16:19

Share Episode


Preeclampsia is a pregnancy disorder characterized by high blood pressure and contributes to significant fetal and maternal deaths. However, what exactly causes preeclampsia is unclear. It's thought that preeclampsia is caused by placental dysfunction - specifically, the ability of specialized fetal cells called trophoblasts to replace and remodel maternal blood vessels. In this episode of Beyond the Abstract, Derek and Dan discuss a new paper that describes how trophoblasts "mimic" blood vessels in order to establish the maternal-fetal connection in the placenta and how this process may go awry in preeclampsia.

Read more about this research in this blog post.

Sung et al. VE-cadherin enables trophoblast endovascular invasion and spiral artery remodeling during placental development. eLife, April 2022. DOI: 10.7554/eLife.77241

The information presented here is not medical advice. Consult your physician on any questions regarding your personal health.