Episode 79 - Transcript

[00:00:24] Things that you can do to support yourself and your families and your patients to achieve optimal wellness. I'm Dr. Ritamarie Loscalzo, and we're going to talk about detoxification, and you probably hear a lot of things talking about detoxification, but today we're going to tie together detoxification.

[00:01:08] We don't call them genetic defects anymore. We call them variants, and it's very important to note, because you know what the difference between blue eyes and brown eyes is a genetic SNP, and those of us with brown eyes would really not like it if you said We had a mutation that caused us to have brown eyes.

[00:01:48] So many new companies coming out with new and wonderful genetic testing. And I want you to understand it. It's going to take a long time to become an expert in this. And in my opinion, nobody's an expert in it right now 'cause it's a new science. Okay. I've studied it a lot, but I am by no means an expert. So today I want to talk about some of the genetic detoxification SNPs, the SNPs in the pathways that help us with detoxification and face it.

[00:02:41] Then we'll talk about ways that you can actually test someone to see if there are some variants out there that are actually causing their genetic pathways to be sluggish. Then we'll talk about what do you do to support mainly the liver, but other organs do detoxification. We have phase one and phase two, so in terms of detoxification, SNPs, we have a whole bunch of them in the CYP category, Cytochrome P450, and those are phase one detoxification SNPs, and they have a role in detoxifying a lot of the environmental toxins.

[00:03:44] Say, well, why does caffeine have to be detoxified? Well, 'cause caffeine is toxic to the body and the liver has to put it through some phases to make it less toxic to the body. Caffeine, you know, we find it in coffee, the most common, like 85% of the population drinks coffee and is addicted to it. By the way, coffee Tea, black tea especially, but also a little bit in green tea, and then chocolate, a little bit in chocolate.

[00:04:31] So when we have SNPs in these areas, for example, the [CYP]1B1, That's involved with aflatoxin. Aflatoxin is a common toxin produced by molds on things like peanuts and also grains when they sit in those grain silos. So those are important ones, and there's also a lot of other toxins that go through these pathways that we find in our foods, in our pesticides, et cetera.

[00:05:15] So there's CYP 2C9. There's also CYP1D4, bunch of others, and they're all involved with the drug metabolism, the monoamine oxidase, the dopamine, serotonin, all those pathways. We also have glutathione. Glutathione is the grandmother mama of the detoxification enzymes of the substances.

[00:05:59] So these are really important. MTHFR, MTRR, MTR, MMAB, MUT. All of these are important and when there's disruptions in these, We're going to have disruptions in the detoxification of those things. So the other thing that I look at all the time is there's a gene, a GeneSNP called for detoxification initiation.

[00:06:51] So these are really important. There's also another one, PON-1 which has to do with pesticides and herbicides and especially can have problems with the heart when that enzyme isn't working properly. Then we have two other master antioxidants, SOD and catalase, and so when you have someone who has disruptions, potential disruptions in these pathways because their genes are showing snips, then you want to be really careful and watch and do some fancy testing so that you know, are these really activated?

[00:07:43] So you can have the genes, but then the activation is gotta be looked at. So that's a great test to look at. So then on the blood test, there's the whole liver section, right? So you have AST, ALT, alkaline phosphatase, and one of the most important ones, That people leave out these days. A lot of doctors are just leaving out GGT. GGT has been known for being able to tell for detoxification or toxicity from alcohol, but also the level of toxins in the body. And then we have things that are methylation markers, like elevated homocysteine, elevated MCV, mean corpuscular volume. So if you test these things and you find a bunch of these detoxification snips, May be active based on the lab testing, then you've gotta do something about it.

[00:08:57] Then you guide people. You educate people as to how to avoid the various substances that are detoxed by the pathways that seem to be not activated well. So cleanup, environmental cleanup, which you should be doing with everybody anyway, but cleaning up the household products. Getting rid of the toxic household products, so we're not breathing in all this kind of toxic fumes that the liver can't even handle.

[00:09:48] One of the things that you also want to teach them to do is avoid food additives and toxins in the food supply. So, alcohol, caffeine, sugar, they all have a load on the body and we want to. Detox, we want to lighten the toxic load. I call it everyday detox. And I have a whole module in our programs for clients that teaches them about what does everyday detox look like.

[00:10:35] I personally also recommend people avoid common allergens just because it creates an inflammatory process in the body. So like gluten, dairy, corn, soy, eggs, peanuts, those are really important to avoid, to minimize. The burden on the body. We want to avoid processed meats with the nitrites and all sorts of stuff, the bologna and the salami and all that.

[00:11:19] There's artificial colors and flavors in so many things. If we can avoid those, it's going to lighten the toxic burden. It's going to lighten the load. Some people are going to be sensitive to nightshades. If so, you avoid those. So any kinds of food, salicylates, nightshades, oxalates, that they may be sensitive to, identify those and eliminate those.

[00:12:05] Frankfurters hot dogs, those are the worst things, right? So we help people to get off of all of that kind of stuff, and we talk to them about how important it is, especially for women with breasts and uterus and other estrogen sensitive tissue in the body, but also men because. Men can get breast cancer too.

[00:12:47] And when we can't methylate, it leads to a whole host of problems, and you can look that up and study that. It's everything from exhaustion and fatigue and anemia, all the way to miscarriages and still births and things like that. So we really want to make sure that these methylation pathways aren't overly taxed.

[00:13:28] Jet fuel for people who are pilots or in the industry, they're going to be exposed to that a lot. Benzene, we see that a lot in chemicals. People who work in plants mold, toxins like aflotoxin. And these are things that we can avoid and we have to make choices. Teach people to make choices, to avoid heavy metals like arsenic and mercury and cadmium and lead.

[00:14:23] And so you list all the products that may contain toxic ingredients. You have them actually read everything and what are some alternatives, right? There's so many good books. Back in the day, 35 years ago, when I first started getting into Health, there was a book by Deborah and Dad?, which showed you exactly how to make these products and replace your products with things that you ordinarily have at home.

[00:15:04] So they just throw everything away. Others are like, well, I got a half a bottle left of this and I have three quarters of a bottle left of this fine. You help them to put together a phase out plan. I. So I'll just throw in a few other things that you can help people to add to their diets, and I highly recommend that you look some of these up and study them.

[00:15:45] Burdock root, burdock buying most grocery stores, at least most of the gourmet type stores, but they look like a long, skinny potatoes. They look kind of like the shape of a carrot, but they're dark on the outside and you have to scrape 'em real well. But they are so, so supportive of liver. Dandelion, you can do the leaves or the root.

[00:16:28] Great. That's Hawthorne Berries. And you can actually buy dried Hawthorne berries from someplace like Mountain rose herbs and other herbs suppliers. And when you buy them, you just soak them. I usually will boil some water, pour it over them, let them sit and steep for 15 minutes or so. Now they're nice and soft.

[00:17:10] And there's so much talk about genetics these days, and there's so many companies that are saying, just run my genetic report and I'll give you a custom supplement program. That's not how it works, right? We have to look to see which of those steps might be impacting them. What are the habits that are going to stress those pathways that they have those genetic SNPs for?

[00:17:49] And I don't know about you, but that's what I'm here for. So go ahead and check out our page ine method.com and learn more about how we can support you with this visit. The other episodes in the podcast, we have a ton of them on genetics and Cleansing and all this, so please enjoy all the resources we're putting out there, and until next time, shine on.