Could one overlooked molecule be the key to fixing erectile dysfunction?
In this episode, we dig into the science behind nitric oxide, the body's natural "on switch" for blood flow and performance. You’ll learn why this molecule is so important and how it plays a critical role in erectile health. I'm breaking down myths, exposing real causes, and pointing you in the direction of solutions that work.
Tune in to uncover what might really be behind your erectile dysfunction, and how to take control of it.
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Resources mentioned:
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This podcast is for you, the Modern Man. I'm Dr Anne Truong,
Speaker:your host. I'm an intimate health medical doctor and best
Speaker:selling author of the book, Erectile Dysfunction Fix. I'll
Speaker:do a deep dive into sexual health and performance and how
Speaker:it affects men of all ages and backgrounds. So let's get
Speaker:started, and be sure to visit my website at
Speaker:sexualhealthformenpodcast.com for more information and
Speaker:resources from the show. See you on the inside.
Speaker:Hello there, Modern Man. Today we're tackling a topic that a
Speaker:lot of you have been curious about. Honestly, it's way more
Speaker:interesting than you think. We're talking about nitric oxide
Speaker:and why it's basically the biological "on switch" button
Speaker:for erection. Don't worry, this is science, not awkwardness. So
Speaker:stick around. So I'm Dr Anne Truong. I've treated over 7000
Speaker:men with ED. Before we talk about chemistry, let's
Speaker:understand a mechanic.
Speaker:An erection is essentially a hydraulic system. Think of it
Speaker:like a hydraulic press. You got two spongy cylinders running up
Speaker:and down the penis called the corpus cavernosa, which are
Speaker:these muscles right here running down both sides of the penis.
Speaker:When you're not aroused, so when you're not aroused, blood flows
Speaker:in and out normally, and everything stays relaxed. When
Speaker:arousal happens, something changes. The arteries feeding
Speaker:into the penis suddenly open up. They get much wider. Blood
Speaker:rushes and faster, at the same time, the veins that normally
Speaker:drain the blood out of the penis into the body, when blood fills
Speaker:in the vein, then get compressed. Then therefore the
Speaker:blood is trapped inside the corpus cavernosa. The pressure
Speaker:builds up inside the corpus cavanosa, the tissue become firm
Speaker:and enlarge and boom, you got an erection.
Speaker:But here's a key question, what tell these arteries to open up
Speaker:in the first place? So the answer is a tiny molecule called
Speaker:nitric oxide or NO. When you're sexually aroused, whether it's
Speaker:from physical touch, visual stimulus, or just thought, the
Speaker:nerves in the penis and the cells lining the blood vessel
Speaker:start to pump out nitric oxide. So nitric oxide is a gas. It's
Speaker:incredibly, very small, is basically just spread out and
Speaker:diffuses into the nearby muscle cells that surround the blood
Speaker:vessels and the corpus cavernosa. So once nitric oxide
Speaker:gets inside those smooth muscle cells or the corpus cavernosa,
Speaker:it triggers a chain reaction. Nitric oxide activate an enzyme
Speaker:called guanylate cyclase. Guanylate cyclase produces more
Speaker:of a molecule called CGMP or cyclic GMP. Which the cyclic GMP
Speaker:lower the amount of calcium inside the smooth muscle cell,
Speaker:so then lower calcium, smooth muscle relaxation. The cyclic
Speaker:GMP is what caused the lower calcium.
Speaker:Men, struggling to stay hard? Most of the time it comes down
Speaker:to poor blood flow. That's why I put together the Good Morning
Speaker:Wood smoothie, a nutrient packed blend designed to restore blood
Speaker:flow naturally. My patient often notice improvement in just a few
Speaker:weeks when they take this part of their daily routine. Click
Speaker:the link below to get the recipe and start boosting your blood
Speaker:flow and firmness today, or go to goodmorningwoodsmoothie.com.
Speaker:So here's the thing, when smooth muscle relaxes, arteries open
Speaker:up. When arteries open up, blood rushes in, and the rest is
Speaker:physics. So nitric oxide is basically the "on switch"
Speaker:button. Without it, the system never gets trigger. The artery
Speaker:stays narrow, the blood doesn't rush in and you don't get an
Speaker:erection. If it's not a physiological failure. That's
Speaker:just the biological default then. Okay?
Speaker:So now here's where it gets really real. Nitric oxide
Speaker:production isn't automatic and unchangeable. It can be damaged
Speaker:or reduced by a bunch of things, smoking damage the cells that
Speaker:produce nitric oxide. Diabetes interfere with nitric oxide
Speaker:signaling. High blood pressure reduces nitric oxide
Speaker:availability. High cholesterol clogs the arteries and impair
Speaker:nitric oxide function. Vascular disease or heart disease reduce
Speaker:the health of the blood vessel lining. Ageing reduces the
Speaker:production of nitric oxide, which is the enzyme. And chronic
Speaker:stress and a poor diet also decrease nitric oxide level. So
Speaker:a lot of common things that we do on an everyday basis. Now,
Speaker:what happened is that when nitric oxide production stop,
Speaker:the "on switch" button become faulty or weak, and that's when
Speaker:ED becomes more common. Study shows that men with ED often
Speaker:have lower level of nitric oxide or broken nitric oxide signaling
Speaker:pathway. But the thing is, it's not about willpower or mental
Speaker:toughness. It's really chemistry. Nitric oxide isn't
Speaker:working right, so the plumbing doesn't work right either. So
Speaker:the important thing is where, this is where pharmaceutical
Speaker:like Viagra and Cialis and Levitra come in. The drugs are
Speaker:called PDE-5 inhibitors. But here's the key. They don't
Speaker:create nitric oxide. They don't generate the "on switch".
Speaker:Instead, they preserve the nitric oxide so it will stay
Speaker:there longer. Now, remember how I say cyclic GMP is a molecule
Speaker:that tell the smooth muscle relax. Well, there's an enzyme
Speaker:called PDE-5 and that naturally break down the cyclic GMP over
Speaker:time. So the PDE-5 inhibitor, like Viagra, Cialis, block that
Speaker:enzyme. So that way nitric oxide last longer and cyclic GMP stays
Speaker:longer. So the smooth muscles, they relax longer. That's how
Speaker:blood stays trapped longer. But this is important. Pay attention
Speaker:to this. If there is very little nitric oxide in your body in the
Speaker:first place, these drugs won't help. You cannot amplify a weak
Speaker:signal indefinitely. So that's where these medication work
Speaker:better in men who still have reasonable nitric oxide
Speaker:production. But remember all those conditions that I
Speaker:mentioned earlier that decrease nitric oxide. Essentially, if
Speaker:you're 45 years old, you already lost half of the ability to make
Speaker:nitric oxide just from aging. So the older you're taking PDE-5
Speaker:inhibitors like Viagra, it may not work for you because you do
Speaker:not have nitric oxide production. So this is also why
Speaker:lifestyle changes like exercise, quitting smoking, managing
Speaker:stress and eating better can actually improve ED, because all
Speaker:those things boost nitric oxide production. So that's what I've
Speaker:been saying all these years. Focus on the root cause of your
Speaker:ED instead just bandaiding it with the medication.
Speaker:So before we wrap up, it's worth knowing that nitric oxide isn't
Speaker:just about erection. It's everywhere in the body. It
Speaker:regulate blood pressure, it reduces inflammation, it improve
Speaker:blood flow to your brain, and it support immune function.
Speaker:Athletes actually trained in ways that boost nitric oxide to
Speaker:improve performance. So when we talk about improving nitric
Speaker:oxide production through exercise, diet and avoiding
Speaker:smoking, we're not just fixing one problem. We're supporting
Speaker:your heart health, your mental clarity and even longevity. So
Speaker:ED is just one visible marker of overall vascular and metabolic
Speaker:health.
Speaker:Okay, modern man. If you're struggling with weak erection,
Speaker:low energy, the food you eat could be the big part of the
Speaker:problem. One of the best research pathways to boost
Speaker:circulation, support healthy testosterone and improve sexual
Speaker:performance is the Mediterranean diet. It's packed with food that
Speaker:open up your blood vessel, lower inflammation, and fuel your
Speaker:hormone, naturally. I've seen men notice real improvement in
Speaker:both energy and erection within weeks when they shift to this
Speaker:style of eating. So check out the Mediterranean diet link
Speaker:right here below, and get that as soon as you can. Stronger
Speaker:testosterone and better erection.
Speaker:Here's what you need to remember. Erections are
Speaker:hydraulic. Blood needs to rush in and gets trapped. Nitric
Speaker:oxide is a trigger. It tells the smooth muscle to relax, which
Speaker:open up blood vessel and allows blood to flow in. Number three,
Speaker:nitric oxide can fail. Meaning smoking, chronic stress, aging
Speaker:and poor lifestyle can really suppress nitric oxide
Speaker:production. Number four, medication amplify the signal.
Speaker:They don't create it. Viagra works better when nitric oxide
Speaker:is still functioning reasonably well. Number five, healthy
Speaker:lifestyle equal more nitric oxide equals better erection.
Speaker:Exercise, Mediterranean diet, stress management, quit smoking,
Speaker:all boost nitric oxide. And honestly, understanding the
Speaker:science remove a lot of shame and confusion. ED isn't a
Speaker:personal failure, guys. It's a sign that something is going on
Speaker:in your body, in your vascular system, your metabolic system,
Speaker:needs attention and tweaking, and it's actually fixable.
Speaker:So if you found this helpful, please like and subscribe to the
Speaker:channel. About 80% of the people watching our channel are
Speaker:non-subscribers. So do me a favor and push that subscribe
Speaker:button. And just know that ED is reversible as long as you treat
Speaker:the root cause of the problem. Okay? Because it's not just
Speaker:about erection. It's really about your health and living
Speaker:longer. Just know that you do not have to suffer in silence.
Speaker:There are alternatives to ED, Modern Man. And then I want you
Speaker:to know that we're here to help you. Check out the link below
Speaker:here on how I can help you get out of ED and all the resources
Speaker:that we have. Particularly check out our store at EDNoMore.com
Speaker:where we have all the supplements such as nitric oxide
Speaker:and the penis pump for you to start rehabbing and for you to
Speaker:start rehabbing your ED again. Just know you're not alone and
Speaker:you're not broken. See you in the next episode, Modern Man.
Speaker:Okay, Modern Man, you are not alone and you don't have to
Speaker:suffer anymore. ED can feel isolating, frustrating, and even
Speaker:defeating. The endless guessing, the quiet shame, the weight of
Speaker:not feeling like yourself is exhausting. But here's the
Speaker:truth, you are not broken. You are not alone. You don't have to
Speaker:figure this out alone anymore. The Get Wood Now Boost Program
Speaker:is your step by step, path to sexual confidence and
Speaker:restoration. No more suffering in silence, no more trial and
Speaker:error, just real solution, real result and the confidence you
Speaker:deserve. It's time to take back your power on your term. Let's
Speaker:get this journey started together. Check out the course
Speaker:at getwoodnow.com. I'll see you there.
Speaker:Thanks for listening to the Sexual Health for Men Podcast.
Speaker:If you love this episode, then please take a screenshot on your
Speaker:phone and post it on Facebook, Instagram, or wherever you post,
Speaker:and be sure to tag me and let me know why you like this episode
Speaker:and what you like to hear in the future. That will help me know
Speaker:what's great for you and I would love to give you the most
Speaker:incredible free gift designed to help you improve performance
Speaker:quickly. Go to my website at sexualhealthformenpodcast.com to
Speaker:get the book, The Five Common Costly Mistakes Men Make When
Speaker:Facing ED. I would appreciate if you subscribe, leave a review on
Speaker:Apple podcasts or wherever you listen. And just know that you
Speaker:can have sexual vitality for life. I appreciate you until
Speaker:next time.