You're listening to the Tracking Wisdom Podcast, exploring the universal
2
:truths that we see woven through culture,
consciousness, and the human experience.
3
:Ryan: Good morning everybody, and
welcome back to another episode
4
:of the Tracking Wisdom Podcast.
5
:I'm Ryan,
6
:Peter: I'm Peter,
7
:Ryan: and today I wanted to talk about Dr.
8
:Anita Goel.
9
:So this is a physicist and MD
that we came across in yet another
10
:Essentia Foundation interview.
11
:Dr.
12
:Anita Goel, MD PhD, she's a physicist
and world renowned expert and pioneering
13
:in the emerging field of nano physics.
14
:And she is a physicist by training
and has been enamored or, inspired
15
:by, nano machinery, nanotechnology and
in particular she has a focus on DNA
16
:transcription and DNA polymerase as a
nano machine, and has some theories around
17
:how it might be interacting with quantum
mechanics and how using the biological
18
:system, the living systems, which in
are inherently open versus the classical
19
:physics and the work that's been done
historically on closed systems, how
20
:studying that may help us make strides in
closing the gap that Einstein, Schrodinger
21
:Penrose and the like have all acknowledged
that there's something missing,
22
:something not quite complete about our
understanding of quantum mechanics.
23
:And she has a, a theory that studying
this understanding, not only the
24
:nanotechnology itself, but essentially
if her theories are proven to be, sound,
25
:that we could use that as a quantum
sensor . That we could use biological
26
:systems and their interaction with
the quantum field quantum mechanics to
27
:detect those interactions and further
our understanding of quantum mechanics.
28
:Is that a fair way of
29
:Peter: Yeah, I think that the point
of the idea of the quantum detector is
30
:that the system, so the D.N.A./D.N.A.
31
:polymerase experimental system,
can be developed into, technology
32
:that can be used to create the
equivalent of a double slit experiment
33
:. Ryan: Right.
34
:Peter: So, as you were saying, you know,
she points out that, quantum theory is
35
:incomplete, and a way of reducing the
incompleteness is to turn away from
36
:inanimate closed systems and start
to look at living systems, because
37
:it'll just give us a different view.
38
:I mean, everything that we
know is from experimentalists.
39
:Well, I mean, not just
experimentalists theorists too, right?
40
:Mm-hmm.
41
:Ignoring living systems, because
living systems are too messy.
42
:And, because of her work in Nanosystems
and her ability to manipulate living
43
:systems and make them tractable
to experimentation, she's like,
44
:oh no, they're not too messy.
45
:And I think part of her.
46
:Thing too is that the apparent messiness,
may have to do with the intrinsic
47
:involvement of quantum effects.
48
:Ryan: Hmm.
49
:Peter: She says some clearer things
about quantum effects and living systems,
50
:which are really interesting, but, the
big goal, at least that they're talking
51
:about in this conversation, is to create
something like the double slit experiment.
52
:Something that clearly demonstrates the
properties of quantum physics, but using a
53
:completely new kind of experimental setup.
54
:And it's not to duplicate the, mm-hmm.
55
:Double slit, but an experiment that
has the impact of the double split
56
:experiment and that it's a very
clear demonstration of, well the
57
:double split experiment demonstrates
the kind of dual nature of light as
58
:wave and particle at the same time.
59
:The double slit experiment
demonstrates ensemble behavior.
60
:Ryan: Mm-hmm.
61
:Peter: And so, she's looking for a kind
of experiment to do in a biological
62
:system, specifically her nanotech
setup with DNA and DNA polymerase,
63
:and she says that the roadmap is
there, needs a lot more resource to
64
:refine the resolution of the system,
65
:Ryan: mm-hmm,
66
:Peter: in order to set up the
correct kind of experiment.
67
:Ryan: Yeah.
68
:Peter: And then goes far field
later on into her own kind
69
:of intuitive understanding
70
:of the nature of, I guess
reality and consciousness.
71
:Ryan: Yeah.
72
:Peter: To some extent.
73
:Ryan: Yeah.
74
:And one thing that I did find interesting
is how, number one, she presented
75
:the idealist paradigm, but, as we had
mentioned in previous episodes, it
76
:seems that the scientists that we've
come in contact with that are on the
77
:idealist side of the conversation,
all appear to have had a precipitating
78
:experiential event, that then led
them to use their scientific skills
79
:and knowledge to pursue this avenue.
80
:And she, from all accounts that we can
tell, is the first one that I can recall
81
:that came to this purely scientifically.
82
:Peter: Intellectually.
83
:Ryan: Intellectually and theoretically,
that we keep bumping up against walls with
84
:the classical approach and the materialist
paradigm, specifically around the quantum
85
:measurement problem and the hard problem
of consciousness that , by flipping
86
:that on its head and starting with the
consciousness first paradigm, these
87
:things become more readily answerable.
88
:But she's very adamant
about using rigorous.
89
:Yeah.
90
:scientific approach and data.
91
:And she has a very high
bar for her research.
92
:She was saying she has high hopes for it,
but she's also her highest critic where
93
:she's, very, stringent on making sure that
the output of this research is rigorous.
94
:And that, it also encompasses
and answers all the classical
95
:things that we already know.
96
:That all has to be part of what comes
out of the experiment and the theory.
97
:She's particularly interested
in the medicine side of things.
98
:We've all benefited from, utility of
quantum mechanics with the smartphones
99
:and things like that, quantum computing.
100
:Peter: In terms of healthcare,
CAT scans, MRIs, x-rays.
101
:Ryan: Sure.
102
:Right.
103
:Peter: Those are, yeah.
104
:Ryan: And, she made a very specific
comment that medicine is essentially
105
:still stuck in the biochemical.
106
:Peter: So yeah, I mean it's this
kind of roadblock of knowledge
107
:or dead end that we've hit just
I think in knowledge in general.
108
:Ryan: Right.
109
:Peter: There's a lot of discussion
about how, as you said, the founders of
110
:quantum mechanics were very frustrated
with the incompleteness of the theory.
111
:Which is what Schrodinger's cat is,
is a satirizing and exaggeration
112
:of the problems of the theory,
the shortcoming of the theory.
113
:And that, it's not just physics
that hit that roadblock.
114
:Ryan: Right.
115
:Peter: Like all the other disciplines,
like medicine is limited because
116
:essentially medicine is completely
dependent on chemistry and physics.
117
:Ryan: Right.
118
:Peter: You know, she was a physician
who decided to become a physicist.
119
:And her vision is that by breaking
through this roadblock in physics,
120
:we can open huge horizons in, in
medicine, healthcare, and, and beyond.
121
:Ryan: Right.
122
:Peter: Because of course, every time
you crack the limitations of physics,
123
:you open up incredible new technologies.
124
:So yeah, she's a very, I
think, what's the word?
125
:Free thinker?
126
:Like visionary.
127
:Ryan: Mm-hmm.
128
:Peter: Very visionary, but, also very,
very committed to grounding herself.
129
:And she's like, I have to play like a
child and dream big and then constrain
130
:myself to what can we measure.
131
:Ryan: Right.
132
:Peter: And how can I figure
out how to measure it?
133
:And she just goes back and forth
between these, these states.
134
:Which kind of reminds me of Hoffman.
135
:Ryan: Mm-hmm.
136
:Peter: Talking about meditating,
137
:Ryan: yeah,
138
:Peter: and then doing science.
139
:Ryan: Right.
140
:Peter: Right?
141
:And swinging between those states.
142
:So you already mentioned,
open versus closed systems.
143
:Ryan: Yeah.
144
:Peter: Physical experimental systems
being inanimate and closed and being
145
:at or near equilibrium, as she says.
146
:And then living systems are open systems
that are, never very near equilibrium.
147
:They're constantly building.
148
:Ryan: Yeah.
149
:Peter: She uses the term negentropic,
which I just thought was great.
150
:And she talks about current physics and
future physics, current physics being
151
:matter and energy and future physics
adding information into the equation,
152
:that's her vision is to break through.
153
:And her intention is to refine this
nanotech biological system that she works
154
:with, to sufficient resolution to perform
this experiment; we don't know what it
155
:would be, that will crack the barrier
156
:Ryan: mm-hmm
157
:Peter: of quantum physics.
158
:Ryan: So she, specifically about the
DNA polymerase, is enamored by both
159
:the energy efficiency of the molecule,
and its processing volume and speed.
160
:She speaks to how the DNA polymerase
as it's transcribing and building
161
:does a hundred billion computational
steps per 10 milliseconds.
162
:And will be able to error correct
itself when there's mutations.
163
:She does talk a little bit about whether
those mutations are random versus
164
:environmental or quantum, and this is
part of where she's going with this is
165
:to determine if there is a consequential
quantum and environmental element , that's
166
:where information comes in, versus
something that's Darwinian and is random.
167
:Peter: So you were starting to say
that she's interested in the polymerase
168
:as a machine, as an nano machine.
169
:Ryan: Right.
170
:Peter: And she suspects that the way
DNA polymerase works, may be exploiting
171
:quantum effects, in a non-trivial
way, for function and efficiency.
172
:So you named the function of calculate
a hundred billion steps per base pair.
173
:So each time the polymerase reads a
base of DNA, it needs to perform a
174
:hundred billion computational steps
in order to find the correct base to
175
:attach to the base that it wants to
connect, to build the matching strand.
176
:But the other piece of it is that,
the polymerase is also acting as a
177
:molecular motor, because it's moving
mechanically along the DNA strand.
178
:And as a molecular motor, it's 99.9%
179
:efficient.
180
:And she says that, compared to 20 to
40% for an internal combustion engine.
181
:Ryan: Right.
182
:Peter: That these two extraordinary
features of the nano machine suggest to
183
:her that something strange is going on,
184
:Ryan: right,
185
:Peter: that's beyond the
purview of just regular physics.
186
:And so she suspects that there are quantum
effects happening, or that the polymerase
187
:is exploiting quantum effects in some
ways, to give itself these superpowers.
188
:Ryan: And I think that those are
both indicators, and potential uses.
189
:Right?
190
:If we understand better how
it manages to achieve a 99.9%
191
:energy efficiency, that that could help
us in the material world to achieve
192
:better efficiencies in energy usage.
193
:And then she did say specifically,
the non-trivial quantum effects is the
194
:question that starts the whole thing.
195
:The effects of the quantum
collapse, and the coherence,
196
:historically has been dismissed as
trivial to the biological system.
197
:Her first step in pursuing this
theory is to determine does the
198
:collapse happen before the end of
the computational phase, or after.
199
:So if it extends long enough, then
we can interpret that there is a
200
:potential for non-trivial impact of
quantum mechanics, versus if it happens
201
:so fast that it would be trivial.
202
:Peter: So does quantum ness
or superposition exist in this
203
:system, of DNA and polymerase,
204
:Ryan: long enough
205
:Peter: long enough to be relevant
to, basically for the time
206
:needed to read a base pair,
207
:Ryan: right.
208
:Peter: Which, as you
said, is 10 milliseconds.
209
:So she has a specific timeframe for
which she needs to demonstrate the
210
:sustained coherence of a quantum state.
211
:Ryan: Yes.
212
:Peter: I get that there's a thing
called superposition, which means
213
:you are two things at the same time.
214
:If you're a cat, you're alive and dead
at the same time, if you're a photon,
215
:you're a wave and a particle at the
same time, and then at some point
216
:that superposition collapses or that
quantum coherence has a decoherence.
217
:Ryan: Mm-hmm.
218
:Peter: And when that happens, now you've
gone from an indeterminate state of
219
:being both things to the determinate
state of being a single thing.
220
:Ryan: Yeah.
221
:Peter: Okay, now here's the question.
222
:Is the coherence very short or very
long ? Because, I read somewhere that
223
:the reason that we can see photons
collapse is because there are so many
224
:of them that the odds of some collapsing
at any given time are, are high.
225
:But that the the timeframe of
decoherence is extremely long.
226
:Ryan: Mm.
227
:Peter: Like thousands
or millions of years.
228
:And the, the only reason that we
see the decoherence is because
229
:of these huge numbers of events
that we're we're considering.
230
:On the other hand, I thought I
understood that superposition only
231
:happens for infinitesimally small
amounts of time before collapse.
232
:And then Penrose says it's all about,
okay, now we're in the measurement
233
:problem because we're saying, oh, it's
not about the time, it's about whether
234
:there's an observer or not, because the
observer is what creates the collapse.
235
:And Penrose says, no, it's not
about an observer, that's garbage,
236
:gravity is what creates the collapse.
237
:And i'm not even sure how
that happens, because does,
238
:Ryan: well I think he was, he was
talking about how Mass had impact on the
239
:Peter: so the mass of the thing
allows you to calculate how
240
:long the coherence will be.
241
:Ryan: That's what he said.
242
:Peter: Right.
243
:Ryan: Yeah.
244
:Peter: So is he saying it's
very short because photons
245
:Ryan: are small.
246
:Peter: Are small so they have very low
247
:Ryan: or is it the other way around?
248
:Peter: Gravitational effects, so
therefore they immediately collapse.
249
:Ryan: Think it's the other way
250
:Peter: so if you're a planet
251
:Ryan: saying if, if it's
big, it collapses quickly,
252
:Peter: immediately, right?
253
:If you're a planet, you're just a
planet, you're not like two kinds
254
:of planet, you're not, you're not
dead and alive at the same time.
255
:But if you're a tiny
photon, you maintain your
256
:Ryan: quantum state for
a long period of time,
257
:Peter: for a long period of time.
258
:Ryan: I think that's what he was saying.
259
:Peter: Right, so what she's saying
is that the quantum state of the
260
:DNA polymerase, DNA and polymerase
complex has to be long enough, has
261
:to be at least 10 milliseconds.
262
:If she can demonstrate that, then
she knows, okay, that's a relevant
263
:Ryan: right
264
:Peter: timeframe.
265
:For what we're looking at.
266
:So we can use this for
a quantum experiment,
267
:Ryan: it at least says that there's.
268
:Potential for meaningful impact.
269
:Peter: Meaningful interaction.
270
:Ryan: Right.
271
:Peter: Because if it was shorter
than that, then there's no way the
272
:quantum effect could be impacting
the reading of the base pair.
273
:Ryan: Right.
274
:Peter: She cites some other examples
where, so this is leading edge technology,
275
:experimentalism, or whatever, that
it's not, it's very controversial.
276
:Ryan: Mm-hmm.
277
:Peter: Still, but there are
couple of studies suggesting,
278
:the presence of non-trivial
quantum effects in living systems.
279
:And she says there's some studies in
bird navigation, I believe it's bird
280
:navigation, and in photosynthesis,
which we haven't looked up with this.
281
:But she does indicate that,
she's not the only one looking at
282
:quantum effects in living systems.
283
:But it, it sounds like she's
the one who's most committed to
284
:creating the definitive experiment.
285
:Ryan: Right.
286
:Peter: And she feels like she has
a system that she's working with
287
:that she can continue to refine
in order to accomplish that.
288
:Ryan: Right, she has the roadmap.
289
:She seems to understand what
needs to happen, but that the
290
:tools and measurements, still
need resolution improvement in
291
:order to get to what she needs.
292
:And she cited resource as a main
component of that of course.
293
:And so she didn't talk
specifically about consciousness,
294
:except really at two places.
295
:At the beginning when she was
describing the idealist paradigm, and
296
:suggesting consciousness first and
everything else comes out of that.
297
:But then at the end, she went through
her theory and what her intent for her
298
:experiments and pursuit is, and then
started to describe what she was calling
299
:the fifth industrial revolution driven
around AI, which is obviously continuing
300
:to develop, got into taking off her
scientific hat and putting on her humanity
301
:hat that, as we start to grapple with will
the electronic systems become conscious,
302
:what is the definition of consciousness?
303
:The pursuit of understanding consciousness
has been there for a long time.
304
:It's the hard question that periodically
I think we poke at, but hasn't had
305
:the urgency, until now, where we have
now a compelling reason to have to,
306
:really understand and define what is
consciousness, what defines consciousness.
307
:And beyond that, if we take
the materialist paradigm to its
308
:natural conclusion, if fact, the
machines take over human activity,
309
:where is the purpose, right?
310
:What, where do we find the
value and purpose in life?
311
:And that the materialist paradigm
sort of shuts it down is basically
312
:Peter: right
313
:Ryan: being end.
314
:Peter: Right.
315
:And we heard this from Faggin as well.
316
:Ryan: Yeah.
317
:Peter: That if you adhere to the materials
paradigm, which is what is creating AI,
318
:Ryan: right,
319
:Peter: you maintain this mechanistic
perspective until the mechanisms
320
:exceed the capabilities of humans.
321
:And now the mechanisms have
more value than humans.
322
:And now humanity has destroyed itself
because it's created machines that
323
:have more value than their creators.
324
:Ryan: Right.
325
:Peter: And so, that fact of obvious
conclusion, compels us to shift
326
:our understanding of consciousness.
327
:And not to just change your minds,
but to really understand, to really
328
:answer the question as, you're saying.
329
:So there's this very dystopian, gloomy
message there, but at the same time, the
330
:converse is, and this is also I think
something that's we've heard consistently
331
:from people exploring these kinds of
ideas, that freeing ourselves from the
332
:materialist paradigm will open infinite
horizons, and usher in a golden age of
333
:combined spiritualism and technology.
334
:Ryan: Yeah.
335
:Peter: And that's something that she
talks pretty strongly about is, we're
336
:really past the point where we can
talk about oh, it's just technology,
337
:or, oh, it's just spiritualism.
338
:She points out that there's thousands of
years of, what I'm going call non-material
339
:technology, spiritual cultures and systems
and, and disciplines, that are focused
340
:on the non-material aspect of reality.
341
:But that they generally come at
the expense of material progress.
342
:And I think this is maybe
a trivial illustration?
343
:I don't know if it's a good illustration.
344
:But the apparent material dominance
of the West over the East, where
345
:these spiritual traditions are
stronger and more developed.
346
:And she also mentions indigenous peoples.
347
:Ryan: Mm-hmm.
348
:Peter: So there's another example
of like, yeah, I think you can point
349
:to pretty poor material success in
those cultures, even though there
350
:may be exceptional spiritual success.
351
:Ryan: Right.
352
:Peter: And that we shouldn't
be having either or.
353
:Ryan: Mm-hmm.
354
:Peter: You know, we shouldn't be
materially supreme and wealthy and have
355
:amazing technology, and chronically
depressed and anxious and troubled,
356
:Ryan: right,
357
:Peter: and sleepless.
358
:And that it's now is the time to
understand the relationship of
359
:the material and the non-material.
360
:Ryan: Mm-hmm.
361
:Peter: And I, I was gonna say exploit,
which is not the right term…
362
:leverage the understanding of both,
to create this abundance and harmony.
363
:Ryan: Yeah, I mean that, that has
been a consistent message amongst, I
364
:don't know if it's been explicit with
all the thinkers we've been exploring
365
:here, but definitely I know this one,
and I think others have described it
366
:as well, which is, the the historical
mystical philosophy has been, there's
367
:an interconnectedness with all things.
368
:And the historical materialist perspective
has been compartmentalizing everything.
369
:And I think it sounds like the idealist
philosophy has an expected outcome that,
370
:if proven, the widespread awareness and
understanding of our interconnectedness
371
:with each other, and the planet, and
all things will lead to better ethics,
372
:geopolitical and business practices, that
by and large society will be constructive.
373
:Peter: Yeah.
374
:I mean, it will transform
our concept of values,
375
:Ryan: right?
376
:Peter: Values and value.
377
:Ryan: Mm-hmm.
378
:Peter: I think the, the current Western
industrial idea is that more is better.
379
:That, I can and have, more than you.
380
:And if I have more than you,
then I am more valuable than you.
381
:I think the rise of dystopian fiction
is kind of an exploration of that.
382
:You know, I, because I think
dystopian fiction is all about
383
:the devaluation of the human.
384
:Ryan: Yeah.
385
:Peter: And tends to be about the
accumulation of power amongst the few.
386
:Ryan: Mm-hmm.
387
:Peter: And the division of haves and
have-nots and, you know, some few people
388
:at the top on the island are in the sky
or on the special planet or whatever.
389
:And the protagonists being
the undervalued, struggling
390
:people without resource.
391
:Um, and that with a real understanding of
both the nature of consciousness and the
392
:nature of reality, which will go together.
393
:Ryan: Mm-hmm.
394
:Peter: If we understand the nature
of consciousness, then we will
395
:understand the nature of reality.
396
:And once we have that understanding,
this idea of have and have
397
:not won't make any sense.
398
:And I think when that shift
happens, where it becomes
399
:viewed as scientifically proven.
400
:Ryan: Right?
401
:Peter: Right.
402
:It, it has the imprimatur of, oh,
the scientists have shown this.
403
:Then human culture will be able
to shift back to this harmonious,
404
:kind of back to the garden, really.
405
:Right?
406
:So going way back to Joseph
Campbell and the garden, we lost
407
:the garden because of an idea.
408
:Ryan: Yeah.
409
:Peter: Or knowledge.
410
:But I mean, basically
it's a way of thinking.
411
:Ryan: Yeah.
412
:Peter: That I think it's pretty
trivial to hypothesize that that's
413
:talking about materialist paradigm.
414
:Ryan: Mm-hmm.
415
:Peter: Once you start thinking
that I know I need clothes.
416
:Clothes are important.
417
:Everything to get clothes and,
you know, everything I do.
418
:And God's not important.
419
:Ryan: Mm-hmm.
420
:Peter: It's the fact that
I'm naked, that's important.
421
:That now you've lost, you've lost
security, you've lost happiness.
422
:And the consistent message from these
thinkers that we're trying to listen
423
:to and read is that there's a very real
possibility that, by pursuing science
424
:in the right way, we can actually bring
humanity from the brink of dystopia, to
425
:this golden age, return to to harmony.
426
:Which is a very compelling idea,
a very compelling idea being put
427
:forward by people who seem not to
be crackpots on the street corner.
428
:Ryan: Right.
429
:Peter: I mean, people are
seriously pursuing this.
430
:Ryan: Yeah.
431
:Using the scientific method.
432
:Peter: Mm-hmm.
433
:Ryan: Well, I found this speaker quite
interesting to listen to, and I was
434
:inspired that there is a place in the
institution of science to come to this
435
:intellectually and scientifically.
436
:Not just from people who have had
experiences, but that there's a growing
437
:understanding that the materialist
paradigm is limiting us, and it's
438
:time to start expanding our concept
and considering an alternate view
439
:of how this all comes together.
440
:I would definitely encourage
everybody to watch the interview.
441
:I found it interesting, even if
you're not super scientifically
442
:inclined, it was interesting.
443
:So we'll link that and
the Essentia Foundation.
444
:There's other links to nanobiosym.com,
445
:that is Dr.
446
:Goel's company, and also the link to her
plenary discussion, so you could see both
447
:the interview and her plenary presentation
at the symposium; and if you watch
448
:it, let us know what you think of it.
449
:Till next time, talk to you later.
450
:Peter: Great.
451
:Thanks.
452
:Bye.
453
:Thank you for listening to
the Tracking Wisdom podcast.
454
:Join us next time as we
continue the discussion.
455
:Don't forget to follow us on
Facebook, Instagram, and YouTube,
456
:and visit www.eth-studio.com
457
:for more information and content